582 related articles for article (PubMed ID: 12084458)
1. Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase.
Banerjee D; Mayer-Kuckuk P; Capiaux G; Budak-Alpdogan T; Gorlick R; Bertino JR
Biochim Biophys Acta; 2002 Jul; 1587(2-3):164-73. PubMed ID: 12084458
[TBL] [Abstract][Full Text] [Related]
2. mRNA expression levels of E2F transcription factors correlate with dihydrofolate reductase, reduced folate carrier, and thymidylate synthase mRNA expression in osteosarcoma.
Sowers R; Toguchida J; Qin J; Meyers PA; Healey JH; Huvos A; Banerjee D; Bertino JR; Gorlick R
Mol Cancer Ther; 2003 Jun; 2(6):535-41. PubMed ID: 12813132
[TBL] [Abstract][Full Text] [Related]
3. Retroviral transduction of a mutant dihydrofolate reductase-thymidylate synthase fusion gene into murine marrow cells confers resistance to both methotrexate and 5-fluorouracil.
Capiaux GM; Budak-Alpdogan T; Takebe N; Mayer-Kuckuk P; Banerjee D; Maley F; Bertino JR
Hum Gene Ther; 2003 Mar; 14(5):435-46. PubMed ID: 12691609
[TBL] [Abstract][Full Text] [Related]
4. Molecular mechanisms of resistance to antifolates, a review.
Banerjee D; Ercikan-Abali E; Waltham M; Schnieders B; Hochhauser D; Li WW; Fan J; Gorlick R; Goker E; Bertino JR
Acta Biochim Pol; 1995; 42(4):457-64. PubMed ID: 8852336
[TBL] [Abstract][Full Text] [Related]
5. Combined gene deletion of dihydrofolate reductase-thymidylate synthase and pteridine reductase in Leishmania infantum.
Bhattacharya A; Leprohon P; Ouellette M
PLoS Negl Trop Dis; 2021 Apr; 15(4):e0009377. PubMed ID: 33905412
[TBL] [Abstract][Full Text] [Related]
6. Expression of thymidylate synthase, thymidine phosphorylase, dihydropyrimidine dehydrogenase, E2F-1, Bak, Bcl-X, and Bcl-2, and clinical outcomes for gastric cancer patients treated with bolus 5-fluorouracil.
Tahara M; Ochiai A; Fujimoto J; Boku N; Yasui W; Ohtsu A; Tahara E; Yoshida S
Oncol Rep; 2004 Jan; 11(1):9-15. PubMed ID: 14654896
[TBL] [Abstract][Full Text] [Related]
7. Human dihydrofolate reductase and thymidylate synthase form a complex in vitro and co-localize in normal and cancer cells.
Antosiewicz A; Jarmuła A; Przybylska D; Mosieniak G; Szczepanowska J; Kowalkowska A; Rode W; Cieśla J
J Biomol Struct Dyn; 2017 May; 35(7):1474-1490. PubMed ID: 27187663
[TBL] [Abstract][Full Text] [Related]
8. Protection of hematopoietic stem cells from pemetrexed toxicity by retroviral gene transfer with a mutant dihydrofolate reductase-mutant thymidylate synthase fusion gene.
Capiaux GM; Budak-Alpdogan T; Alpdogan O; Bornmann W; Takebe N; Banerjee D; Maley F; Bertino JR
Cancer Gene Ther; 2004 Dec; 11(12):767-73. PubMed ID: 15359285
[TBL] [Abstract][Full Text] [Related]
9. Role of the locus and of the resistance gene on gene amplification frequency in methotrexate resistant Leishmania tarentolae.
Kündig C; Leblanc E; Papadopoulou B; Ouellette M
Nucleic Acids Res; 1999 Sep; 27(18):3653-9. PubMed ID: 10471733
[TBL] [Abstract][Full Text] [Related]
10. Real-time RT-PCR (TaqMan) of tumor mRNA to predict sensitivity of specimens to 5-fluorouracil.
Kubota T
Methods Mol Med; 2005; 111():257-65. PubMed ID: 15911984
[TBL] [Abstract][Full Text] [Related]
11. Drug-resistant dihydrofolate reductases: generation, expression and therapeutic application.
McIvor RS
Bone Marrow Transplant; 1996 Dec; 18 Suppl 3():S50-4. PubMed ID: 8971409
[TBL] [Abstract][Full Text] [Related]
12. Predictive role of thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase expression in colorectal cancer patients receiving adjuvant 5-fluorouracil.
Ciaparrone M; Quirino M; Schinzari G; Zannoni G; Corsi DC; Vecchio FM; Cassano A; La Torre G; Barone C
Oncology; 2006; 70(5):366-77. PubMed ID: 17179731
[TBL] [Abstract][Full Text] [Related]
13. Dihydropyrimidine dehydrogenase but not thymidylate synthase expression is associated with resistance to 5-fluorouracil in colorectal cancer.
Nita ME; Tominaga O; Nagawa H; Tsuruo T; Muto T
Hepatogastroenterology; 1998; 45(24):2117-22. PubMed ID: 9951876
[TBL] [Abstract][Full Text] [Related]
14. Translational up-regulation of antifolate drug targets in the human malaria parasite Plasmodium falciparum upon challenge with inhibitors.
Nirmalan N; Sims PF; Hyde JE
Mol Biochem Parasitol; 2004 Jul; 136(1):63-70. PubMed ID: 15138068
[TBL] [Abstract][Full Text] [Related]
15. Recent advances in the study of rTS proteins. rTS expression during growth and in response to thymidylate synthase inhibitors in human tumor cells.
Dolnick BJ; Lu K; Yin MB; Rustum YM
Adv Enzyme Regul; 1997; 37():95-109. PubMed ID: 9381988
[TBL] [Abstract][Full Text] [Related]
16. The role of thymidylate synthase and dihydropyrimidine dehydrogenase in resistance to 5-fluorouracil in human lung cancer cells.
Oguri T; Achiwa H; Bessho Y; Muramatsu H; Maeda H; Niimi T; Sato S; Ueda R
Lung Cancer; 2005 Sep; 49(3):345-51. PubMed ID: 15993511
[TBL] [Abstract][Full Text] [Related]
17. Correlation of thymidylate synthase, thymidine phosphorylase and dihydropyrimidine dehydrogenase with sensitivity of gastrointestinal cancer cells to 5-fluorouracil and 5-fluoro-2'-deoxyuridine.
Ma T; Zhu ZG; Ji YB; Zhang Y; Yu YY; Liu BY; Yin HR; Lin YZ
World J Gastroenterol; 2004 Jan; 10(2):172-6. PubMed ID: 14716816
[TBL] [Abstract][Full Text] [Related]
18. Thymidylate synthase as a target for growth inhibition in methotrexate-sensitive and -resistant human head and neck cancer and leukemia cell lines.
McGuire JJ; Magee KJ; Russell CA; Canestrari JM
Oncol Res; 1997; 9(3):139-47. PubMed ID: 9220499
[TBL] [Abstract][Full Text] [Related]
19. Intratumoural thymidylate synthase and dihydropyrimidine dehydrogenase activities are good predictors of 5-fluorouracil sensitivity in colorectal cancer.
Ishibiki Y; Kitajima M; Sakamoto K; Tomiki Y; Sakamoto S; Kamano T
J Int Med Res; 2003; 31(3):181-7. PubMed ID: 12870370
[TBL] [Abstract][Full Text] [Related]
20. Cancer research: from folate antagonism to molecular targets.
Bertino JR
Best Pract Res Clin Haematol; 2009 Dec; 22(4):577-82. PubMed ID: 19959110
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
