503 related articles for article (PubMed ID: 12084461)
1. Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism.
Peters GJ; Backus HH; Freemantle S; van Triest B; Codacci-Pisanelli G; van der Wilt CL; Smid K; Lunec J; Calvert AH; Marsh S; McLeod HL; Bloemena E; Meijer S; Jansen G; van Groeningen CJ; Pinedo HM
Biochim Biophys Acta; 2002 Jul; 1587(2-3):194-205. PubMed ID: 12084461
[TBL] [Abstract][Full Text] [Related]
2. Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines.
van Triest B; Pinedo HM; van Hensbergen Y; Smid K; Telleman F; Schoenmakers PS; van der Wilt CL; van Laar JA; Noordhuis P; Jansen G; Peters GJ
Clin Cancer Res; 1999 Mar; 5(3):643-54. PubMed ID: 10100718
[TBL] [Abstract][Full Text] [Related]
3. Modulation of both endogenous folates and thymidine enhance the therapeutic efficacy of thymidylate synthase inhibitors.
van der Wilt CL; Backus HH; Smid K; Comijn L; Veerman G; Wouters D; Voorn DA; Priest DG; Bunni MA; Mitchell F; Jackman AL; Jansen G; Peters GJ
Cancer Res; 2001 May; 61(9):3675-81. PubMed ID: 11325838
[TBL] [Abstract][Full Text] [Related]
4. Novel chemical strategies for thymidylate synthase inhibition.
Gmeiner WH
Curr Med Chem; 2005; 12(2):191-202. PubMed ID: 15638735
[TBL] [Abstract][Full Text] [Related]
5. Comparative cytotoxicity of folate-based inhibitors of thymidylate synthase and 5-fluorouracil +/- leucovorin in MGH-U1 cells.
Erlichman C; Mitrovski B
Cancer Chemother Pharmacol; 1994; 34(1):51-6. PubMed ID: 8174202
[TBL] [Abstract][Full Text] [Related]
6. Folate depletion increases sensitivity of solid tumor cell lines to 5-fluorouracil and antifolates.
Backus HH; Pinedo HM; Wouters D; Padrón JM; Molders N; van Der Wilt CL; van Groeningen CJ; Jansen G; Peters GJ
Int J Cancer; 2000 Sep; 87(6):771-8. PubMed ID: 10956384
[TBL] [Abstract][Full Text] [Related]
7. Thymidylate synthase and drug resistance.
Peters GJ; van der Wilt CL; van Triest B; Codacci-Pisanelli G; Johnston PG; van Groeningen CJ; Pinedo HM
Eur J Cancer; 1995; 31A(7-8):1299-305. PubMed ID: 7577040
[TBL] [Abstract][Full Text] [Related]
8. The role of thymidylate synthase induction in modulating p53-regulated gene expression in response to 5-fluorouracil and antifolates.
Longley DB; Boyer J; Allen WL; Latif T; Ferguson PR; Maxwell PJ; McDermott U; Lynch M; Harkin DP; Johnston PG
Cancer Res; 2002 May; 62(9):2644-9. PubMed ID: 11980662
[TBL] [Abstract][Full Text] [Related]
9. Mechanisms of action of FdUMP[10]: metabolite activation and thymidylate synthase inhibition.
Bijnsdorp IV; Comijn EM; Padron JM; Gmeiner WH; Peters GJ
Oncol Rep; 2007 Jul; 18(1):287-91. PubMed ID: 17549381
[TBL] [Abstract][Full Text] [Related]
10. Downstream molecular determinants of response to 5-fluorouracil and antifolate thymidylate synthase inhibitors.
Van Triest B; Pinedo HM; Giaccone G; Peters GJ
Ann Oncol; 2000 Apr; 11(4):385-91. PubMed ID: 10847455
[TBL] [Abstract][Full Text] [Related]
11. High-dose 5-Fluorouracil with uridine-diphosphoglucose rescue increases thymidylate synthase inhibition but not 5-Fluorouracil incorporation into RNA in murine tumors.
Codacci-Pisanelli G; Van der Wilt CL; Smid K; Noordhuis P; Voorn D; Pinedo HM; Peters GJ
Oncology; 2002; 62(4):363-70. PubMed ID: 12138245
[TBL] [Abstract][Full Text] [Related]
12. Cross-resistance to antifolates in multidrug resistant cell lines with P-glycoprotein or multidrug resistance protein expression.
van Triest B; Pinedo HM; Telleman F; van der Wilt CL; Jansen G; Peters GJ
Biochem Pharmacol; 1997 Jun; 53(12):1855-66. PubMed ID: 9256160
[TBL] [Abstract][Full Text] [Related]
13. Effects of antifolates on the binding of 5-fluoro-2'-deoxyuridine monophosphate to thymidylate synthase.
van der Wilt CL; Smid K; Peters GJ
Biochem Pharmacol; 2002 Aug; 64(4):669-75. PubMed ID: 12167486
[TBL] [Abstract][Full Text] [Related]
14. Combination studies of antifolates with 5-fluorouracil in colon cancer cell lines.
van der Wilt CL; Kuiper CM; Peters GJ
Oncol Res; 1999; 11(8):383-91. PubMed ID: 10803742
[TBL] [Abstract][Full Text] [Related]
15. UCN-01 (7-hydroxystaurosporine) enhances 5-fluorouracil cytotoxicity through down-regulation of thymidylate synthetase messenger RNA.
Abe S; Kubota T; Otani Y; Furukawa T; Watanabe M; Kumai K; Kitajima M
Jpn J Cancer Res; 2000 Nov; 91(11):1192-8. PubMed ID: 11092986
[TBL] [Abstract][Full Text] [Related]
16. Induction of resistance to the multitargeted antifolate Pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpression.
Sigmond J; Backus HH; Wouters D; Temmink OH; Jansen G; Peters GJ
Biochem Pharmacol; 2003 Aug; 66(3):431-8. PubMed ID: 12907242
[TBL] [Abstract][Full Text] [Related]
17. Differences in the induction of DNA damage, cell cycle arrest, and cell death by 5-fluorouracil and antifolates.
Backus HH; Pinedo HM; Wouters D; Kuiper CM; Jansen G; van Groeningen CJ; Peters GJ
Oncol Res; 2000; 12(5):231-9. PubMed ID: 11417748
[TBL] [Abstract][Full Text] [Related]
18. Nuclear thymidylate synthase expression, p53 expression and 5FU response in colorectal carcinoma.
Wong NA; Brett L; Stewart M; Leitch A; Longley DB; Dunlop MG; Johnston PG; Lessells AM; Jodrell DI
Br J Cancer; 2001 Dec; 85(12):1937-43. PubMed ID: 11747337
[TBL] [Abstract][Full Text] [Related]
19. Mechanism of acquired 5FU resistance and strategy for overcoming 5FU resistance focusing on 5FU metabolism in colon cancer cell lines.
Suetsugu T; Mori R; Futamura M; Fukada M; Tanaka H; Yasufuku I; Sato Y; Iwata Y; Imai T; Imai H; Tanaka Y; Okumura N; Matsuhashi N; Takahashi T; Yoshida K
Oncol Rep; 2021 Apr; 45(4):. PubMed ID: 33649846
[TBL] [Abstract][Full Text] [Related]
20. Effect of folinic acid on fluorouracil activity and expression of thymidylate synthase.
van der Wilt CL; Pinedo HM; Smid K; Cloos J; Noordhuis P; Peters GJ
Semin Oncol; 1992 Apr; 19(2 Suppl 3):16-25. PubMed ID: 1532671
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
