These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

252 related articles for article (PubMed ID: 12084819)

  • 1. Live-cell imaging reveals divergent intracellular dynamics of polyglutamine disease proteins and supports a sequestration model of pathogenesis.
    Chai Y; Shao J; Miller VM; Williams A; Paulson HL
    Proc Natl Acad Sci U S A; 2002 Jul; 99(14):9310-5. PubMed ID: 12084819
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CREB-binding protein sequestration by expanded polyglutamine.
    McCampbell A; Taylor JP; Taye AA; Robitschek J; Li M; Walcott J; Merry D; Chai Y; Paulson H; Sobue G; Fischbeck KH
    Hum Mol Genet; 2000 Sep; 9(14):2197-202. PubMed ID: 10958659
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Amino acid sequences flanking polyglutamine stretches influence their potential for aggregate formation.
    Nozaki K; Onodera O; Takano H; Tsuji S
    Neuroreport; 2001 Oct; 12(15):3357-64. PubMed ID: 11711886
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Intranuclear ataxin1 inclusions contain both fast- and slow-exchanging components.
    Stenoien DL; Mielke M; Mancini MA
    Nat Cell Biol; 2002 Oct; 4(10):806-10. PubMed ID: 12360291
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Quantification of Ataxin-3 and Ataxin-7 aggregates formed in vivo in Drosophila reveals a threshold of aggregated polyglutamine proteins associated with cellular toxicity.
    Vinatier G; Corsi JM; Mignotte B; Gaumer S
    Biochem Biophys Res Commun; 2015 Sep; 464(4):1060-1065. PubMed ID: 26210447
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Conformational targeting of fibrillar polyglutamine proteins in live cells escalates aggregation and cytotoxicity.
    Kvam E; Nannenga BL; Wang MS; Jia Z; Sierks MR; Messer A
    PLoS One; 2009 May; 4(5):e5727. PubMed ID: 19492089
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation.
    Perez MK; Paulson HL; Pendse SJ; Saionz SJ; Bonini NM; Pittman RN
    J Cell Biol; 1998 Dec; 143(6):1457-70. PubMed ID: 9852144
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential effects of polyglutamine proteins on nuclear organization and artificial reporter splicing.
    Sun J; Xu H; Negi S; Subramony SH; Hebert MD
    J Neurosci Res; 2007 Aug; 85(11):2306-17. PubMed ID: 17526020
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The role of protein composition in specifying nuclear inclusion formation in polyglutamine disease.
    Chai Y; Wu L; Griffin JD; Paulson HL
    J Biol Chem; 2001 Nov; 276(48):44889-97. PubMed ID: 11572863
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Caspase-mediated proteolysis of the polyglutamine disease protein ataxin-3.
    Berke SJ; Schmied FA; Brunt ER; Ellerby LM; Paulson HL
    J Neurochem; 2004 May; 89(4):908-18. PubMed ID: 15140190
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inefficient degradation of truncated polyglutamine proteins by the proteasome.
    Holmberg CI; Staniszewski KE; Mensah KN; Matouschek A; Morimoto RI
    EMBO J; 2004 Oct; 23(21):4307-18. PubMed ID: 15470501
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Aggregate formation inhibits proteasomal degradation of polyglutamine proteins.
    Verhoef LG; Lindsten K; Masucci MG; Dantuma NP
    Hum Mol Genet; 2002 Oct; 11(22):2689-700. PubMed ID: 12374759
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expanded polyglutamine domain proteins bind neurofilament and alter the neurofilament network.
    Nagai Y; Onodera O; Chun J; Strittmatter WJ; Burke JR
    Exp Neurol; 1999 Feb; 155(2):195-203. PubMed ID: 10072295
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Modulating huntingtin half-life alters polyglutamine-dependent aggregate formation and cell toxicity.
    Kaytor MD; Wilkinson KD; Warren ST
    J Neurochem; 2004 May; 89(4):962-73. PubMed ID: 15140195
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Soluble polyglutamine oligomers formed prior to inclusion body formation are cytotoxic.
    Takahashi T; Kikuchi S; Katada S; Nagai Y; Nishizawa M; Onodera O
    Hum Mol Genet; 2008 Feb; 17(3):345-56. PubMed ID: 17947294
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Formic acid dissolves aggregates of an N-terminal huntingtin fragment containing an expanded polyglutamine tract: applying to quantification of protein components of the aggregates.
    Hazeki N; Tukamoto T; Goto J; Kanazawa I
    Biochem Biophys Res Commun; 2000 Oct; 277(2):386-93. PubMed ID: 11032734
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Co-chaperone CHIP promotes aggregation of ataxin-1.
    Choi JY; Ryu JH; Kim HS; Park SG; Bae KH; Kang S; Myung PK; Cho S; Park BC; Lee DH
    Mol Cell Neurosci; 2007 Jan; 34(1):69-79. PubMed ID: 17127076
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An expanded glutamine repeat destabilizes native ataxin-3 structure and mediates formation of parallel beta -fibrils.
    Bevivino AE; Loll PJ
    Proc Natl Acad Sci U S A; 2001 Oct; 98(21):11955-60. PubMed ID: 11572942
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Research on screening and identification of proteins interacting with ataxin-3.
    Shen L; Tang JG; Tang BS; Jiang H; Zhao GH; Xia K; Zhang YH; Cai F; Tan LM; Pan Q
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi; 2005 Jun; 22(3):242-7. PubMed ID: 15952105
    [TBL] [Abstract][Full Text] [Related]  

  • 20. General transcriptional repression by polyglutamine disease proteins is not directly linked to the presence of inclusion bodies.
    Hoshino M; Tagawa K; Okuda T; Okazawa H
    Biochem Biophys Res Commun; 2004 Jan; 313(1):110-6. PubMed ID: 14672705
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.