116 related articles for article (PubMed ID: 12086486)
21. Synthesis and biological activity of N-(aminoiminomethyl)-1H-indole carboxamide derivatives as Na+/H+ exchanger inhibitors.
Kitano M; Kojima A; Nakano K; Miyagishi A; Noguchi T; Ohashi N
Chem Pharm Bull (Tokyo); 1999 Nov; 47(11):1538-48. PubMed ID: 10605052
[TBL] [Abstract][Full Text] [Related]
22. Quantitative structure-activity relationship study of N-(3-oxo-3,4-dihydro-2H-benzo[1,4]thiazine-6-carbonyl)guanidines as potent Na/H exchange inhibitors.
Yamamoto T; Hori M; Watanabe I; Harada K; Ikeda S; Ohtaka H
Chem Pharm Bull (Tokyo); 2000 Jun; 48(6):843-9. PubMed ID: 10866146
[TBL] [Abstract][Full Text] [Related]
23. Bicyclic acylguanidine Na+/H+ antiporter inhibitors.
Baumgarth M; Beier N; Gericke R
J Med Chem; 1998 Sep; 41(19):3736-47. PubMed ID: 9733499
[TBL] [Abstract][Full Text] [Related]
24. Inhibition of the Na(+)/H(+) exchanger confers greater cardioprotection against 90 minutes of myocardial ischemia than ischemic preconditioning in dogs.
Gumina RJ; Buerger E; Eickmeier C; Moore J; Daemmgen J; Gross GJ
Circulation; 1999 Dec 21-28; 100(25):2519-26; discussion 2469-72. PubMed ID: 10604890
[TBL] [Abstract][Full Text] [Related]
25. Cardioprotective effects of [5-(2-methyl-5-fluorophenyl)furan-2-ylcarbonyl]guanidine (KR-32568) in an anesthetized rat model of ischemia and reperfusion heart injury.
Roh HY; Jung IS; Park JW; Yun YP; Yi KY; Yoo SE; Kwon SH; Chung HJ; Shin HS
Pharmacology; 2005 Dec; 75(1):37-44. PubMed ID: 15942274
[TBL] [Abstract][Full Text] [Related]
26. Zoniporide: a potent and highly selective inhibitor of human Na(+)/H(+) exchanger-1.
Marala RB; Brown JA; Kong JX; Tracey WR; Knight DR; Wester RT; Sun D; Kennedy SP; Hamanaka ES; Ruggeri RB; Hill RJ
Eur J Pharmacol; 2002 Sep; 451(1):37-41. PubMed ID: 12223226
[TBL] [Abstract][Full Text] [Related]
27. Ligustrazine derivatives. Part 6: design, synthesis and evaluation of novel ligustrazinyl acylguanidine derivatives as potential cardiovascular agents.
Li Z; Yu F; Cui L; Zhan P; Wang S; Shen Y; Liu X
Med Chem; 2012 Sep; 8(5):928-33. PubMed ID: 22741791
[TBL] [Abstract][Full Text] [Related]
28. Rational basis for use of sodium-hydrogen exchange inhibitors in myocardial ischemia.
Avkiran M
Am J Cardiol; 1999 May; 83(10A):10G-17G; discussion 17G-18G. PubMed ID: 10482175
[TBL] [Abstract][Full Text] [Related]
29. Inhibition of the Na(+)/H(+) exchanger attenuates phase 1b ischemic arrhythmias and reperfusion-induced ventricular fibrillation.
Gumina RJ; Daemmgen J; Gross GJ
Eur J Pharmacol; 2000 May; 396(2-3):119-24. PubMed ID: 10822064
[TBL] [Abstract][Full Text] [Related]
30. Inhibition of Na+/H+ exchanger reduces infarct volume of focal cerebral ischemia in rats.
Kitayama J; Kitazono T; Yao H; Ooboshi H; Takaba H; Ago T; Fujishima M; Ibayashi S
Brain Res; 2001 Dec; 922(2):223-8. PubMed ID: 11743953
[TBL] [Abstract][Full Text] [Related]
31. Synthesis and Na+/H+ exchanger inhibitory activity of benzoylguanidine derivatives.
Jin L; Jiang XM; Du P; Xu J; Gong GQ; Wang QJ; Xu YG
Eur J Med Chem; 2011 Sep; 46(9):4107-16. PubMed ID: 21724305
[TBL] [Abstract][Full Text] [Related]
32. Role of nitric oxide and free radicals in cardioprotection by blocking Na+/H+ and Na+/Ca2+ exchange in rat heart.
Maczewski M; Beresewicz A
Eur J Pharmacol; 2003 Feb; 461(2-3):139-47. PubMed ID: 12586209
[TBL] [Abstract][Full Text] [Related]
33. Characterization of sabiporide, a new specific NHE-1 inhibitor exhibiting slow dissociation kinetics and cardioprotective effects.
Touret N; Tanneur V; Godart H; Seidler R; Taki N; Bürger E; Dämmgen J; Counillon L
Eur J Pharmacol; 2003 Jan; 459(2-3):151-8. PubMed ID: 12524140
[TBL] [Abstract][Full Text] [Related]
34. Identification of a potent sodium hydrogen exchanger isoform 1 (NHE1) inhibitor with a suitable profile for chronic dosing and demonstrated cardioprotective effects in a preclinical model of myocardial infarction in the rat.
Huber JD; Bentzien J; Boyer SJ; Burke J; De Lombaert S; Eickmeier C; Guo X; Haist JV; Hickey ER; Kaplita P; Karmazyn M; Kemper R; Kennedy CA; Kirrane T; Madwed JB; Mainolfi E; Nagaraja N; Soleymanzadeh F; Swinamer A; Eldrup AB
J Med Chem; 2012 Aug; 55(16):7114-40. PubMed ID: 22803959
[TBL] [Abstract][Full Text] [Related]
35. The myocardial Na+/H+ exchanger: a potential therapeutic target for the prevention of myocardial ischaemic and reperfusion injury and attenuation of postinfarction heart failure.
Karmazyn M; Sostaric JV; Gan XT
Drugs; 2001; 61(3):375-89. PubMed ID: 11293648
[TBL] [Abstract][Full Text] [Related]
36. Benzimidazol-2-yl or benzimidazol-2-ylthiomethyl benzoylguanidines as novel Na+/H+ exchanger inhibitors, synthesis and protection against ischemic-reperfusion injury.
Zhang R; Lei L; Xu YG; Hua WY; Gong GQ
Bioorg Med Chem Lett; 2007 May; 17(9):2430-3. PubMed ID: 17346962
[TBL] [Abstract][Full Text] [Related]
37. Pharmacological profile of SL 59.1227, a novel inhibitor of the sodium/hydrogen exchanger.
Lorrain J; Briand V; Favennec E; Duval N; Grosset A; Janiak P; Hoornaert C; Cremer G; Latham C; O'Connor SE
Br J Pharmacol; 2000 Nov; 131(6):1188-94. PubMed ID: 11082127
[TBL] [Abstract][Full Text] [Related]
38. Na(+)/H(+) exchange inhibitor cariporide attenuates cell injury predominantly during ischemia and not at onset of reperfusion in porcine hearts with low residual blood flow.
Klein HH; Pich S; Bohle RM; Lindert-Heimberg S; Nebendahl K
Circulation; 2000 Oct; 102(16):1977-82. PubMed ID: 11034948
[TBL] [Abstract][Full Text] [Related]
39. Hydrogen sulfide regulates Na+/H+ exchanger activity via stimulation of phosphoinositide 3-kinase/Akt and protein kinase G pathways.
Hu LF; Li Y; Neo KL; Yong QC; Lee SW; Tan BK; Bian JS
J Pharmacol Exp Ther; 2011 Nov; 339(2):726-35. PubMed ID: 21865440
[TBL] [Abstract][Full Text] [Related]
40. Myocardial protection by Na(+)-H+ exchange inhibition in ischemic, reperfused porcine hearts.
Klein HH; Pich S; Bohle RM; Wollenweber J; Nebendahl K
Circulation; 1995 Aug; 92(4):912-7. PubMed ID: 7641374
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]