These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

104 related articles for article (PubMed ID: 12086842)

  • 1. (Re-)Engineering tumor cell-selective replicating adenoviruses: a step in the right direction toward systemic therapy for metastatic disease.
    Dubensky TW
    Cancer Cell; 2002 May; 1(4):307-9. PubMed ID: 12086842
    [TBL] [Abstract][Full Text] [Related]  

  • 2. An oncolytic adenovirus selective for retinoblastoma tumor suppressor protein pathway-defective tumors: dependence on E1A, the E2F-1 promoter, and viral replication for selectivity and efficacy.
    Jakubczak JL; Ryan P; Gorziglia M; Clarke L; Hawkins LK; Hay C; Huang Y; Kaloss M; Marinov A; Phipps S; Pinkstaff A; Shirley P; Skripchenko Y; Stewart D; Forry-Schaudies S; Hallenbeck PL
    Cancer Res; 2003 Apr; 63(7):1490-9. PubMed ID: 12670895
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Selectively replicating adenoviruses targeting deregulated E2F activity are potent, systemic antitumor agents.
    Johnson L; Shen A; Boyle L; Kunich J; Pandey K; Lemmon M; Hermiston T; Giedlin M; McCormick F; Fattaey A
    Cancer Cell; 2002 May; 1(4):325-37. PubMed ID: 12086848
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Re-engineering adenovirus regulatory pathways to enhance oncolytic specificity and efficacy.
    Ramachandra M; Rahman A; Zou A; Vaillancourt M; Howe JA; Antelman D; Sugarman B; Demers GW; Engler H; Johnson D; Shabram P
    Nat Biotechnol; 2001 Nov; 19(11):1035-41. PubMed ID: 11689848
    [TBL] [Abstract][Full Text] [Related]  

  • 5. An E2F-responsive replication-selective adenovirus targeted to the defective cell cycle in cancer cells: potent antitumoral efficacy but no toxicity to normal cell.
    Tsukuda K; Wiewrodt R; Molnar-Kimber K; Jovanovic VP; Amin KM
    Cancer Res; 2002 Jun; 62(12):3438-47. PubMed ID: 12067986
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Infection of cells with replication deficient adenovirus induces cell cycle alterations and leads to downregulation of E2F-1.
    Kuhn H; Liebers U; Gessner C; Karawajew L; Ruppert V; Schumacher A; Witt C; Wolff G
    Biochim Biophys Acta; 2002 Jan; 1542(1-3):106-15. PubMed ID: 11853884
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Use of the E2F transcription factor by DNA tumor virus regulatory proteins.
    Cress WD; Nevins JR
    Curr Top Microbiol Immunol; 1996; 208():63-78. PubMed ID: 8575213
    [No Abstract]   [Full Text] [Related]  

  • 8. pRB, p107 and the regulation of the E2F transcription factor.
    Dyson N
    J Cell Sci Suppl; 1994; 18():81-7. PubMed ID: 7883798
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activity of the retinoblastoma family proteins, pRB, p107, and p130, during cellular proliferation and differentiation.
    Sidle A; Palaty C; Dirks P; Wiggan O; Kiess M; Gill RM; Wong AK; Hamel PA
    Crit Rev Biochem Mol Biol; 1996 Jun; 31(3):237-71. PubMed ID: 8817077
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of an ovine atadenovirus gene whose product activates the viral E2 promoter: possible involvement of E2F-1.
    Kümin D; Hofmann C; Uckert W; Both GW; Löser P
    Virology; 2004 Jan; 318(1):79-89. PubMed ID: 14972537
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product.
    Chellappan S; Kraus VB; Kroger B; Munger K; Howley PM; Phelps WC; Nevins JR
    Proc Natl Acad Sci U S A; 1992 May; 89(10):4549-53. PubMed ID: 1316611
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transcriptional inhibition by the retinoblastoma protein.
    Fattaey A; Helin K; Harlow E
    Philos Trans R Soc Lond B Biol Sci; 1993 Jun; 340(1293):333-6. PubMed ID: 8103936
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The E2F-family proteins induce distinct cell cycle regulatory factors in p16-arrested, U343 astrocytoma cells.
    Dirks PB; Rutka JT; Hubbard SL; Mondal S; Hamel PA
    Oncogene; 1998 Aug; 17(7):867-76. PubMed ID: 9780003
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Systemic toxicity-efficacy profile of ICOVIR-5, a potent and selective oncolytic adenovirus based on the pRB pathway.
    Cascallo M; Alonso MM; Rojas JJ; Perez-Gimenez A; Fueyo J; Alemany R
    Mol Ther; 2007 Sep; 15(9):1607-15. PubMed ID: 17579575
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth.
    Sellers WR; Novitch BG; Miyake S; Heith A; Otterson GA; Kaye FJ; Lassar AB; Kaelin WG
    Genes Dev; 1998 Jan; 12(1):95-106. PubMed ID: 9420334
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In vitro and in vivo activities of an oncolytic adenoviral vector designed to express GM-CSF.
    Bristol JA; Zhu M; Ji H; Mina M; Xie Y; Clarke L; Forry-Schaudies S; Ennist DL
    Mol Ther; 2003 Jun; 7(6):755-64. PubMed ID: 12788649
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Caspase activation and changes in Bcl-2 family member protein expression associated with E2F-1-mediated apoptosis in human esophageal cancer cells.
    Yang HL; Dong YB; Elliott MJ; Liu TJ; McMasters KM
    Clin Cancer Res; 2000 Apr; 6(4):1579-89. PubMed ID: 10778992
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Antitumor efficacy and tumor-selective replication with a single intravenous injection of OAS403, an oncolytic adenovirus dependent on two prevalent alterations in human cancer.
    Ryan PC; Jakubczak JL; Stewart DA; Hawkins LK; Cheng C; Clarke LM; Ganesh S; Hay C; Huang Y; Kaloss M; Marinov A; Phipps SS; Reddy PS; Shirley PS; Skripchenko Y; Xu L; Yang J; Forry-Schaudies S; Hallenbeck PL
    Cancer Gene Ther; 2004 Aug; 11(8):555-69. PubMed ID: 15232601
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F.
    Cao L; Faha B; Dembski M; Tsai LH; Harlow E; Dyson N
    Nature; 1992 Jan; 355(6356):176-9. PubMed ID: 1530885
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of the retinoblastoma (pRb)-E2F/DP pathway in cancer chemopreventive effects of green tea polyphenol epigallocatechin-3-gallate.
    Ahmad N; Adhami VM; Gupta S; Cheng P; Mukhtar H
    Arch Biochem Biophys; 2002 Feb; 398(1):125-31. PubMed ID: 11811957
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.