BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

253 related articles for article (PubMed ID: 12086891)

  • 1. A role for common fragile site induction in amplification of human oncogenes.
    Hellman A; Zlotorynski E; Scherer SW; Cheung J; Vincent JB; Smith DI; Trakhtenbrot L; Kerem B
    Cancer Cell; 2002 Feb; 1(1):89-97. PubMed ID: 12086891
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Expression of fragile sites triggers intrachromosomal mammalian gene amplification and sets boundaries to early amplicons.
    Coquelle A; Pipiras E; Toledo F; Buttin G; Debatisse M
    Cell; 1997 Apr; 89(2):215-25. PubMed ID: 9108477
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Initiation of the breakage-fusion-bridge mechanism through common fragile site activation in human breast cancer cells: the model of PIP gene duplication from a break at FRA7I.
    Ciullo M; Debily MA; Rozier L; Autiero M; Billault A; Mayau V; El Marhomy S; Guardiola J; Bernheim A; Coullin P; Piatier-Tonneau D; Debatisse M
    Hum Mol Genet; 2002 Nov; 11(23):2887-94. PubMed ID: 12393800
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Alternative mechanisms of gene amplification in human cancers.
    Kuwahara Y; Tanabe C; Ikeuchi T; Aoyagi K; Nishigaki M; Sakamoto H; Hoshinaga K; Yoshida T; Sasaki H; Terada M
    Genes Chromosomes Cancer; 2004 Oct; 41(2):125-32. PubMed ID: 15287025
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of the human/mouse syntenic common fragile site FRA7K/Fra12C1--relation of FRA7K and other human common fragile sites on chromosome 7 to evolutionary breakpoints.
    Helmrich A; Stout-Weider K; Matthaei A; Hermann K; Heiden T; Schrock E
    Int J Cancer; 2007 Jan; 120(1):48-54. PubMed ID: 17039484
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Candidate tumor suppressor genes at FRA7G are coamplified with MET and do not suppress malignancy in a gastric cancer.
    Han SY; Druck T; Huebner K
    Genomics; 2003 Feb; 81(2):105-7. PubMed ID: 12620387
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hgfr/Met oncogene acts as target for gene amplification in DMBA-induced rat sarcomas: free chromatin fluorescence in situ hybridization analysis of amplicon arrays in homogeneously staining regions.
    Helou K; Walentinsson A; Kost-Alimova M; Levan G
    Genes Chromosomes Cancer; 2001 Apr; 30(4):416-20. PubMed ID: 11241796
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Common fragile sites associated with the breakpoints of chromosomal aberrations in hematologic neoplasms.
    Gümüş G; Sunguroğlu A; Tükün A; Sayin DB; Bökesoy I
    Cancer Genet Cytogenet; 2002 Mar; 133(2):168-71. PubMed ID: 11943347
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Evidence for a novel mechanism for gene amplification in multiple myeloma: 1q12 pericentromeric heterochromatin mediates breakage-fusion-bridge cycles of a 1q12 approximately 23 amplicon.
    Sawyer JR; Tian E; Thomas E; Koller M; Stangeby C; Sammartino G; Goosen L; Swanson C; Binz RL; Barlogie B; Shaughnessy J
    Br J Haematol; 2009 Nov; 147(4):484-94. PubMed ID: 19744130
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Stably transfected common fragile site sequences exhibit instability at ectopic sites.
    Ragland RL; Glynn MW; Arlt MF; Glover TW
    Genes Chromosomes Cancer; 2008 Oct; 47(10):860-72. PubMed ID: 18615677
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of unstable sequences within the common fragile site at 3p14.2: implications for the mechanism of deletions within fragile histidine triad gene/common fragile site at 3p14.2 in tumors.
    Corbin S; Neilly ME; Espinosa R; Davis EM; McKeithan TW; Le Beau MM
    Cancer Res; 2002 Jun; 62(12):3477-84. PubMed ID: 12067991
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Gene amplification mechanisms: the role of fragile sites.
    Debatisse M; Coquelle A; Toledo F; Buttin G
    Recent Results Cancer Res; 1998; 154():216-26. PubMed ID: 10027002
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chromosomal fragile site FRA16D and DNA instability in cancer.
    Mangelsdorf M; Ried K; Woollatt E; Dayan S; Eyre H; Finnis M; Hobson L; Nancarrow J; Venter D; Baker E; Richards RI
    Cancer Res; 2000 Mar; 60(6):1683-9. PubMed ID: 10749140
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Congenital chromosome breakage clusters within Giemsa-light bands and identifies sites of chromatin instability.
    Koduru P; Chaganti R
    Cytogenet Cell Genet; 1988; 49(4):269-74. PubMed ID: 3248384
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A consistent pattern of RIN1 rearrangements in oral squamous cell carcinoma cell lines supports a breakage-fusion-bridge cycle model for 11q13 amplification.
    Shuster MI; Han L; Le Beau MM; Davis E; Sawicki M; Lese CM; Park NH; Colicelli J; Gollin SM
    Genes Chromosomes Cancer; 2000 Jun; 28(2):153-63. PubMed ID: 10825000
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Oncogenes create a unique landscape of fragile sites.
    Miron K; Golan-Lev T; Dvir R; Ben-David E; Kerem B
    Nat Commun; 2015 May; 6():7094. PubMed ID: 25959793
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Translocation breakpoints in FHIT and FRA3B in both homologs of chromosome 3 in an esophageal adenocarcinoma.
    Fang JM; Arlt MF; Burgess AC; Dagenais SL; Beer DG; Glover TW
    Genes Chromosomes Cancer; 2001 Mar; 30(3):292-8. PubMed ID: 11170287
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Breakages at common fragile sites set boundaries of amplified regions in two leukemia cell lines K562 - Molecular characterization of FRA2H and localization of a new CFS FRA2S.
    Pelliccia F; Bosco N; Rocchi A
    Cancer Lett; 2010 Dec; 299(1):37-44. PubMed ID: 20851513
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Fish mapping of YAC clones at human chromosomal band 7q31.2: identification of YACS spanning FRA7G within the common region of LOH in breast and prostate cancer.
    Huang H; Qian C; Jenkins RB; Smith DI
    Genes Chromosomes Cancer; 1998 Feb; 21(2):152-9. PubMed ID: 9491327
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A new role for hypoxia in tumor progression: induction of fragile site triggering genomic rearrangements and formation of complex DMs and HSRs.
    Coquelle A; Toledo F; Stern S; Bieth A; Debatisse M
    Mol Cell; 1998 Aug; 2(2):259-65. PubMed ID: 9734364
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.