These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

174 related articles for article (PubMed ID: 12086970)

  • 1. Maturity-onset diabetes of the young caused by a balanced translocation where the 20q12 break point results in disruption upstream of the coding region of hepatocyte nuclear factor-4alpha (HNF4A) gene.
    Gloyn AL; Ellard S; Shepherd M; Howell RT; Parry EM; Jefferson A; Levy ER; Hattersley AT
    Diabetes; 2002 Jul; 51(7):2329-33. PubMed ID: 12086970
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A distant upstream promoter of the HNF-4alpha gene connects the transcription factors involved in maturity-onset diabetes of the young.
    Thomas H; Jaschkowitz K; Bulman M; Frayling TM; Mitchell SM; Roosen S; Lingott-Frieg A; Tack CJ; Ellard S; Ryffel GU; Hattersley AT
    Hum Mol Genet; 2001 Sep; 10(19):2089-97. PubMed ID: 11590126
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Genetic evidence that HNF-1alpha-dependent transcriptional control of HNF-4alpha is essential for human pancreatic beta cell function.
    Hansen SK; Párrizas M; Jensen ML; Pruhova S; Ek J; Boj SF; Johansen A; Maestro MA; Rivera F; Eiberg H; Andel M; Lebl J; Pedersen O; Ferrer J; Hansen T
    J Clin Invest; 2002 Sep; 110(6):827-33. PubMed ID: 12235114
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1).
    Yamagata K; Furuta H; Oda N; Kaisaki PJ; Menzel S; Cox NJ; Fajans SS; Signorini S; Stoffel M; Bell GI
    Nature; 1996 Dec; 384(6608):458-60. PubMed ID: 8945471
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Functional study of the E276Q mutant hepatocyte nuclear factor-4alpha found in type 1 maturity-onset diabetes of the young: impaired synergy with chicken ovalbumin upstream promoter transcription factor II on the hepatocyte nuclear factor-1 promoter.
    Suaud L; Hemimou Y; Formstecher P; Laine B
    Diabetes; 1999 May; 48(5):1162-7. PubMed ID: 10331424
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mutations in the genes for hepatocyte nuclear factor (HNF)-1alpha, -4alpha, -1beta, and -3beta; the dimerization cofactor of HNF-1; and insulin promoter factor 1 are not common causes of early-onset type 2 diabetes in Pima Indians.
    Baier LJ; Permana PA; Traurig M; Dobberfuhl A; Wiedrich C; Sutherland J; Thuillez P; Luczy-Bachman G; Hara M; Horikawa Y; Hinokio Y; Hanson RL; Bogardus C
    Diabetes Care; 2000 Mar; 23(3):302-4. PubMed ID: 10868855
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel Phe75fsdelT mutation in the hepatocyte nuclear factor-4alpha gene in a Danish pedigree with maturity-onset diabetes of the young.
    Møller AM; Dalgaard LT; Ambye L; Hansen L; Schmitz O; Hansen T; Pedersen O
    J Clin Endocrinol Metab; 1999 Jan; 84(1):367-9. PubMed ID: 9920109
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Maturity-onset diabetes of the young due to a mutation in the hepatocyte nuclear factor-4 alpha binding site in the promoter of the hepatocyte nuclear factor-1 alpha gene.
    Gragnoli C; Lindner T; Cockburn BN; Kaisaki PJ; Gragnoli F; Marozzi G; Bell GI
    Diabetes; 1997 Oct; 46(10):1648-51. PubMed ID: 9313764
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hepatic function in a family with a nonsense mutation (R154X) in the hepatocyte nuclear factor-4alpha/MODY1 gene.
    Lindner T; Gragnoli C; Furuta H; Cockburn BN; Petzold C; Rietzsch H; Weiss U; Schulze J; Bell GI
    J Clin Invest; 1997 Sep; 100(6):1400-5. PubMed ID: 9294105
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A missense mutation in hepatocyte nuclear factor-4 alpha, resulting in a reduced transactivation activity, in human late-onset non-insulin-dependent diabetes mellitus.
    Hani EH; Suaud L; Boutin P; Chèvre JC; Durand E; Philippi A; Demenais F; Vionnet N; Furuta H; Velho G; Bell GI; Laine B; Froguel P
    J Clin Invest; 1998 Feb; 101(3):521-6. PubMed ID: 9449683
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Different genes, different diabetes: lessons from maturity-onset diabetes of the young.
    Stride A; Hattersley AT
    Ann Med; 2002; 34(3):207-16. PubMed ID: 12173691
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [Mutations in the genes of the HNF-family cause maturity-onset diabetes of the young (MODY)].
    Takeda J
    Nihon Rinsho; 1998 Sep; 56(9):2419-26. PubMed ID: 9780731
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Exclusion of the hepatocyte nuclear factor 4alpha as a candidate gene for late-onset NIDDM linked with chromosome 20q.
    Malecki MT; Antonellis A; Casey P; Ji L; Wantman M; Warram JH; Krolewski AS
    Diabetes; 1998 Jun; 47(6):970-2. PubMed ID: 9604877
    [No Abstract]   [Full Text] [Related]  

  • 14. High frequency of mutations in MODY and mitochondrial genes in Scandinavian patients with familial early-onset diabetes.
    Lehto M; Wipemo C; Ivarsson SA; Lindgren C; Lipsanen-Nyman M; Weng J; Wibell L; Widén E; Tuomi T; Groop L
    Diabetologia; 1999 Sep; 42(9):1131-7. PubMed ID: 10447526
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A missense mutation in the hepatocyte nuclear factor 4 alpha gene in a UK pedigree with maturity-onset diabetes of the young.
    Bulman MP; Dronsfield MJ; Frayling T; Appleton M; Bain SC; Ellard S; Hattersley AT
    Diabetologia; 1997 Jul; 40(7):859-62. PubMed ID: 9243109
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The role of transcription factors in maturity-onset diabetes of the young.
    Mitchell SM; Frayling TM
    Mol Genet Metab; 2002; 77(1-2):35-43. PubMed ID: 12359128
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of new mutations in the hepatocyte nuclear factor 4alpha gene among families with early onset Type 2 diabetes mellitus.
    Malecki MT; Yang Y; Antonellis A; Curtis S; Warram JH; Krolewski AS
    Diabet Med; 1999 Mar; 16(3):193-200. PubMed ID: 10227563
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A common polymorphism in the upstream promoter region of the hepatocyte nuclear factor-4 alpha gene on chromosome 20q is associated with type 2 diabetes and appears to contribute to the evidence for linkage in an ashkenazi jewish population.
    Love-Gregory LD; Wasson J; Ma J; Jin CH; Glaser B; Suarez BK; Permutt MA
    Diabetes; 2004 Apr; 53(4):1134-40. PubMed ID: 15047632
    [TBL] [Abstract][Full Text] [Related]  

  • 19. No diabetes-associated mutations in the coding region of the hepatocyte nuclear factor-4gamma gene (HNF4G) in Japanese patients with MODY.
    Hara M; Wang X; Paz VP; Cox NJ; Iwasaki N; Ogata M; Iwamoto Y; Bell GI
    Diabetologia; 2000 Aug; 43(8):1064-9. PubMed ID: 10990086
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Large Family With Maturity-Onset Diabetes of the Young and a Novel V121I Mutation in HNF4A.
    Monney CT; Kaltenrieder V; Cousin P; Bonny C; Schorderet DF
    Hum Mutat; 2002 Sep; 20(3):230-1. PubMed ID: 12203996
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.