BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

213 related articles for article (PubMed ID: 12087126)

  • 1. Distinct domains of splicing factor Prp8 mediate different aspects of spliceosome activation.
    Kuhn AN; Reichl EM; Brow DA
    Proc Natl Acad Sci U S A; 2002 Jul; 99(14):9145-9. PubMed ID: 12087126
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Suppressors of a cold-sensitive mutation in yeast U4 RNA define five domains in the splicing factor Prp8 that influence spliceosome activation.
    Kuhn AN; Brow DA
    Genetics; 2000 Aug; 155(4):1667-82. PubMed ID: 10924465
    [TBL] [Abstract][Full Text] [Related]  

  • 3. An unanticipated early function of DEAD-box ATPase Prp28 during commitment to splicing is modulated by U5 snRNP protein Prp8.
    Price AM; Görnemann J; Guthrie C; Brow DA
    RNA; 2014 Jan; 20(1):46-60. PubMed ID: 24231520
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Splicing factor Prp8 governs U4/U6 RNA unwinding during activation of the spliceosome.
    Kuhn AN; Li Z; Brow DA
    Mol Cell; 1999 Jan; 3(1):65-75. PubMed ID: 10024880
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Roles of PRP8 protein in the assembly of splicing complexes.
    Brown JD; Beggs JD
    EMBO J; 1992 Oct; 11(10):3721-9. PubMed ID: 1396567
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Prp8 RNase H-like domain inhibits Brr2-mediated U4/U6 snRNA unwinding by blocking Brr2 loading onto the U4 snRNA.
    Mozaffari-Jovin S; Santos KF; Hsiao HH; Will CL; Urlaub H; Wahl MC; Lührmann R
    Genes Dev; 2012 Nov; 26(21):2422-34. PubMed ID: 23124066
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The U5 snRNA internal loop 1 is a platform for Brr2, Snu114 and Prp8 protein binding during U5 snRNP assembly.
    Nancollis V; Ruckshanthi JP; Frazer LN; O'Keefe RT
    J Cell Biochem; 2013 Dec; 114(12):2770-84. PubMed ID: 23857713
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ATP-dependent unwinding of U4/U6 snRNAs by the Brr2 helicase requires the C terminus of Prp8.
    Maeder C; Kutach AK; Guthrie C
    Nat Struct Mol Biol; 2009 Jan; 16(1):42-8. PubMed ID: 19098916
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Allele-specific genetic interactions between Prp8 and RNA active site residues suggest a function for Prp8 at the catalytic core of the spliceosome.
    Collins CA; Guthrie C
    Genes Dev; 1999 Aug; 13(15):1970-82. PubMed ID: 10444595
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Functional contacts with a range of splicing proteins suggest a central role for Brr2p in the dynamic control of the order of events in spliceosomes of Saccharomyces cerevisiae.
    van Nues RW; Beggs JD
    Genetics; 2001 Apr; 157(4):1451-67. PubMed ID: 11290703
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Functional interactions of Prp8 with both splice sites at the spliceosomal catalytic center.
    Siatecka M; Reyes JL; Konarska MM
    Genes Dev; 1999 Aug; 13(15):1983-93. PubMed ID: 10444596
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dissection of Prp8 protein defines multiple interactions with crucial RNA sequences in the catalytic core of the spliceosome.
    Turner IA; Norman CM; Churcher MJ; Newman AJ
    RNA; 2006 Mar; 12(3):375-86. PubMed ID: 16431982
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Extensive interactions of PRP8 protein with the 5' and 3' splice sites during splicing suggest a role in stabilization of exon alignment by U5 snRNA.
    Teigelkamp S; Newman AJ; Beggs JD
    EMBO J; 1995 Jun; 14(11):2602-12. PubMed ID: 7781612
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Assembly of Snu114 into U5 snRNP requires Prp8 and a functional GTPase domain.
    Brenner TJ; Guthrie C
    RNA; 2006 May; 12(5):862-71. PubMed ID: 16540695
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Brr2 plays a role in spliceosomal activation in addition to U4/U6 unwinding.
    Zhang L; Li X; Hill RC; Qiu Y; Zhang W; Hansen KC; Zhao R
    Nucleic Acids Res; 2015 Mar; 43(6):3286-97. PubMed ID: 25670679
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CEF1/CDC5 alleles modulate transitions between catalytic conformations of the spliceosome.
    Query CC; Konarska MM
    RNA; 2012 May; 18(5):1001-13. PubMed ID: 22408182
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure of a spliceosome remodelled for exon ligation.
    Fica SM; Oubridge C; Galej WP; Wilkinson ME; Bai XC; Newman AJ; Nagai K
    Nature; 2017 Feb; 542(7641):377-380. PubMed ID: 28076345
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Suppression of multiple substrate mutations by spliceosomal prp8 alleles suggests functional correlations with ribosomal ambiguity mutants.
    Query CC; Konarska MM
    Mol Cell; 2004 May; 14(3):343-54. PubMed ID: 15125837
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Opposing classes of prp8 alleles modulate the transition between the catalytic steps of pre-mRNA splicing.
    Liu L; Query CC; Konarska MM
    Nat Struct Mol Biol; 2007 Jun; 14(6):519-26. PubMed ID: 17486100
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutations in the U5 snRNA result in altered splicing of subsets of pre-mRNAs and reduced stability of Prp8.
    Kershaw CJ; Barrass JD; Beggs JD; O'Keefe RT
    RNA; 2009 Jul; 15(7):1292-304. PubMed ID: 19447917
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.