BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

215 related articles for article (PubMed ID: 12087126)

  • 21. Crystal structure of the beta-finger domain of Prp8 reveals analogy to ribosomal proteins.
    Yang K; Zhang L; Xu T; Heroux A; Zhao R
    Proc Natl Acad Sci U S A; 2008 Sep; 105(37):13817-22. PubMed ID: 18779563
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Structural toggle in the RNaseH domain of Prp8 helps balance splicing fidelity and catalytic efficiency.
    Mayerle M; Raghavan M; Ledoux S; Price A; Stepankiw N; Hadjivassiliou H; Moehle EA; Mendoza SD; Pleiss JA; Guthrie C; Abelson J
    Proc Natl Acad Sci U S A; 2017 May; 114(18):4739-4744. PubMed ID: 28416677
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Cryo-EM structure of the spliceosome immediately after branching.
    Galej WP; Wilkinson ME; Fica SM; Oubridge C; Newman AJ; Nagai K
    Nature; 2016 Sep; 537(7619):197-201. PubMed ID: 27459055
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The EF-G-like GTPase Snu114p regulates spliceosome dynamics mediated by Brr2p, a DExD/H box ATPase.
    Small EC; Leggett SR; Winans AA; Staley JP
    Mol Cell; 2006 Aug; 23(3):389-99. PubMed ID: 16885028
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The architecture of the spliceosomal U4/U6.U5 tri-snRNP.
    Nguyen TH; Galej WP; Bai XC; Savva CG; Newman AJ; Scheres SH; Nagai K
    Nature; 2015 Jul; 523(7558):47-52. PubMed ID: 26106855
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Genetic analysis reveals a role for the C terminus of the Saccharomyces cerevisiae GTPase Snu114 during spliceosome activation.
    Brenner TJ; Guthrie C
    Genetics; 2005 Jul; 170(3):1063-80. PubMed ID: 15911574
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Analysis of synthetic lethality reveals genetic interactions between the GTPase Snu114p and snRNAs in the catalytic core of the Saccharomyces cerevisiae spliceosome.
    Frazer LN; Lovell SC; O'Keefe RT
    Genetics; 2009 Oct; 183(2):497-515-1SI-4SI. PubMed ID: 19620389
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Functional interactions between Prp8, Prp18, Slu7, and U5 snRNA during the second step of pre-mRNA splicing.
    Aronova A; Bacíková D; Crotti LB; Horowitz DS; Schwer B
    RNA; 2007 Sep; 13(9):1437-44. PubMed ID: 17626844
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Multiple genetic and biochemical interactions of Brr2, Prp8, Prp31, Prp1 and Prp4 kinase suggest a function in the control of the activation of spliceosomes in Schizosaccharomyces pombe.
    Bottner CA; Schmidt H; Vogel S; Michele M; Käufer NF
    Curr Genet; 2005 Sep; 48(3):151-61. PubMed ID: 16133344
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Motifs IV and V in the DEAH box splicing factor Prp22 are important for RNA unwinding, and helicase-defective Prp22 mutants are suppressed by Prp8.
    Schneider S; Campodonico E; Schwer B
    J Biol Chem; 2004 Mar; 279(10):8617-26. PubMed ID: 14688266
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The large N-terminal region of the Brr2 RNA helicase guides productive spliceosome activation.
    Absmeier E; Wollenhaupt J; Mozaffari-Jovin S; Becke C; Lee CT; Preussner M; Heyd F; Urlaub H; Lührmann R; Santos KF; Wahl MC
    Genes Dev; 2015 Dec; 29(24):2576-87. PubMed ID: 26637280
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Interaction of the yeast splicing factor PRP8 with substrate RNA during both steps of splicing.
    Teigelkamp S; Whittaker E; Beggs JD
    Nucleic Acids Res; 1995 Feb; 23(3):320-6. PubMed ID: 7885825
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Mutagenesis of the yeast gene PRP8 reveals domains governing the specificity and fidelity of 3' splice site selection.
    Umen JG; Guthrie C
    Genetics; 1996 Jun; 143(2):723-39. PubMed ID: 8725222
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Comprehensive in vivo RNA-binding site analyses reveal a role of Prp8 in spliceosomal assembly.
    Li X; Zhang W; Xu T; Ramsey J; Zhang L; Hill R; Hansen KC; Hesselberth JR; Zhao R
    Nucleic Acids Res; 2013 Apr; 41(6):3805-18. PubMed ID: 23393194
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Localization of Prp8, Brr2, Snu114 and U4/U6 proteins in the yeast tri-snRNP by electron microscopy.
    Häcker I; Sander B; Golas MM; Wolf E; Karagöz E; Kastner B; Stark H; Fabrizio P; Lührmann R
    Nat Struct Mol Biol; 2008 Nov; 15(11):1206-12. PubMed ID: 18953335
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Genetic interactions between the yeast RNA helicase homolog Prp16 and spliceosomal snRNAs identify candidate ligands for the Prp16 RNA-dependent ATPase.
    Madhani HD; Guthrie C
    Genetics; 1994 Jul; 137(3):677-87. PubMed ID: 8088513
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Structural dynamics of the N-terminal domain and the Switch loop of Prp8 during spliceosome assembly and activation.
    Jia X; Sun C
    Nucleic Acids Res; 2018 May; 46(8):3833-3840. PubMed ID: 29635373
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Retinitis Pigmentosa Mutations in Bad Response to Refrigeration 2 (Brr2) Impair ATPase and Helicase Activity.
    Ledoux S; Guthrie C
    J Biol Chem; 2016 Jun; 291(23):11954-65. PubMed ID: 27072132
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Cwc21p promotes the second step conformation of the spliceosome and modulates 3' splice site selection.
    Gautam A; Grainger RJ; Vilardell J; Barrass JD; Beggs JD
    Nucleic Acids Res; 2015 Mar; 43(6):3309-17. PubMed ID: 25740649
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Activation of Prp28 ATPase by phosphorylated Npl3 at a critical step of spliceosome remodeling.
    Yeh FL; Chang SL; Ahmed GR; Liu HI; Tung L; Yeh CS; Lanier LS; Maeder C; Lin CM; Tsai SC; Hsiao WY; Chang WH; Chang TH
    Nat Commun; 2021 May; 12(1):3082. PubMed ID: 34035302
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.