BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

263 related articles for article (PubMed ID: 12093292)

  • 1. Role of the N-terminus of epidermal growth factor in ErbB-2/ErbB-3 binding studied by phage display.
    Stortelers C; Souriau C; van Liempt E; van de Poll ML; van Zoelen EJ
    Biochemistry; 2002 Jul; 41(27):8732-41. PubMed ID: 12093292
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Epidermal growth factor contains both positive and negative determinants for interaction with ErbB-2/ErbB-3 heterodimers.
    Stortelers C; van De Poll ML; Lenferink AE; Gadellaa MM; van Zoelen C; van Zoelen EJ
    Biochemistry; 2002 Apr; 41(13):4292-301. PubMed ID: 11914075
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Selective formation of ErbB-2/ErbB-3 heterodimers depends on the ErbB-3 affinity of epidermal growth factor-like ligands.
    Stortelers C; van der Woning SP; Jacobs-Oomen S; Wingens M; van Zoelen EJ
    J Biol Chem; 2003 Apr; 278(14):12055-63. PubMed ID: 12556529
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Negative constraints underlie the ErbB specificity of epidermal growth factor-like ligands.
    van der Woning SP; van Rotterdam W; Nabuurs SB; Venselaar H; Jacobs-Oomen S; Wingens M; Vriend G; Stortelers C; van Zoelen EJ
    J Biol Chem; 2006 Dec; 281(52):40033-40. PubMed ID: 17032651
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bivalence of EGF-like ligands drives the ErbB signaling network.
    Tzahar E; Pinkas-Kramarski R; Moyer JD; Klapper LN; Alroy I; Levkowitz G; Shelly M; Henis S; Eisenstein M; Ratzkin BJ; Sela M; Andrews GC; Yarden Y
    EMBO J; 1997 Aug; 16(16):4938-50. PubMed ID: 9305636
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The extracellular domain of the epidermal growth factor receptor. Studies on the affinity and stoichiometry of binding, receptor dimerization and a binding-domain mutant.
    Brown PM; Debanne MT; Grothe S; Bergsma D; Caron M; Kay C; O'Connor-McCourt MD
    Eur J Biochem; 1994 Oct; 225(1):223-33. PubMed ID: 7925442
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of the high affinity binding site of transforming growth factor-alpha (TGF-alpha) for the chicken epidermal growth factor (EGF) receptor using EGF/TGF-alpha chimeras.
    Kramer RH; Lenferink AE; van Bueren-Koornneef IL; van der Meer A; van de Poll ML; van Zoelen EJ
    J Biol Chem; 1994 Mar; 269(12):8708-11. PubMed ID: 8132599
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The functional importance of hydrophobicity of the tyrosine at position 13 of human epidermal growth factor in receptor binding.
    Tadaki DK; Niyogi SK
    J Biol Chem; 1993 May; 268(14):10114-9. PubMed ID: 8486681
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The oncogenic ErbB-2/ErbB-3 heterodimer is a surrogate receptor of the epidermal growth factor and betacellulin.
    Pinkas-Kramarski R; Lenferink AE; Bacus SS; Lyass L; van de Poll ML; Klapper LN; Tzahar E; Sela M; van Zoelen EJ; Yarden Y
    Oncogene; 1998 Mar; 16(10):1249-58. PubMed ID: 9546426
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A single amino acid exchange, Arg-45 to Ala, generates an epidermal growth factor (EGF) mutant with high affinity for the chicken EGF receptor.
    van de Poll ML; Lenferink AE; van Vugt MJ; Jacobs JJ; Janssen JW; Joldersma M; van Zoelen EJ
    J Biol Chem; 1995 Sep; 270(38):22337-43. PubMed ID: 7673217
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural analysis of an epidermal growth factor/transforming growth factor-alpha chimera with unique ErbB binding specificity.
    Wingens M; Walma T; van Ingen H; Stortelers C; van Leeuwen JE; van Zoelen EJ; Vuister GW
    J Biol Chem; 2003 Oct; 278(40):39114-23. PubMed ID: 12869572
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Binding specificities and affinities of egf domains for ErbB receptors.
    Jones JT; Akita RW; Sliwkowski MX
    FEBS Lett; 1999 Mar; 447(2-3):227-31. PubMed ID: 10214951
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Contribution of the transforming growth factor alpha B-loop beta-sheet to binding and activation of the epidermal growth factor receptor.
    Richter A; Drummond DR; MacGarvie J; Puddicombe SM; Chamberlin SG; Davies DE
    J Biol Chem; 1995 Jan; 270(4):1612-6. PubMed ID: 7829492
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Replacement of N-terminal portions of TGF-alpha with corresponding heregulin sequences affects ligand-induced receptor signaling and intoxication of tumor cells by chimeric growth-factor toxins.
    Schmidt M; Wels W
    Int J Cancer; 2002 Jan; 97(3):349-56. PubMed ID: 11774287
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Selection of heregulin variants having higher affinity for the ErbB3 receptor by monovalent phage display.
    Ballinger MD; Jones JT; Lofgren JA; Fairbrother WJ; Akita RW; Sliwkowski MX; Wells JA
    J Biol Chem; 1998 May; 273(19):11675-84. PubMed ID: 9565588
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Epidermal growth factor mutant with wild-type affinity for both ErbB1 and ErbB3.
    Wingens M; Jacobs-Oomen S; van der Woning SP; Stortelers C; van Zoelen EJ
    Biochemistry; 2006 Apr; 45(14):4703-10. PubMed ID: 16584205
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Insights into the evolution of the ErbB receptor family and their ligands from sequence analysis.
    Stein RA; Staros JV
    BMC Evol Biol; 2006 Oct; 6():79. PubMed ID: 17026767
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Binding interaction of the heregulinbeta egf domain with ErbB3 and ErbB4 receptors assessed by alanine scanning mutagenesis.
    Jones JT; Ballinger MD; Pisacane PI; Lofgren JA; Fitzpatrick VD; Fairbrother WJ; Wells JA; Sliwkowski MX
    J Biol Chem; 1998 May; 273(19):11667-74. PubMed ID: 9565587
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of a determinant of epidermal growth factor receptor ligand-binding specificity using a truncated, high-affinity form of the ectodomain.
    Elleman TC; Domagala T; McKern NM; Nerrie M; Lönnqvist B; Adams TE; Lewis J; Lovrecz GO; Hoyne PA; Richards KM; Howlett GJ; Rothacker J; Jorissen RN; Lou M; Garrett TP; Burgess AW; Nice EC; Ward CW
    Biochemistry; 2001 Jul; 40(30):8930-9. PubMed ID: 11467954
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Rational optimization of a bispecific ligand trap targeting EGF receptor family ligands.
    Jin P; Zhang J; Beryt M; Turin L; Brdlik C; Feng Y; Bai X; Liu J; Jorgensen B; Shepard HM
    Mol Med; 2009; 15(1-2):11-20. PubMed ID: 19048033
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.