132 related articles for article (PubMed ID: 12094239)
1. LKB1--a master tumour suppressor of the small intestine and beyond.
Yoo LI; Chung DC; Yuan J
Nat Rev Cancer; 2002 Jul; 2(7):529-35. PubMed ID: 12094239
[No Abstract] [Full Text] [Related]
2. The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death.
Karuman P; Gozani O; Odze RD; Zhou XC; Zhu H; Shaw R; Brien TP; Bozzuto CD; Ooi D; Cantley LC; Yuan J
Mol Cell; 2001 Jun; 7(6):1307-19. PubMed ID: 11430832
[TBL] [Abstract][Full Text] [Related]
3. Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation.
Bardeesy N; Sinha M; Hezel AF; Signoretti S; Hathaway NA; Sharpless NE; Loda M; Carrasco DR; DePinho RA
Nature; 2002 Sep; 419(6903):162-7. PubMed ID: 12226664
[TBL] [Abstract][Full Text] [Related]
4. Functional analysis of LKB1/STK11 mutants and two aberrant isoforms found in Peutz-Jeghers Syndrome patients.
Boudeau J; Kieloch A; Alessi DR; Stella A; Guanti G; Resta N
Hum Mutat; 2003 Feb; 21(2):172. PubMed ID: 12552571
[TBL] [Abstract][Full Text] [Related]
5. LKB1 interacts with and phosphorylates PTEN: a functional link between two proteins involved in cancer predisposing syndromes.
Mehenni H; Lin-Marq N; Buchet-Poyau K; Reymond A; Collart MA; Picard D; Antonarakis SE
Hum Mol Genet; 2005 Aug; 14(15):2209-19. PubMed ID: 15987703
[TBL] [Abstract][Full Text] [Related]
6. De novo germline mutation in the serine-threonine kinase STK11/LKB1 gene associated with Peutz-Jeghers syndrome.
Hernan I; Roig I; Martin B; Gamundi MJ; Martinez-Gimeno M; Carballo M
Clin Genet; 2004 Jul; 66(1):58-62. PubMed ID: 15200509
[TBL] [Abstract][Full Text] [Related]
7. Mutation of Lkb1 and p53 genes exert a cooperative effect on tumorigenesis.
Wei C; Amos CI; Stephens LC; Campos I; Deng JM; Behringer RR; Rashid A; Frazier ML
Cancer Res; 2005 Dec; 65(24):11297-303. PubMed ID: 16357136
[TBL] [Abstract][Full Text] [Related]
8. Functional analysis of Peutz-Jeghers mutations reveals that the LKB1 C-terminal region exerts a crucial role in regulating both the AMPK pathway and the cell polarity.
Forcet C; Etienne-Manneville S; Gaude H; Fournier L; Debilly S; Salmi M; Baas A; Olschwang S; Clevers H; Billaud M
Hum Mol Genet; 2005 May; 14(10):1283-92. PubMed ID: 15800014
[TBL] [Abstract][Full Text] [Related]
9. STK11/LKB1 germline mutations in the first Peutz-Jeghers syndrome patients identified in Slovakia.
Bartosova Z; Zavodna K; Krivulcik T; Usak J; Mlkva I; Kruzliak T; Hromec J; Usakova V; Kopecka I; Veres P; Bartosova Z; Bujalkova M
Neoplasma; 2007; 54(2):101-7. PubMed ID: 17319781
[TBL] [Abstract][Full Text] [Related]
10. Accelerated onsets of gastric hamartomas and hepatic adenomas/carcinomas in Lkb1+/-p53-/- compound mutant mice.
Takeda H; Miyoshi H; Kojima Y; Oshima M; Taketo MM
Oncogene; 2006 Mar; 25(12):1816-20. PubMed ID: 16278673
[TBL] [Abstract][Full Text] [Related]
11. LKB1; linking cell structure and tumor suppression.
Hezel AF; Bardeesy N
Oncogene; 2008 Nov; 27(55):6908-19. PubMed ID: 19029933
[TBL] [Abstract][Full Text] [Related]
12. Genetic screening for Peutz-Jeghers syndrome.
Ballhausen WG; Günther K
Expert Rev Mol Diagn; 2003 Jul; 3(4):471-9. PubMed ID: 12877386
[TBL] [Abstract][Full Text] [Related]
13. LKB1 and AMPK family signaling: the intimate link between cell polarity and energy metabolism.
Jansen M; Ten Klooster JP; Offerhaus GJ; Clevers H
Physiol Rev; 2009 Jul; 89(3):777-98. PubMed ID: 19584313
[TBL] [Abstract][Full Text] [Related]
14. Stability of the Peutz-Jeghers syndrome kinase LKB1 requires its binding to the molecular chaperones Hsp90/Cdc37.
Nony P; Gaude H; Rossel M; Fournier L; Rouault JP; Billaud M
Oncogene; 2003 Dec; 22(57):9165-75. PubMed ID: 14668798
[TBL] [Abstract][Full Text] [Related]
15. Dysregulation of HIF and VEGF is a unifying feature of the familial hamartoma syndromes.
Brugarolas J; Kaelin WG
Cancer Cell; 2004 Jul; 6(1):7-10. PubMed ID: 15261137
[TBL] [Abstract][Full Text] [Related]
16. LKB1 is recruited to the p21/WAF1 promoter by p53 to mediate transcriptional activation.
Zeng PY; Berger SL
Cancer Res; 2006 Nov; 66(22):10701-8. PubMed ID: 17108107
[TBL] [Abstract][Full Text] [Related]
17. LKB1: a sweet side to Peutz-Jeghers syndrome?
Carling D
Trends Mol Med; 2006 Apr; 12(4):144-7. PubMed ID: 16530014
[TBL] [Abstract][Full Text] [Related]
18. LKB1 signaling in mesenchymal cells required for suppression of gastrointestinal polyposis.
Katajisto P; Vaahtomeri K; Ekman N; Ventelä E; Ristimäki A; Bardeesy N; Feil R; DePinho RA; Mäkelä TP
Nat Genet; 2008 Apr; 40(4):455-9. PubMed ID: 18311138
[TBL] [Abstract][Full Text] [Related]
19. A novel germline mutation of the LKB1 gene in a patient with Peutz-Jeghers syndrome with early-onset gastric cancer.
Takahashi M; Sakayori M; Takahashi S; Kato T; Kaji M; Kawahara M; Suzuki T; Kato S; Kato S; Shibata H; Murakawa Y; Yoshioka T; Ishioka C
J Gastroenterol; 2004 Dec; 39(12):1210-4. PubMed ID: 15622488
[TBL] [Abstract][Full Text] [Related]
20. Frequency and spectrum of cancers in the Peutz-Jeghers syndrome.
Hearle N; Schumacher V; Menko FH; Olschwang S; Boardman LA; Gille JJ; Keller JJ; Westerman AM; Scott RJ; Lim W; Trimbath JD; Giardiello FM; Gruber SB; Offerhaus GJ; de Rooij FW; Wilson JH; Hansmann A; Möslein G; Royer-Pokora B; Vogel T; Phillips RK; Spigelman AD; Houlston RS
Clin Cancer Res; 2006 May; 12(10):3209-15. PubMed ID: 16707622
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]