BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 12095312)

  • 1. Evidence of CFTR function in cystic fibrosis after systemic administration of 4-phenylbutyrate.
    Zeitlin PL; Diener-West M; Rubenstein RC; Boyle MP; Lee CK; Brass-Ernst L
    Mol Ther; 2002 Jul; 6(1):119-26. PubMed ID: 12095312
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A pilot clinical trial of oral sodium 4-phenylbutyrate (Buphenyl) in deltaF508-homozygous cystic fibrosis patients: partial restoration of nasal epithelial CFTR function.
    Rubenstein RC; Zeitlin PL
    Am J Respir Crit Care Med; 1998 Feb; 157(2):484-90. PubMed ID: 9476862
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Modulation of deltaF508 cystic fibrosis transmembrane regulator trafficking and function with 4-phenylbutyrate and flavonoids.
    Lim M; McKenzie K; Floyd AD; Kwon E; Zeitlin PL
    Am J Respir Cell Mol Biol; 2004 Sep; 31(3):351-7. PubMed ID: 15191910
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In vitro pharmacologic restoration of CFTR-mediated chloride transport with sodium 4-phenylbutyrate in cystic fibrosis epithelial cells containing delta F508-CFTR.
    Rubenstein RC; Egan ME; Zeitlin PL
    J Clin Invest; 1997 Nov; 100(10):2457-65. PubMed ID: 9366560
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Gentamicin-induced correction of CFTR function in patients with cystic fibrosis and CFTR stop mutations.
    Wilschanski M; Yahav Y; Yaacov Y; Blau H; Bentur L; Rivlin J; Aviram M; Bdolah-Abram T; Bebok Z; Shushi L; Kerem B; Kerem E
    N Engl J Med; 2003 Oct; 349(15):1433-41. PubMed ID: 14534336
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of deltaF508 CFTR in a cystic fibrosis respiratory epithelial cell line by 4-phenylbutyrate, genistein and CPX.
    Andersson C; Roomans GM
    Eur Respir J; 2000 May; 15(5):937-41. PubMed ID: 10853862
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sildenafil (Viagra) corrects DeltaF508-CFTR location in nasal epithelial cells from patients with cystic fibrosis.
    Dormer RL; Harris CM; Clark Z; Pereira MM; Doull IJ; Norez C; Becq F; McPherson MA
    Thorax; 2005 Jan; 60(1):55-9. PubMed ID: 15618584
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pharmacological treatment of the ion transport defect in cystic fibrosis.
    Roomans GM
    Expert Opin Investig Drugs; 2001 Jan; 10(1):1-19. PubMed ID: 11116277
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The CF-CIRC study: a French collaborative study to assess the accuracy of cystic fibrosis diagnosis in neonatal screening.
    Sermet-Gaudelus I; Roussel D; Bui S; Deneuville E; Huet F; Reix P; Bellon G; Lenoir G; Edelman A
    BMC Pediatr; 2006 Oct; 6():25. PubMed ID: 17018149
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Curcumin does not stimulate cAMP-mediated chloride transport in cystic fibrosis airway epithelial cells.
    Dragomir A; Björstad J; Hjelte L; Roomans GM
    Biochem Biophys Res Commun; 2004 Sep; 322(2):447-51. PubMed ID: 15325250
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A double-blind, placebo controlled, dose ranging study to evaluate the safety and biological efficacy of the lipid-DNA complex GR213487B in the nasal epithelium of adult patients with cystic fibrosis.
    Knowles MR; Noone PG; Hohneker K; Johnson LG; Boucher RC; Efthimiou J; Crawford C; Brown R; Schwartzbach C; Pearlman R
    Hum Gene Ther; 1998 Jan; 9(2):249-69. PubMed ID: 9472784
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Proinflammatory effect of sodium 4-phenylbutyrate in deltaF508-cystic fibrosis transmembrane conductance regulator lung epithelial cells: involvement of extracellular signal-regulated protein kinase 1/2 and c-Jun-NH2-terminal kinase signaling.
    Roque T; Boncoeur E; Saint-Criq V; Bonvin E; Clement A; Tabary O; Jacquot J
    J Pharmacol Exp Ther; 2008 Sep; 326(3):949-56. PubMed ID: 18574003
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effectiveness of PTC124 treatment of cystic fibrosis caused by nonsense mutations: a prospective phase II trial.
    Kerem E; Hirawat S; Armoni S; Yaakov Y; Shoseyov D; Cohen M; Nissim-Rafinia M; Blau H; Rivlin J; Aviram M; Elfring GL; Northcutt VJ; Miller LL; Kerem B; Wilschanski M
    Lancet; 2008 Aug; 372(9640):719-27. PubMed ID: 18722008
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression of delta F508 cystic fibrosis transmembrane conductance regulator protein and related chloride transport properties in the gallbladder epithelium from cystic fibrosis patients.
    Dray-Charier N; Paul A; Scoazec JY; Veissière D; Mergey M; Capeau J; Soubrane O; Housset C
    Hepatology; 1999 Jun; 29(6):1624-34. PubMed ID: 10347100
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ataluren (PTC124) induces cystic fibrosis transmembrane conductance regulator protein expression and activity in children with nonsense mutation cystic fibrosis.
    Sermet-Gaudelus I; Boeck KD; Casimir GJ; Vermeulen F; Leal T; Mogenet A; Roussel D; Fritsch J; Hanssens L; Hirawat S; Miller NL; Constantine S; Reha A; Ajayi T; Elfring GL; Miller LL
    Am J Respir Crit Care Med; 2010 Nov; 182(10):1262-72. PubMed ID: 20622033
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of cystic fibrosis transmembrane conductance regulator by microRNA-145, -223, and -494 is altered in ΔF508 cystic fibrosis airway epithelium.
    Oglesby IK; Chotirmall SH; McElvaney NG; Greene CM
    J Immunol; 2013 Apr; 190(7):3354-62. PubMed ID: 23436935
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A placebo-controlled study of liposome-mediated gene transfer to the nasal epithelium of patients with cystic fibrosis.
    Gill DR; Southern KW; Mofford KA; Seddon T; Huang L; Sorgi F; Thomson A; MacVinish LJ; Ratcliff R; Bilton D; Lane DJ; Littlewood JM; Webb AK; Middleton PG; Colledge WH; Cuthbert AW; Evans MJ; Higgins CF; Hyde SC
    Gene Ther; 1997 Mar; 4(3):199-209. PubMed ID: 9135733
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effect of macrolides on in vivo ion transport across cystic fibrosis nasal epithelium.
    Barker PM; Gillie DJ; Schechter MS; Rubin BK
    Am J Respir Crit Care Med; 2005 Apr; 171(8):868-71. PubMed ID: 15657462
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Gene expression profile analysis of 4-phenylbutyrate treatment of IB3-1 bronchial epithelial cell line demonstrates a major influence on heat-shock proteins.
    Wright JM; Zeitlin PL; Cebotaru L; Guggino SE; Guggino WB
    Physiol Genomics; 2004 Jan; 16(2):204-11. PubMed ID: 14583596
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Assessment of the efficacy of in vivo CFTR protein replacement therapy in CF mice.
    Ramjeesingh M; Huan LJ; Wilschanski M; Durie P; Li C; Gyomorey K; Wang Y; Kent G; Tanswell KA; Cutz E; Ackerley C; Bear CE
    Hum Gene Ther; 1998 Mar; 9(4):521-8. PubMed ID: 9525313
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.