172 related articles for article (PubMed ID: 12099378)
1. Mechanisms involved in the establishment of tolerance through costimulatory blockade and BMT: lack of requirement for CD40L-mediated signaling for tolerance or deletion of donor-reactive CD4+ cells.
Kurtz J; Ito H; Wekerle T; Shaffer J; Sykes M
Am J Transplant; 2001 Nov; 1(4):339-49. PubMed ID: 12099378
[TBL] [Abstract][Full Text] [Related]
2. CD4 T cell-mediated alloresistance to fully MHC-mismatched allogeneic bone marrow engraftment is dependent on CD40-CD40 ligand interactions, and lasting T cell tolerance is induced by bone marrow transplantation with initial blockade of this pathway.
Ito H; Kurtz J; Shaffer J; Sykes M
J Immunol; 2001 Mar; 166(5):2970-81. PubMed ID: 11207246
[TBL] [Abstract][Full Text] [Related]
3. Extrathymic T cell deletion and allogeneic stem cell engraftment induced with costimulatory blockade is followed by central T cell tolerance.
Wekerle T; Sayegh MH; Hill J; Zhao Y; Chandraker A; Swenson KG; Zhao G; Sykes M
J Exp Med; 1998 Jun; 187(12):2037-44. PubMed ID: 9625763
[TBL] [Abstract][Full Text] [Related]
4. The role of non-deletional tolerance mechanisms in a murine model of mixed chimerism with costimulation blockade.
Bigenzahn S; Blaha P; Koporc Z; Pree I; Selzer E; Bergmeister H; Wrba F; Heusser C; Wagner K; Muehlbacher F; Wekerle T
Am J Transplant; 2005 Jun; 5(6):1237-47. PubMed ID: 15888027
[TBL] [Abstract][Full Text] [Related]
5. Lack of role for CsA-sensitive or Fas pathways in the tolerization of CD4 T cells via BMT and anti-CD40L.
Kurtz J; Lie A; Griffith M; Eysaman S; Shaffer J; Anosova N; Turka L; Benichou G; Sykes M
Am J Transplant; 2003 Jul; 3(7):804-16. PubMed ID: 12814472
[TBL] [Abstract][Full Text] [Related]
6. Additional monoclonal antibody (mAB) injections can replace thymic irradiation to allow induction of mixed chimerism and tolerance in mice receiving bone marrow transplantation after conditioning with anti-T cell mABs and 3-Gy whole body irradiation.
Tomita Y; Sachs DH; Khan A; Sykes M
Transplantation; 1996 Feb; 61(3):469-77. PubMed ID: 8610363
[TBL] [Abstract][Full Text] [Related]
7. Flt3-L augments the engraftment of donor-derived bone marrow cells when combined with sublethal irradiation and costimulatory (CD28/B7 and CD40/CD40L) blockade.
Woodward JE; Salam A; Logar AJ; Schaefer AT; Rao AS
Cell Transplant; 2002; 11(2):147-59. PubMed ID: 12099638
[TBL] [Abstract][Full Text] [Related]
8. Mechanisms of early peripheral CD4 T-cell tolerance induction by anti-CD154 monoclonal antibody and allogeneic bone marrow transplantation: evidence for anergy and deletion but not regulatory cells.
Kurtz J; Shaffer J; Lie A; Anosova N; Benichou G; Sykes M
Blood; 2004 Jun; 103(11):4336-43. PubMed ID: 14962909
[TBL] [Abstract][Full Text] [Related]
9. Anti-CD40L monoclonal antibodies can replace anti-CD4 monoclonal antibodies for the nonmyeloablative induction of mixed xenogeneic chimerism.
Ito H; Takeuchi Y; Shaffer J; Sykes M
Transplantation; 2006 Jul; 82(2):251-7. PubMed ID: 16858289
[TBL] [Abstract][Full Text] [Related]
10. Early regulation of CD8 T cell alloreactivity by CD4+CD25- T cells in recipients of anti-CD154 antibody and allogeneic BMT is followed by rapid peripheral deletion of donor-reactive CD8+ T cells, precluding a role for sustained regulation.
Fehr T; Takeuchi Y; Kurtz J; Wekerle T; Sykes M
Eur J Immunol; 2005 Sep; 35(9):2679-90. PubMed ID: 16082727
[TBL] [Abstract][Full Text] [Related]
11. LAG-3, TGF-β, and cell-intrinsic PD-1 inhibitory pathways contribute to CD8 but not CD4 T-cell tolerance induced by allogeneic BMT with anti-CD40L.
Lucas CL; Workman CJ; Beyaz S; LoCascio S; Zhao G; Vignali DA; Sykes M
Blood; 2011 May; 117(20):5532-40. PubMed ID: 21422469
[TBL] [Abstract][Full Text] [Related]
12. Host CD40 ligand deficiency induces long-term allograft survival and donor-specific tolerance in mouse cardiac transplantation but does not prevent graft arteriosclerosis.
Shimizu K; Schönbeck U; Mach F; Libby P; Mitchell RN
J Immunol; 2000 Sep; 165(6):3506-18. PubMed ID: 10975872
[TBL] [Abstract][Full Text] [Related]
13. Tolerance induction through megadose bone marrow transplantation with two-signal blockade.
Lee EN; Lee J; Kim EY; Park HJ; Chang CY; Jung DY; Choi SY; Lee SK; Kwon CH; Joh JW; Kim SJ
J Surg Res; 2006 Jan; 130(1):102-9. PubMed ID: 16183077
[TBL] [Abstract][Full Text] [Related]
14. Blockade of CD40 ligand-CD40 interaction impairs CD4+ T cell-mediated alloreactivity by inhibiting mature donor T cell expansion and function after bone marrow transplantation.
Blazar BR; Taylor PA; Panoskaltsis-Mortari A; Buhlman J; Xu J; Flavell RA; Korngold R; Noelle R; Vallera DA
J Immunol; 1997 Jan; 158(1):29-39. PubMed ID: 8977172
[TBL] [Abstract][Full Text] [Related]
15. CD40 ligand blockade induces CD4+ T cell tolerance and linked suppression.
Honey K; Cobbold SP; Waldmann H
J Immunol; 1999 Nov; 163(9):4805-10. PubMed ID: 10528180
[TBL] [Abstract][Full Text] [Related]
16. Anti-CD154 or CTLA4Ig obviates the need for thymic irradiation in a non-myeloablative conditioning regimen for the induction of mixed hematopoietic chimerism and tolerance.
Wekerle T; Sayegh MH; Ito H; Hill J; Chandraker A; Pearson DA; Swenson KG; Zhao G; Sykes M
Transplantation; 1999 Nov; 68(9):1348-55. PubMed ID: 10573075
[TBL] [Abstract][Full Text] [Related]
17. CTLA-4 on alloreactive CD4 T cells interacts with recipient CD80/86 to promote tolerance.
Kurtz J; Raval F; Vallot C; Der J; Sykes M
Blood; 2009 Apr; 113(15):3475-84. PubMed ID: 19179471
[TBL] [Abstract][Full Text] [Related]
18. Earlier low-dose TBI or DST overcomes CD8+ T-cell-mediated alloresistance to allogeneic marrow in recipients of anti-CD40L.
Takeuchi Y; Ito H; Kurtz J; Wekerle T; Ho L; Sykes M
Am J Transplant; 2004 Jan; 4(1):31-40. PubMed ID: 14678032
[TBL] [Abstract][Full Text] [Related]
19. Combined effects of calcineurin inhibitors or sirolimus with anti-CD40L mAb on alloengraftment under nonmyeloablative conditions.
Taylor PA; Lees CJ; Wilson JM; Ehrhardt MJ; Campbell MT; Noelle RJ; Blazar BR
Blood; 2002 Nov; 100(9):3400-7. PubMed ID: 12384443
[TBL] [Abstract][Full Text] [Related]
20. Aggressive skin allograft rejection in CD28-/- mice independent of the CD40/CD40L costimulatory pathway.
Ha J; Bingaman AW; Durham MM; Pearson TC; Larsen CP
Transpl Immunol; 2001 Oct; 9(1):13-7. PubMed ID: 11680567
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]