BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

479 related articles for article (PubMed ID: 12101225)

  • 1. PIN1 is an E2F target gene essential for Neu/Ras-induced transformation of mammary epithelial cells.
    Ryo A; Liou YC; Wulf G; Nakamura M; Lee SW; Lu KP
    Mol Cell Biol; 2002 Aug; 22(15):5281-95. PubMed ID: 12101225
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1.
    Wulf GM; Ryo A; Wulf GG; Lee SW; Niu T; Petkova V; Lu KP
    EMBO J; 2001 Jul; 20(13):3459-72. PubMed ID: 11432833
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Modeling breast cancer in vivo and ex vivo reveals an essential role of Pin1 in tumorigenesis.
    Wulf G; Garg P; Liou YC; Iglehart D; Lu KP
    EMBO J; 2004 Aug; 23(16):3397-407. PubMed ID: 15257284
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes.
    Liou YC; Ryo A; Huang HK; Lu PJ; Bronson R; Fujimori F; Uchida T; Hunter T; Lu KP
    Proc Natl Acad Sci U S A; 2002 Feb; 99(3):1335-40. PubMed ID: 11805292
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The prolyl isomerase Pin1 in breast development and cancer.
    Wulf G; Ryo A; Liou YC; Lu KP
    Breast Cancer Res; 2003; 5(2):76-82. PubMed ID: 12631385
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway.
    Lee RJ; Albanese C; Fu M; D'Amico M; Lin B; Watanabe G; Haines GK; Siegel PM; Hung MC; Yarden Y; Horowitz JM; Muller WJ; Pestell RG
    Mol Cell Biol; 2000 Jan; 20(2):672-83. PubMed ID: 10611246
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Prolyl isomerase Pin1: a catalyst for oncogenesis and a potential therapeutic target in cancer.
    Ryo A; Liou YC; Lu KP; Wulf G
    J Cell Sci; 2003 Mar; 116(Pt 5):773-83. PubMed ID: 12571275
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Prolyl isomerase Pin1 is highly expressed in Her2-positive breast cancer and regulates erbB2 protein stability.
    Lam PB; Burga LN; Wu BP; Hofstatter EW; Lu KP; Wulf GM
    Mol Cancer; 2008 Dec; 7():91. PubMed ID: 19077306
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Prevalent overexpression of prolyl isomerase Pin1 in human cancers.
    Bao L; Kimzey A; Sauter G; Sowadski JM; Lu KP; Wang DG
    Am J Pathol; 2004 May; 164(5):1727-37. PubMed ID: 15111319
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pin1 regulates centrosome duplication, and its overexpression induces centrosome amplification, chromosome instability, and oncogenesis.
    Suizu F; Ryo A; Wulf G; Lim J; Lu KP
    Mol Cell Biol; 2006 Feb; 26(4):1463-79. PubMed ID: 16449657
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The prolyl isomerase Pin1 enhances HER-2 expression and cellular transformation via its interaction with mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1.
    Khanal P; Namgoong GM; Kang BS; Woo ER; Choi HS
    Mol Cancer Ther; 2010 Mar; 9(3):606-16. PubMed ID: 20179161
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pin1 is overexpressed in oral squamous cell carcinoma and its levels correlate with cyclin D1 overexpression.
    Miyashita H; Mori S; Motegi K; Fukumoto M; Uchida T
    Oncol Rep; 2003; 10(2):455-61. PubMed ID: 12579289
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting carcinogenesis: a role for the prolyl isomerase Pin1?
    Lu KP; Suizu F; Zhou XZ; Finn G; Lam P; Wulf G
    Mol Carcinog; 2006 Jun; 45(6):397-402. PubMed ID: 16652378
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins.
    Zhou XZ; Kops O; Werner A; Lu PJ; Shen M; Stoller G; Küllertz G; Stark M; Fischer G; Lu KP
    Mol Cell; 2000 Oct; 6(4):873-83. PubMed ID: 11090625
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ErbB2/Neu-induced, cyclin D1-dependent transformation is accelerated in p27-haploinsufficient mammary epithelial cells but impaired in p27-null cells.
    Muraoka RS; Lenferink AE; Law B; Hamilton E; Brantley DM; Roebuck LR; Arteaga CL
    Mol Cell Biol; 2002 Apr; 22(7):2204-19. PubMed ID: 11884607
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Expression status of Pin1 and cyclins in oral squamous cell carcinoma: Pin1 correlates with Cyclin D1 mRNA expression and clinical significance of cyclins.
    Miyashita H; Uchida T; Mori S; Echigo S; Motegi K
    Oncol Rep; 2003; 10(4):1045-8. PubMed ID: 12792768
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC.
    Ryo A; Nakamura M; Wulf G; Liou YC; Lu KP
    Nat Cell Biol; 2001 Sep; 3(9):793-801. PubMed ID: 11533658
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The prolyl isomerase Pin1 interacts with a ribosomal protein S6 kinase to enhance insulin-induced AP-1 activity and cellular transformation.
    Lee NY; Choi HK; Shim JH; Kang KW; Dong Z; Choi HS
    Carcinogenesis; 2009 Apr; 30(4):671-81. PubMed ID: 19168580
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Construction of a cyclin D1-Cdk2 fusion protein to model the biological functions of cyclin D1-Cdk2 complexes.
    Chytil A; Waltner-Law M; West R; Friedman D; Aakre M; Barker D; Law B
    J Biol Chem; 2004 Nov; 279(46):47688-98. PubMed ID: 15355984
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Understanding the role of PIN1 in hepatocellular carcinoma.
    Cheng CW; Leong KW; Tse E
    World J Gastroenterol; 2016 Dec; 22(45):9921-9932. PubMed ID: 28018099
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.