231 related articles for article (PubMed ID: 12102621)
1. The structure of apo and holo forms of xylose reductase, a dimeric aldo-keto reductase from Candida tenuis.
Kavanagh KL; Klimacek M; Nidetzky B; Wilson DK
Biochemistry; 2002 Jul; 41(28):8785-95. PubMed ID: 12102621
[TBL] [Abstract][Full Text] [Related]
2. The xylose reductase (AKR2B5) structure: homology and divergence from other aldo-keto reductases and opportunities for protein engineering.
Wilson DK; Kavanagh KL; Klimacek M; Nidetzky B
Chem Biol Interact; 2003 Feb; 143-144():515-21. PubMed ID: 12604237
[TBL] [Abstract][Full Text] [Related]
3. Transient-state and steady-state kinetic studies of the mechanism of NADH-dependent aldehyde reduction catalyzed by xylose reductase from the yeast Candida tenuis.
Nidetzky B; Klimacek M; Mayr P
Biochemistry; 2001 Aug; 40(34):10371-81. PubMed ID: 11513616
[TBL] [Abstract][Full Text] [Related]
4. Probing the substrate binding site of Candida tenuis xylose reductase (AKR2B5) with site-directed mutagenesis.
Kratzer R; Leitgeb S; Wilson DK; Nidetzky B
Biochem J; 2006 Jan; 393(Pt 1):51-8. PubMed ID: 16336198
[TBL] [Abstract][Full Text] [Related]
5. Structure of xylose reductase bound to NAD+ and the basis for single and dual co-substrate specificity in family 2 aldo-keto reductases.
Kavanagh KL; Klimacek M; Nidetzky B; Wilson DK
Biochem J; 2003 Jul; 373(Pt 2):319-26. PubMed ID: 12733986
[TBL] [Abstract][Full Text] [Related]
6. Catalytic mechanism and substrate selectivity of aldo-keto reductases: insights from structure-function studies of Candida tenuis xylose reductase.
Kratzer R; Wilson DK; Nidetzky B
IUBMB Life; 2006 Sep; 58(9):499-507. PubMed ID: 17002977
[TBL] [Abstract][Full Text] [Related]
7. Electrostatic stabilization in a pre-organized polar active site: the catalytic role of Lys-80 in Candida tenuis xylose reductase (AKR2B5) probed by site-directed mutagenesis and functional complementation studies.
Kratzer R; Nidetzky B
Biochem J; 2005 Jul; 389(Pt 2):507-15. PubMed ID: 15799715
[TBL] [Abstract][Full Text] [Related]
8. Structural and functional properties of aldose xylose reductase from the D-xylose-metabolizing yeast Candida tenuis.
Nidetzky B; Mayr P; Neuhauser W; Puchberger M
Chem Biol Interact; 2001 Jan; 130-132(1-3):583-95. PubMed ID: 11306077
[TBL] [Abstract][Full Text] [Related]
9. Catalytic reaction profile for NADH-dependent reduction of aromatic aldehydes by xylose reductase from Candida tenuis.
Mayr P; Nidetzky B
Biochem J; 2002 Sep; 366(Pt 3):889-99. PubMed ID: 12003638
[TBL] [Abstract][Full Text] [Related]
10. Studies of the enzymic mechanism of Candida tenuis xylose reductase (AKR 2B5): X-ray structure and catalytic reaction profile for the H113A mutant.
Kratzer R; Kavanagh KL; Wilson DK; Nidetzky B
Biochemistry; 2004 May; 43(17):4944-54. PubMed ID: 15109252
[TBL] [Abstract][Full Text] [Related]
11. Fine tuning of coenzyme specificity in family 2 aldo-keto reductases revealed by crystal structures of the Lys-274-->Arg mutant of Candida tenuis xylose reductase (AKR2B5) bound to NAD+ and NADP+.
Leitgeb S; Petschacher B; Wilson DK; Nidetzky B
FEBS Lett; 2005 Jan; 579(3):763-7. PubMed ID: 15670843
[TBL] [Abstract][Full Text] [Related]
12. Insights from modeling the 3D structure of NAD(P)H-dependent D-xylose reductase of Pichia stipitis and its binding interactions with NAD and NADP.
Wang JF; Wei DQ; Lin Y; Wang YH; Du HL; Li YX; Chou KC
Biochem Biophys Res Commun; 2007 Jul; 359(2):323-9. PubMed ID: 17544374
[TBL] [Abstract][Full Text] [Related]
13. Acceleration of an aldo-keto reductase by minimal loop engineering.
Krump C; Vogl M; Brecker L; Nidetzky B; Kratzer R
Protein Eng Des Sel; 2014 Jul; 27(7):245-8. PubMed ID: 24951537
[TBL] [Abstract][Full Text] [Related]
14. Exploring the active site of yeast xylose reductase by site-directed mutagenesis of sequence motifs characteristic of two dehydrogenase/reductase family types.
Klimacek M; Szekely M; Griessler R; Nidetzky B
FEBS Lett; 2001 Jul; 500(3):149-52. PubMed ID: 11445075
[TBL] [Abstract][Full Text] [Related]
15. The coenzyme specificity of Candida tenuis xylose reductase (AKR2B5) explored by site-directed mutagenesis and X-ray crystallography.
Petschacher B; Leitgeb S; Kavanagh KL; Wilson DK; Nidetzky B
Biochem J; 2005 Jan; 385(Pt 1):75-83. PubMed ID: 15320875
[TBL] [Abstract][Full Text] [Related]
16. The catalytic mechanism of NADH-dependent reduction of 9,10-phenanthrenequinone by Candida tenuis xylose reductase reveals plasticity in an aldo-keto reductase active site.
Pival SL; Klimacek M; Nidetzky B
Biochem J; 2009 Jun; 421(1):43-9. PubMed ID: 19368528
[TBL] [Abstract][Full Text] [Related]
17. Crystal structure of yeast xylose reductase in complex with a novel NADP-DTT adduct provides insights into substrate recognition and catalysis.
Paidimuddala B; Mohapatra SB; Gummadi SN; Manoj N
FEBS J; 2018 Dec; 285(23):4445-4464. PubMed ID: 30269423
[TBL] [Abstract][Full Text] [Related]
18. Altering dimer contacts in xylose reductase from Candida tenuis by site-directed mutagenesis: structural and functional properties of R180A mutant.
Klimacek M; Wührer F; Kavanagh KL; Wilson DK; Nidetzky B
Chem Biol Interact; 2003 Feb; 143-144():523-32. PubMed ID: 12604238
[TBL] [Abstract][Full Text] [Related]
19. Comparative anatomy of the aldo-keto reductase superfamily.
Jez JM; Bennett MJ; Schlegel BP; Lewis M; Penning TM
Biochem J; 1997 Sep; 326 ( Pt 3)(Pt 3):625-36. PubMed ID: 9307009
[TBL] [Abstract][Full Text] [Related]
20. Identification of Candida tenuis xylose reductase as highly selective biocatalyst for the synthesis of aromatic alpha-hydroxy esters and improvement of its efficiency by protein engineering.
Kratzer R; Nidetzky B
Chem Commun (Camb); 2007 Mar; (10):1047-9. PubMed ID: 17325801
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
