These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

397 related articles for article (PubMed ID: 12110584)

  • 1. Tyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulation.
    Goldberg Z; Vogt Sionov R; Berger M; Zwang Y; Perets R; Van Etten RA; Oren M; Taya Y; Haupt Y
    EMBO J; 2002 Jul; 21(14):3715-27. PubMed ID: 12110584
    [TBL] [Abstract][Full Text] [Related]  

  • 2. c-Abl phosphorylates Hdm2 at tyrosine 276 in response to DNA damage and regulates interaction with ARF.
    Dias SS; Milne DM; Meek DW
    Oncogene; 2006 Oct; 25(50):6666-71. PubMed ID: 16702947
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage.
    Maya R; Balass M; Kim ST; Shkedy D; Leal JF; Shifman O; Moas M; Buschmann T; Ronai Z; Shiloh Y; Kastan MB; Katzir E; Oren M
    Genes Dev; 2001 May; 15(9):1067-77. PubMed ID: 11331603
    [TBL] [Abstract][Full Text] [Related]  

  • 4. C-Abl as a modulator of p53.
    Levav-Cohen Y; Goldberg Z; Zuckerman V; Grossman T; Haupt S; Haupt Y
    Biochem Biophys Res Commun; 2005 Jun; 331(3):737-49. PubMed ID: 15865930
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage.
    Chen L; Gilkes DM; Pan Y; Lane WS; Chen J
    EMBO J; 2005 Oct; 24(19):3411-22. PubMed ID: 16163388
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphorylation of the Mdm2 oncoprotein by the c-Abl tyrosine kinase regulates p53 tumor suppression and the radiosensitivity of mice.
    Carr MI; Roderick JE; Zhang H; Woda BA; Kelliher MA; Jones SN
    Proc Natl Acad Sci U S A; 2016 Dec; 113(52):15024-15029. PubMed ID: 27956626
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage.
    Pereg Y; Shkedy D; de Graaf P; Meulmeester E; Edelson-Averbukh M; Salek M; Biton S; Teunisse AF; Lehmann WD; Jochemsen AG; Shiloh Y
    Proc Natl Acad Sci U S A; 2005 Apr; 102(14):5056-61. PubMed ID: 15788536
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage.
    Khosravi R; Maya R; Gottlieb T; Oren M; Shiloh Y; Shkedy D
    Proc Natl Acad Sci U S A; 1999 Dec; 96(26):14973-7. PubMed ID: 10611322
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ATM complexes with HDM2 and promotes its rapid phosphorylation in a p53-independent manner in normal and tumor human cells exposed to ionizing radiation.
    de Toledo SM; Azzam EI; Dahlberg WK; Gooding TB; Little JB
    Oncogene; 2000 Dec; 19(54):6185-93. PubMed ID: 11175332
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Stabilization of p53 by CP-31398 inhibits ubiquitination without altering phosphorylation at serine 15 or 20 or MDM2 binding.
    Wang W; Takimoto R; Rastinejad F; El-Deiry WS
    Mol Cell Biol; 2003 Mar; 23(6):2171-81. PubMed ID: 12612087
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Awakening angels.
    Lane D
    Nature; 1998 Aug; 394(6694):616-7. PubMed ID: 9716124
    [No Abstract]   [Full Text] [Related]  

  • 12. c-Abl phosphorylates Hdmx and regulates its interaction with p53.
    Zuckerman V; Lenos K; Popowicz GM; Silberman I; Grossman T; Marine JC; Holak TA; Jochemsen AG; Haupt Y
    J Biol Chem; 2009 Feb; 284(6):4031-9. PubMed ID: 19075013
    [TBL] [Abstract][Full Text] [Related]  

  • 13. c-Abl neutralizes the inhibitory effect of Mdm2 on p53.
    Sionov RV; Moallem E; Berger M; Kazaz A; Gerlitz O; Ben-Neriah Y; Oren M; Haupt Y
    J Biol Chem; 1999 Mar; 274(13):8371-4. PubMed ID: 10085066
    [TBL] [Abstract][Full Text] [Related]  

  • 14. HMG-CoA reductase inhibitors, statins, induce phosphorylation of Mdm2 and attenuate the p53 response to DNA damage.
    Pääjärvi G; Roudier E; Crisby M; Högberg J; Stenius U
    FASEB J; 2005 Mar; 19(3):476-8. PubMed ID: 15625077
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PML regulates p53 stability by sequestering Mdm2 to the nucleolus.
    Bernardi R; Scaglioni PP; Bergmann S; Horn HF; Vousden KH; Pandolfi PP
    Nat Cell Biol; 2004 Jul; 6(7):665-72. PubMed ID: 15195100
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Critical roles for the serine 20, but not the serine 15, phosphorylation site and for the polyproline domain in regulating p53 turnover.
    Dumaz N; Milne DM; Jardine LJ; Meek DW
    Biochem J; 2001 Oct; 359(Pt 2):459-64. PubMed ID: 11583595
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Functional role of Mdm2 phosphorylation by ATR in attenuation of p53 nuclear export.
    Shinozaki T; Nota A; Taya Y; Okamoto K
    Oncogene; 2003 Dec; 22(55):8870-80. PubMed ID: 14654783
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2.
    Shieh SY; Ikeda M; Taya Y; Prives C
    Cell; 1997 Oct; 91(3):325-34. PubMed ID: 9363941
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Determination of cell fate by c-Abl activation in the response to DNA damage.
    Kharbanda S; Yuan ZM; Weichselbaum R; Kufe D
    Oncogene; 1998 Dec; 17(25):3309-18. PubMed ID: 9916993
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The promyelocytic leukemia protein protects p53 from Mdm2-mediated inhibition and degradation.
    Louria-Hayon I; Grossman T; Sionov RV; Alsheich O; Pandolfi PP; Haupt Y
    J Biol Chem; 2003 Aug; 278(35):33134-41. PubMed ID: 12810724
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.