176 related articles for article (PubMed ID: 12113810)
1. Synthesis and anti-influenza virus activity of 7-O-alkylated derivatives related to zanamivir.
Honda T; Masuda T; Yoshida S; Arai M; Kaneko S; Yamashita M
Bioorg Med Chem Lett; 2002 Aug; 12(15):1925-8. PubMed ID: 12113810
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and anti-influenza evaluation of polyvalent sialidase inhibitors bearing 4-guanidino-Neu5Ac2en derivatives.
Honda T; Yoshida S; Arai M; Masuda T; Yamashita M
Bioorg Med Chem Lett; 2002 Aug; 12(15):1929-32. PubMed ID: 12113811
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and anti-influenza evaluation of orally active bicyclic ether derivatives related to zanamivir.
Masuda T; Shibuya S; Arai M; Yoshida S; Tomozawa T; Ohno A; Yamashita M; Honda T
Bioorg Med Chem Lett; 2003 Feb; 13(4):669-73. PubMed ID: 12639555
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and anti-influenza virus activity of 4-guanidino-7-substituted Neu5Ac2en derivatives.
Honda T; Masuda T; Yoshida S; Arai M; Kobayashi Y; Yamashita M
Bioorg Med Chem Lett; 2002 Aug; 12(15):1921-4. PubMed ID: 12113809
[TBL] [Abstract][Full Text] [Related]
5. Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 1. Discovery, synthesis, biological activity, and structure-activity relationships of 4-guanidino- and 4-amino-4H-pyran-6-carboxamides.
Smith PW; Sollis SL; Howes PD; Cherry PC; Starkey ID; Cobley KN; Weston H; Scicinski J; Merritt A; Whittington A; Wyatt P; Taylor N; Green D; Bethell R; Madar S; Fenton RJ; Morley PJ; Pateman T; Beresford A
J Med Chem; 1998 Mar; 41(6):787-97. PubMed ID: 9526555
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and influenza virus sialidase inhibitory activity of analogues of 4-Guanidino-Neu5Ac2en (Zanamivir) modified in the glycerol side-chain.
Andrews DM; Cherry PC; Humber DC; Jones PS; Keeling SP; Martin PF; Shaw CD; Swanson S
Eur J Med Chem; 1999; 34(7-8):563-74. PubMed ID: 11278042
[TBL] [Abstract][Full Text] [Related]
7. Sialidase inhibitors related to zanamivir. Further SAR studies of 4-amino-4H-pyran-2-carboxylic acid-6-propylamides.
Wyatt PG; Coomber BA; Evans DN; Jack TI; Fulton HE; Wonacott AJ; Colman P; Varghese J
Bioorg Med Chem Lett; 2001 Mar; 11(5):669-73. PubMed ID: 11266166
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and anti-influenza evaluation of polyvalent sialidase inhibitors bearing 4-guanidino-Neu5Ac2en derivatives.
Masuda T; Yoshida S; Arai M; Kaneko S; Yamashita M; Honda T
Chem Pharm Bull (Tokyo); 2003 Dec; 51(12):1386-98. PubMed ID: 14646315
[TBL] [Abstract][Full Text] [Related]
9. Highly potent and long-acting trimeric and tetrameric inhibitors of influenza virus neuraminidase.
Watson KG; Cameron R; Fenton RJ; Gower D; Hamilton S; Jin B; Krippner GY; Luttick A; McConnell D; MacDonald SJ; Mason AM; Nguyen V; Tucker SP; Wu WY
Bioorg Med Chem Lett; 2004 Mar; 14(6):1589-92. PubMed ID: 15006410
[TBL] [Abstract][Full Text] [Related]
10. Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 2. Crystallographic and molecular modeling study of complexes of 4-amino-4H-pyran-6-carboxamides and sialidase from influenza virus types A and B.
Taylor NR; Cleasby A; Singh O; Skarzynski T; Wonacott AJ; Smith PW; Sollis SL; Howes PD; Cherry PC; Bethell R; Colman P; Varghese J
J Med Chem; 1998 Mar; 41(6):798-807. PubMed ID: 9526556
[TBL] [Abstract][Full Text] [Related]
11. Zanamivir. A potent and selective inhibitor of influenza A and B viruses.
Aoki FY; Hayden FG
Clin Pharmacokinet; 1999; 36 Suppl 1():v-ix. PubMed ID: 10429834
[No Abstract] [Full Text] [Related]
12. Dimeric zanamivir conjugates with various linking groups are potent, long-lasting inhibitors of influenza neuraminidase including H5N1 avian influenza.
Macdonald SJ; Cameron R; Demaine DA; Fenton RJ; Foster G; Gower D; Hamblin JN; Hamilton S; Hart GJ; Hill AP; Inglis GG; Jin B; Jones HT; McConnell DB; McKimm-Breschkin J; Mills G; Nguyen V; Owens IJ; Parry N; Shanahan SE; Smith D; Watson KG; Wu WY; Tucker SP
J Med Chem; 2005 Apr; 48(8):2964-71. PubMed ID: 15828835
[TBL] [Abstract][Full Text] [Related]
13. Neuraminidase inhibitors as antivirals.
Colman PM
Vaccine; 2002 May; 20 Suppl 2():S55-8. PubMed ID: 12110259
[TBL] [Abstract][Full Text] [Related]
14. Synthesis of 6-acetamido-5-amino- and -5-guanidino-3, 4-dehydro-N-(2-ethylbutyryl)- 3-piperidinecarboxylic acids related to zanamivir and oseltamivir, inhibitors of influenza virus neuraminidases.
Shitara E; Nishimura Y; Nerome K; Hiramoto Y; Takeuchi T
Org Lett; 2000 Nov; 2(24):3837-40. PubMed ID: 11101432
[TBL] [Abstract][Full Text] [Related]
15. Slow-binding inhibition of sialidase from influenza virus.
Pegg MS; von Itzstein M
Biochem Mol Biol Int; 1994 Apr; 32(5):851-8. PubMed ID: 8069234
[TBL] [Abstract][Full Text] [Related]
16. 4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid is a highly effective inhibitor both of the sialidase (neuraminidase) and of growth of a wide range of influenza A and B viruses in vitro.
Woods JM; Bethell RC; Coates JA; Healy N; Hiscox SA; Pearson BA; Ryan DM; Ticehurst J; Tilling J; Walcott SM
Antimicrob Agents Chemother; 1993 Jul; 37(7):1473-9. PubMed ID: 8363379
[TBL] [Abstract][Full Text] [Related]
17. Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors.
McKimm-Breschkin JL; Sahasrabudhe A; Blick TJ; McDonald M; Colman PM; Hart GJ; Bethell RC; Varghese JN
J Virol; 1998 Mar; 72(3):2456-62. PubMed ID: 9499107
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of the growth of influenza viruses in vitro by 4-guanidino-2,4-dideoxy-N-acetylneuraminic acid.
Thomas GP; Forsyth M; Penn CR; McCauley JW
Antiviral Res; 1994 Aug; 24(4):351-6. PubMed ID: 7993078
[TBL] [Abstract][Full Text] [Related]
19. Syntheses of triazole-modified zanamivir analogues via click chemistry and anti-AIV activities.
Li J; Zheng M; Tang W; He PL; Zhu W; Li T; Zuo JP; Liu H; Jiang H
Bioorg Med Chem Lett; 2006 Oct; 16(19):5009-13. PubMed ID: 16876409
[TBL] [Abstract][Full Text] [Related]
20. Utilization of the embryonated egg for in vivo evaluation of the anti-influenza virus activity of neuraminidase inhibitors.
Sauerbrei A; Haertl A; Brandstaedt A; Schmidtke M; Wutzler P
Med Microbiol Immunol; 2006 Jun; 195(2):65-71. PubMed ID: 16059699
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]