These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

377 related articles for article (PubMed ID: 12114543)

  • 1. Internal IgH class switch region deletions are position-independent and enhanced by AID expression.
    Dudley DD; Manis JP; Zarrin AA; Kaylor L; Tian M; Alt FW
    Proc Natl Acad Sci U S A; 2002 Jul; 99(15):9984-9. PubMed ID: 12114543
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Downstream class switching leads to IgE antibody production by B lymphocytes lacking IgM switch regions.
    Zhang T; Franklin A; Boboila C; McQuay A; Gallagher MP; Manis JP; Khamlichi AA; Alt FW
    Proc Natl Acad Sci U S A; 2010 Feb; 107(7):3040-5. PubMed ID: 20133637
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evolution of the immunoglobulin heavy chain class switch recombination mechanism.
    Chaudhuri J; Basu U; Zarrin A; Yan C; Franco S; Perlot T; Vuong B; Wang J; Phan RT; Datta A; Manis J; Alt FW
    Adv Immunol; 2007; 94():157-214. PubMed ID: 17560275
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Switch recombination in a transfected plasmid occurs preferentially in a B cell line that undergoes switch recombination of its chromosomal Ig heavy chain genes.
    Stavnezer J; Bradley SP; Rousseau N; Pearson T; Shanmugam A; Waite DJ; Rogers PR; Kenter AL
    J Immunol; 1999 Aug; 163(4):2028-40. PubMed ID: 10438941
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DNA polymerase beta is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination.
    Wu X; Stavnezer J
    J Exp Med; 2007 Jul; 204(7):1677-89. PubMed ID: 17591858
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The block in immunoglobulin class switch recombination caused by activation-induced cytidine deaminase deficiency occurs prior to the generation of DNA double strand breaks in switch mu region.
    Catalan N; Selz F; Imai K; Revy P; Fischer A; Durandy A
    J Immunol; 2003 Sep; 171(5):2504-9. PubMed ID: 12928399
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Staggered AID-dependent DNA double strand breaks are the predominant DNA lesions targeted to S mu in Ig class switch recombination.
    Rush JS; Fugmann SD; Schatz DG
    Int Immunol; 2004 Apr; 16(4):549-57. PubMed ID: 15039385
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activation-induced deaminase (AID)-directed hypermutation in the immunoglobulin Smu region: implication of AID involvement in a common step of class switch recombination and somatic hypermutation.
    Nagaoka H; Muramatsu M; Yamamura N; Kinoshita K; Honjo T
    J Exp Med; 2002 Feb; 195(4):529-34. PubMed ID: 11854365
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Single-strand DNA breaks in Ig class switch recombination that depend on UNG but not AID.
    Arudchandran A; Bernstein RM; Max EE
    Int Immunol; 2008 Nov; 20(11):1381-93. PubMed ID: 18794203
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Translocation of an antibody transgene requires AID and occurs by interchromosomal switching to all switch regions except the mu switch region.
    Shansab M; Eccleston JM; Selsing E
    Eur J Immunol; 2011 May; 41(5):1456-64. PubMed ID: 21469111
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Individual substitution mutations in the AID C terminus that ablate IgH class switch recombination.
    Kadungure T; Ucher AJ; Linehan EK; Schrader CE; Stavnezer J
    PLoS One; 2015; 10(8):e0134397. PubMed ID: 26267846
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Normal isotype switching in B cells lacking the I mu exon splice donor site: evidence for multiple I mu-like germline transcripts.
    Kuzin II; Ugine GD; Wu D; Young F; Chen J; Bottaro A
    J Immunol; 2000 Feb; 164(3):1451-7. PubMed ID: 10640761
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation and targeting of recombination in extrachromosomal substrates carrying immunoglobulin switch region sequences.
    Leung H; Maizels N
    Mol Cell Biol; 1994 Feb; 14(2):1450-8. PubMed ID: 8289820
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antibody class switching mediated by yeast endonuclease-generated DNA breaks.
    Zarrin AA; Del Vecchio C; Tseng E; Gleason M; Zarin P; Tian M; Alt FW
    Science; 2007 Jan; 315(5810):377-81. PubMed ID: 17170253
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sequence dependence of chromosomal R-loops at the immunoglobulin heavy-chain Smu class switch region.
    Huang FT; Yu K; Balter BB; Selsing E; Oruc Z; Khamlichi AA; Hsieh CL; Lieber MR
    Mol Cell Biol; 2007 Aug; 27(16):5921-32. PubMed ID: 17562862
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching.
    Dong J; Panchakshari RA; Zhang T; Zhang Y; Hu J; Volpi SA; Meyers RM; Ho YJ; Du Z; Robbiani DF; Meng F; Gostissa M; Nussenzweig MC; Manis JP; Alt FW
    Nature; 2015 Sep; 525(7567):134-139. PubMed ID: 26308889
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RNA Helicase DDX1 Converts RNA G-Quadruplex Structures into R-Loops to Promote IgH Class Switch Recombination.
    Ribeiro de Almeida C; Dhir S; Dhir A; Moghaddam AE; Sattentau Q; Meinhart A; Proudfoot NJ
    Mol Cell; 2018 May; 70(4):650-662.e8. PubMed ID: 29731414
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Locus suicide recombination actively occurs on the functionally rearranged IgH allele in B-cells from inflamed human lymphoid tissues.
    Dalloul I; Boyer F; Dalloul Z; Pignarre A; Caron G; Fest T; Chatonnet F; Delaloy C; Durandy A; Jeannet R; Lereclus E; Boutouil H; Aldigier JC; Péron S; Le Noir S; Cook-Moreau J; Cogné M
    PLoS Genet; 2019 Jun; 15(6):e1007721. PubMed ID: 31199803
    [TBL] [Abstract][Full Text] [Related]  

  • 19. An evolutionarily conserved target motif for immunoglobulin class-switch recombination.
    Zarrin AA; Alt FW; Chaudhuri J; Stokes N; Kaushal D; Du Pasquier L; Tian M
    Nat Immunol; 2004 Dec; 5(12):1275-81. PubMed ID: 15531884
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70.
    Boboila C; Jankovic M; Yan CT; Wang JH; Wesemann DR; Zhang T; Fazeli A; Feldman L; Nussenzweig A; Nussenzweig M; Alt FW
    Proc Natl Acad Sci U S A; 2010 Feb; 107(7):3034-9. PubMed ID: 20133803
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.