232 related articles for article (PubMed ID: 12115055)
1. Cloning and analysis of the simocyclinone biosynthetic gene cluster of Streptomyces antibioticus Tü 6040.
Galm U; Schimana J; Fiedler HP; Schmidt J; Li SM; Heide L
Arch Microbiol; 2002 Aug; 178(2):102-14. PubMed ID: 12115055
[TBL] [Abstract][Full Text] [Related]
2. Characterization of the aminocoumarin ligase SimL from the simocyclinone pathway and tandem incubation with NovM,P,N from the novobiocin pathway.
Pacholec M; Freel Meyers CL; Oberthür M; Kahne D; Walsh CT
Biochemistry; 2005 Mar; 44(12):4949-56. PubMed ID: 15779922
[TBL] [Abstract][Full Text] [Related]
3. Identification of the coumermycin A(1) biosynthetic gene cluster of Streptomyces rishiriensis DSM 40489.
Wang ZX; Li SM; Heide L
Antimicrob Agents Chemother; 2000 Nov; 44(11):3040-8. PubMed ID: 11036020
[TBL] [Abstract][Full Text] [Related]
4. Molecular cloning and sequence analysis of the clorobiocin biosynthetic gene cluster: new insights into the biosynthesis of aminocoumarin antibiotics.
Pojer F; Li SM; Heide L
Microbiology (Reading); 2002 Dec; 148(Pt 12):3901-3911. PubMed ID: 12480894
[TBL] [Abstract][Full Text] [Related]
5. Overexpression, purification and characterization of SimL, an amide synthetase involved in simocyclinone biosynthesis.
Luft T; Li SM; Scheible H; Kammerer B; Heide L
Arch Microbiol; 2005 May; 183(4):277-85. PubMed ID: 15812631
[TBL] [Abstract][Full Text] [Related]
6. The biosynthetic gene clusters of aminocoumarin antibiotics.
Li SM; Heide L
Planta Med; 2006 Oct; 72(12):1093-9. PubMed ID: 16868863
[TBL] [Abstract][Full Text] [Related]
7. Genetic analysis of the biosynthesis of the pyrrole and carbamoyl moieties of coumermycin A1 and novobiocin.
Xu H; Wang ZX; Schmidt J; Heide L; Li SM
Mol Genet Genomics; 2002 Nov; 268(3):387-96. PubMed ID: 12436260
[TBL] [Abstract][Full Text] [Related]
8. Novobiocin biosynthesis: inactivation of the putative regulatory gene novE and heterologous expression of genes involved in aminocoumarin ring formation.
Eustáquio AS; Luft T; Wang ZX; Gust B; Chater KF; Li SM; Heide L
Arch Microbiol; 2003 Jul; 180(1):25-32. PubMed ID: 12736771
[TBL] [Abstract][Full Text] [Related]
9. Biosynthetic gene cluster of simocyclinone, a natural multihybrid antibiotic.
Trefzer A; Pelzer S; Schimana J; Stockert S; Bihlmaier C; Fiedler HP; Welzel K; Vente A; Bechthold A
Antimicrob Agents Chemother; 2002 May; 46(5):1174-82. PubMed ID: 11959542
[TBL] [Abstract][Full Text] [Related]
10. Coupling of the biosynthesis and export of the DNA gyrase inhibitor simocyclinone in Streptomyces antibioticus.
Le TB; Fiedler HP; den Hengst CD; Ahn SK; Maxwell A; Buttner MJ
Mol Microbiol; 2009 Jun; 72(6):1462-74. PubMed ID: 19460097
[TBL] [Abstract][Full Text] [Related]
11. The tallysomycin biosynthetic gene cluster from Streptoalloteichus hindustanus E465-94 ATCC 31158 unveiling new insights into the biosynthesis of the bleomycin family of antitumor antibiotics.
Tao M; Wang L; Wendt-Pienkowski E; George NP; Galm U; Zhang G; Coughlin JM; Shen B
Mol Biosyst; 2007 Jan; 3(1):60-74. PubMed ID: 17216057
[TBL] [Abstract][Full Text] [Related]
12. The neomycin biosynthetic gene cluster of Streptomyces fradiae NCIMB 8233: characterisation of an aminotransferase involved in the formation of 2-deoxystreptamine.
Huang F; Haydock SF; Mironenko T; Spiteller D; Li Y; Spencer JB
Org Biomol Chem; 2005 Apr; 3(8):1410-8. PubMed ID: 15827636
[TBL] [Abstract][Full Text] [Related]
13. Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.
Li C; Roege KE; Kelly WL
Chembiochem; 2009 Apr; 10(6):1064-72. PubMed ID: 19301315
[TBL] [Abstract][Full Text] [Related]
14. Identification of the novobiocin biosynthetic gene cluster of Streptomyces spheroides NCIB 11891.
Steffensky M; Mühlenweg A; Wang ZX; Li SM; Heide L
Antimicrob Agents Chemother; 2000 May; 44(5):1214-22. PubMed ID: 10770754
[TBL] [Abstract][Full Text] [Related]
15. Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.
Jia XY; Tian ZH; Shao L; Qu XD; Zhao QF; Tang J; Tang GL; Liu W
Chem Biol; 2006 Jun; 13(6):575-85. PubMed ID: 16793515
[TBL] [Abstract][Full Text] [Related]
16. Assembly and heterologous expression of the coumermycin A1 gene cluster and production of new derivatives by genetic engineering.
Wolpert M; Heide L; Kammerer B; Gust B
Chembiochem; 2008 Mar; 9(4):603-12. PubMed ID: 18288655
[TBL] [Abstract][Full Text] [Related]
17. S-Adenosylmethionine (SAM) and antibiotic biosynthesis: effect of external addition of SAM and of overexpression of SAM biosynthesis genes on novobiocin production in Streptomyces.
Zhao XQ; Gust B; Heide L
Arch Microbiol; 2010 Apr; 192(4):289-97. PubMed ID: 20177662
[TBL] [Abstract][Full Text] [Related]
18. novE and novG act as positive regulators of novobiocin biosynthesis.
Dangel V; Eustáquio AS; Gust B; Heide L
Arch Microbiol; 2008 Nov; 190(5):509-19. PubMed ID: 18568336
[TBL] [Abstract][Full Text] [Related]
19. Genetic organization of the biosynthetic gene cluster for the antitumor angucycline oviedomycin in Streptomyces antibioticus ATCC 11891.
Lombó F; Braña AF; Salas JA; Méndez C
Chembiochem; 2004 Sep; 5(9):1181-7. PubMed ID: 15368568
[TBL] [Abstract][Full Text] [Related]
20. SimC7 Is a Novel NAD(P)H-Dependent Ketoreductase Essential for the Antibiotic Activity of the DNA Gyrase Inhibitor Simocyclinone.
Schäfer M; Le TB; Hearnshaw SJ; Maxwell A; Challis GL; Wilkinson B; Buttner MJ
J Mol Biol; 2015 Jun; 427(12):2192-204. PubMed ID: 25861759
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]