BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

124 related articles for article (PubMed ID: 12116869)

  • 1. New 3-[4-(aryl)piperazin-1-yl]-1-(benzo[b]thiophen-2-yl)propane derivatives with dual action at 5-HT1A serotonin receptors and serotonin transporter as a new class of antidepressants.
    Orús L; Sáinz Y; Pérez S; Oficialdegui AM; Martinez J; Lasheras B; del Río J; Monge A
    Pharmazie; 2002 Jun; 57(6):355-7. PubMed ID: 12116869
    [TBL] [Abstract][Full Text] [Related]  

  • 2. New 3-[4-(3-substituted phenyl)piperazin-1-yl]-1-(benzo[b]thiophen-3-yl)propanol derivatives with dual action at 5-HT1A serotonin receptors and serotonin transporter as a new class of antidepressants.
    Orús L; Martínez J; Pérez S; Oficialdegui AM; del Castillo JC; Mourelle M; Lasheras B; del Río J; Monge A
    Pharmazie; 2002 Aug; 57(8):515-8. PubMed ID: 12227188
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New 3-[4-(aryl)piperazin-1-yl]-1-(benzo[b]thiophen-3-yl)propane derivatives with dual action at 5-HT1A serotonin receptors and serotonin transporter as a new class of antidepressants.
    Martínez J; Pérez S; Oficialdegui AM; Heras B; Orús L; Villanueva H; Palop JA; Roca J; Mourelle M; Bosch A; Del Castillo JC; Lasheras B; Tordera R; del Río J; Monge A
    Eur J Med Chem; 2001 Jan; 36(1):55-61. PubMed ID: 11231049
    [TBL] [Abstract][Full Text] [Related]  

  • 4. New 1-aryl-3-(4-arylpiperazin-1-yl)propane derivatives, with dual action at 5-HT1A serotonin receptors and serotonin transporter, as a new class of antidepressants.
    Martínez-Esparza J; Oficialdegui AM; Pérez-Silanes S; Heras B; Orús L; Palop JA; Lasheras B; Roca J; Mourelle M; Bosch A; Del Castillo JC; Tordera R; Del Río J; Monge A
    J Med Chem; 2001 Feb; 44(3):418-28. PubMed ID: 11462981
    [TBL] [Abstract][Full Text] [Related]  

  • 5. New 3-[4-(2,3-dihydro-14-benzodioxin-5-yl)piperazin-1-yl]-1-(5-substituted benzo[b]thiophen-3-yl)propanol derivatives with dual action at 5-HT(1A) serotonin receptors and serotonin transporter as a new class of antidepressants.
    Silanes SP; Orús L; Oficialdegui AM; Martínez Esparza J; Lasheras B; Del Río J; Monge A
    Pharmazie; 2004 Jul; 59(7):499-501. PubMed ID: 15296084
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Studies toward the discovery of the next generation of antidepressants. 3. Dual 5-HT1A and serotonin transporter affinity within a class of N-aryloxyethylindolylalkylamines.
    Mewshaw RE; Zhou D; Zhou P; Shi X; Hornby G; Spangler T; Scerni R; Smith D; Schechter LE; Andree TH
    J Med Chem; 2004 Jul; 47(15):3823-42. PubMed ID: 15239661
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and in vitro pharmacological evaluation of a new series of 5-HT1A 5-HT2A and 5-HT2C receptor ligands containing a norbornene nucleus.
    Fiorino F; Severino B; De Angelis F; Perissutti E; Magli E; Frecentese F; Esposito A; Massarelli P; Nencini C; Viti B; Santagada V; Caliendo G
    Pharmazie; 2009 Sep; 64(9):555-64. PubMed ID: 19827295
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Studies towards the next generation of antidepressants. Part 1: Indolylcyclohexylamines as potent serotonin reuptake inhibitors.
    Meagher KL; Mewshaw RE; Evrard DA; Zhou P; Smith DL; Scerni R; Spangler T; Abulhawa S; Shi X; Schechter LE; Andree TH
    Bioorg Med Chem Lett; 2001 Jul; 11(14):1885-8. PubMed ID: 11459653
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Substitution mode of the amide fragment in some new N-[omega-[4-(2-methoxyphenyl)piperazin-1-yl]alkyl]pyrid-2(1H)-ones and their 5-HT1A/5-HT2A activity.
    Paluchowska MH; Bugno R; Charakchieva-Minol S; Bojarski AJ; Wesołowska A
    Pol J Pharmacol; 2001; 53(4):369-76. PubMed ID: 11990083
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and biological evaluation of novel pyrrolidine-2,5-dione derivatives as potential antidepressant agents. Part 1.
    Wróbel MZ; Chodkowski A; Herold F; Gomółka A; Kleps J; Mazurek AP; Pluciński F; Mazurek A; Nowak G; Siwek A; Stachowicz K; Sławińska A; Wolak M; Szewczyk B; Satała G; Bojarski AJ; Turło J
    Eur J Med Chem; 2013 May; 63():484-500. PubMed ID: 23524160
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis and biological evaluation of new 3-[(4-aryl)piperazin-1-yl]-1-arylpropane derivatives as potential antidepressants with a dual mode of action: serotonin reuptake inhibition and 5-HT1A receptor antagonism.
    Oficialdegui AM; Martinez J; Pérez S; Heras B; Irurzun M; Palop JA; Tordera R; Lasheras B; del Río J; Monge A
    Farmaco; 2000 May; 55(5):345-53. PubMed ID: 10983279
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expression cloning of a serotonin transporter: a new way to study antidepressant drugs.
    Hoffman BJ
    Pharmacopsychiatry; 1994 Jan; 27(1):16-22. PubMed ID: 8159777
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Studies toward the discovery of the next generation of antidepressants. Part 5: 3,4-Dihydro-2H-benzo[1,4]oxazine derivatives with dual 5-HT1A receptor and serotonin transporter affinity.
    Zhou D; Harrison BL; Shah U; Andree TH; Hornby GA; Scerni R; Schechter LE; Smith DL; Sullivan KM; Mewshaw RE
    Bioorg Med Chem Lett; 2006 Mar; 16(5):1338-41. PubMed ID: 16332439
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pharmacological characterization of N,N-dimethyl-2-(2-amino-4-methylphenyl thio)benzylamine as a ligand of the serotonin transporter with high affinity and selectivity.
    Chalon S; Tarkiainen J; Garreau L; Hall H; Emond P; Vercouillie J; Farde L; Dasse P; Varnas K; Besnard JC; Halldin C; Guilloteau D
    J Pharmacol Exp Ther; 2003 Jan; 304(1):81-7. PubMed ID: 12490578
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 1,2,3,4-tetrahydroisoquinoline derivatives; lipophilicity evaluation vs. 5-HT1A receptor affinity.
    Bojarski AJ; Mokrosz MJ
    Pharmazie; 1999 Nov; 54(11):828-30. PubMed ID: 10603608
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Studies toward the discovery of the next generation of antidepressants. Part 6: Dual 5-HT1A receptor and serotonin transporter affinity within a class of arylpiperazinyl-cyclohexyl indole derivatives.
    Zhou D; Zhou P; Evrard DA; Meagher K; Webb M; Harrison BL; Huryn DM; Golembieski J; Hornby GA; Schechter LE; Smith DL; Andree TH; Mewshaw RE
    Bioorg Med Chem; 2008 Jul; 16(14):6707-23. PubMed ID: 18571421
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 3-[(Aryl)(4-fluorobenzyloxy)methyl]piperidine derivatives: high-affinity ligands for the serotonin transporter.
    Nencetti S; Demontis GC; Mazzoni MR; Betti L; Banti I; Rossello A; Lapucci A
    J Pharm Pharmacol; 2007 Oct; 59(10):1439-45. PubMed ID: 17910821
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design and synthesis of long-chain arylpiperazines with mixed affinity for serotonin transporter (SERT) and 5-HT(1A) receptor.
    Perrone R; Berardi F; Colabufo NA; Lacivita E; Larizza C; Leopoldo M; Tortorella V
    J Pharm Pharmacol; 2005 Oct; 57(10):1319-27. PubMed ID: 16259761
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interactions of antidepressants with neurotransmitter transporters and receptors and their clinical relevance.
    Richelson E
    J Clin Psychiatry; 2003; 64 Suppl 13():5-12. PubMed ID: 14552650
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novel class of arylpiperazines containing N-acylated amino acids: their synthesis, 5-HT1A, 5-HT2A receptor affinity, and in vivo pharmacological evaluation.
    Zajdel P; Subra G; Bojarski AJ; Duszyńska B; Tatarczyńska E; Nikiforuk A; Chojnacka-Wójcik E; Pawłowski M; Martinez J
    Bioorg Med Chem; 2007 Apr; 15(8):2907-19. PubMed ID: 17321139
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.