BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 12118065)

  • 1. MEK/ERK pathway mediates cell-shape-dependent plasminogen activator inhibitor type 1 gene expression upon drug-induced disruption of the microfilament and microtubule networks.
    Samarakoon R; Higgins PJ
    J Cell Sci; 2002 Aug; 115(Pt 15):3093-103. PubMed ID: 12118065
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pp60c-src mediates ERK activation/nuclear localization and PAI-1 gene expression in response to cellular deformation.
    Samarakoon R; Higgins PJ
    J Cell Physiol; 2003 Jun; 195(3):411-20. PubMed ID: 12704650
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Plasminogen activator inhibitor type-1 gene expression and induced migration in TGF-beta1-stimulated smooth muscle cells is pp60(c-src)/MEK-dependent.
    Samarakoon R; Higgins CE; Higgins SP; Kutz SM; Higgins PJ
    J Cell Physiol; 2005 Jul; 204(1):236-46. PubMed ID: 15622520
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TGF-beta1-induced plasminogen activator inhibitor-1 expression in vascular smooth muscle cells requires pp60(c-src)/EGFR(Y845) and Rho/ROCK signaling.
    Samarakoon R; Higgins SP; Higgins CE; Higgins PJ
    J Mol Cell Cardiol; 2008 Mar; 44(3):527-38. PubMed ID: 18255094
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential requirement for MEK/ERK and SMAD signaling in PAI-1 and CTGF expression in response to microtubule disruption.
    Samarakoon R; Higgins CE; Higgins SP; Higgins PJ
    Cell Signal; 2009 Jun; 21(6):986-95. PubMed ID: 19249354
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Critical role of Rho-kinase and MEK/ERK pathways for angiotensin II-induced plasminogen activator inhibitor type-1 gene expression.
    Takeda K; Ichiki T; Tokunou T; Iino N; Fujii S; Kitabatake A; Shimokawa H; Takeshita A
    Arterioscler Thromb Vasc Biol; 2001 May; 21(5):868-73. PubMed ID: 11348889
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cell shape-dependent pathway of plasminogen activator inhibitor type-1 gene expression requires cytoskeletal reorganization.
    Hawks K; Higgins PJ
    J Cell Physiol; 1998 Aug; 176(2):293-302. PubMed ID: 9648916
    [TBL] [Abstract][Full Text] [Related]  

  • 8. TGF-beta1-induced PAI-1 gene expression requires MEK activity and cell-to-substrate adhesion.
    Kutz SM; Hordines J; McKeown-Longo PJ; Higgins PJ
    J Cell Sci; 2001 Nov; 114(Pt 21):3905-14. PubMed ID: 11719557
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TGF-beta 1-induced PAI-1 expression is E box/USF-dependent and requires EGFR signaling.
    Kutz SM; Higgins CE; Samarakoon R; Higgins SP; Allen RR; Qi L; Higgins PJ
    Exp Cell Res; 2006 Apr; 312(7):1093-105. PubMed ID: 16457817
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Integration of non-SMAD and SMAD signaling in TGF-beta1-induced plasminogen activator inhibitor type-1 gene expression in vascular smooth muscle cells.
    Samarakoon R; Higgins PJ
    Thromb Haemost; 2008 Dec; 100(6):976-83. PubMed ID: 19132220
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MAPK/AP-1-dependent regulation of PAI-1 gene expression by TGF-beta in rat mesangial cells.
    Guo B; Inoki K; Isono M; Mori H; Kanasaki K; Sugimoto T; Akiba S; Sato T; Yang B; Kikkawa R; Kashiwagi A; Haneda M; Koya D
    Kidney Int; 2005 Sep; 68(3):972-84. PubMed ID: 16105028
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential mechanisms of plasminogen activator inhibitor-1 gene activation by transforming growth factor-beta and tumor necrosis factor-alpha in endothelial cells.
    Chen YQ; Sloan-Lancaster J; Berg DT; Richardson MA; Grinnell B; Tseng-Crank J
    Thromb Haemost; 2001 Dec; 86(6):1563-72. PubMed ID: 11776328
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Cytoskeletal Network Regulates Expression of the Profibrotic Genes PAI-1 and CTGF in Vascular Smooth Muscle Cells.
    Samarakoon R; Higgins PJ
    Adv Pharmacol; 2018; 81():79-94. PubMed ID: 29310804
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Perturbation of the actin cytoskeleton induces PAI-1 gene expression in cultured epithelial cells independent of substrate anchorage.
    Providence KM; Kutz SM; Higgins PJ
    Cell Motil Cytoskeleton; 1999; 42(3):218-29. PubMed ID: 10098935
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PAI-1 expression is required for epithelial cell migration in two distinct phases of in vitro wound repair.
    Providence KM; Higgins PJ
    J Cell Physiol; 2004 Aug; 200(2):297-308. PubMed ID: 15174100
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of plasminogen activator inhibitor-1 secretion by urokinase and tissue plasminogen activator in rat epithelioid-type smooth muscle cells.
    Lau HK; Ho J
    Br J Haematol; 2002 Apr; 117(1):151-8. PubMed ID: 11918547
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Transforming growth factor-beta1-dependent activation of Smad2/3 and up-regulation of PAI-1 expression is negatively regulated by Src in SKOV-3 human ovarian cancer cells.
    Wakahara K; Kobayashi H; Yagyu T; Matsuzaki H; Kondo T; Kurita N; Sekino H; Inagaki K; Suzuki M; Kanayama N; Terao T
    J Cell Biochem; 2004 Oct; 93(3):437-53. PubMed ID: 15372629
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Disruption of microtubules inhibits the stimulation of tissue plasminogen activator expression and promotes plasminogen activator inhibitor type 1 expression in human endothelial cells.
    Santell L; Marotti K; Bartfeld NS; Baynham P; Levin EG
    Exp Cell Res; 1992 Aug; 201(2):358-65. PubMed ID: 1639133
    [TBL] [Abstract][Full Text] [Related]  

  • 19. c-Src and hydrogen peroxide mediate transforming growth factor-beta1-induced smooth muscle cell-gene expression in 10T1/2 cells.
    Sato M; Kawai-Kowase K; Sato H; Oyama Y; Kanai H; Ohyama Y; Suga T; Maeno T; Aoki Y; Tamura J; Sakamoto H; Nagai R; Kurabayashi M
    Arterioscler Thromb Vasc Biol; 2005 Feb; 25(2):341-7. PubMed ID: 15591224
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cell-shape-dependent modulation of p52(PAI-1) gene expression involves a secondary response pathway.
    Higgins PJ; Staiano-Coico L; Ryan MP
    Biochem J; 1995 Mar; 306 ( Pt 2)(Pt 2):497-504. PubMed ID: 7887903
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.