BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

243 related articles for article (PubMed ID: 12119278)

  • 1. Role of PTEN, a lipid phosphatase upstream effector of protein kinase B, in epithelial thyroid carcinogenesis.
    Eng C
    Ann N Y Acad Sci; 2002 Jun; 968():213-21. PubMed ID: 12119278
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Germline PTEN promoter mutations and deletions in Cowden/Bannayan-Riley-Ruvalcaba syndrome result in aberrant PTEN protein and dysregulation of the phosphoinositol-3-kinase/Akt pathway.
    Zhou XP; Waite KA; Pilarski R; Hampel H; Fernandez MJ; Bos C; Dasouki M; Feldman GL; Greenberg LA; Ivanovich J; Matloff E; Patterson A; Pierpont ME; Russo D; Nassif NT; Eng C
    Am J Hum Genet; 2003 Aug; 73(2):404-11. PubMed ID: 12844284
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas.
    Kurose K; Zhou XP; Araki T; Cannistra SA; Maher ER; Eng C
    Am J Pathol; 2001 Jun; 158(6):2097-106. PubMed ID: 11395387
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The role of PTEN, a phosphatase gene, in inherited and sporadic nonmedullary thyroid tumors.
    Eng C
    Recent Prog Horm Res; 1999; 54():441-52; discussion 453. PubMed ID: 10548886
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PTEN: one gene, many syndromes.
    Eng C
    Hum Mutat; 2003 Sep; 22(3):183-98. PubMed ID: 12938083
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation.
    Marsh DJ; Coulon V; Lunetta KL; Rocca-Serra P; Dahia PL; Zheng Z; Liaw D; Caron S; Duboué B; Lin AY; Richardson AL; Bonnetblanc JM; Bressieux JM; Cabarrot-Moreau A; Chompret A; Demange L; Eeles RA; Yahanda AM; Fearon ER; Fricker JP; Gorlin RJ; Hodgson SV; Huson S; Lacombe D; Eng C
    Hum Mol Genet; 1998 Mar; 7(3):507-15. PubMed ID: 9467011
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndrome.
    Marsh DJ; Kum JB; Lunetta KL; Bennett MJ; Gorlin RJ; Ahmed SF; Bodurtha J; Crowe C; Curtis MA; Dasouki M; Dunn T; Feit H; Geraghty MT; Graham JM; Hodgson SV; Hunter A; Korf BR; Manchester D; Miesfeldt S; Murday VA; Nathanson KL; Parisi M; Pober B; Romano C; Eng C
    Hum Mol Genet; 1999 Aug; 8(8):1461-72. PubMed ID: 10400993
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Protean PTEN: form and function.
    Waite KA; Eng C
    Am J Hum Genet; 2002 Apr; 70(4):829-44. PubMed ID: 11875759
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A novel loss-of-function mutation (N48K) in the PTEN gene in a Spanish patient with Cowden disease.
    Vega A; Torres J; Torres M; Cameselle-Teijeiro J; Macia M; Carracedo A; Pulido R
    J Invest Dermatol; 2003 Dec; 121(6):1356-9. PubMed ID: 14675182
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Silencing of the PTEN tumor-suppressor gene in anaplastic thyroid cancer.
    Frisk T; Foukakis T; Dwight T; Lundberg J; Höög A; Wallin G; Eng C; Zedenius J; Larsson C
    Genes Chromosomes Cancer; 2002 Sep; 35(1):74-80. PubMed ID: 12203792
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PTEN expression is reduced in a subset of sporadic thyroid carcinomas: evidence that PTEN-growth suppressing activity in thyroid cancer cells mediated by p27kip1.
    Bruni P; Boccia A; Baldassarre G; Trapasso F; Santoro M; Chiappetta G; Fusco A; Viglietto G
    Oncogene; 2000 Jun; 19(28):3146-55. PubMed ID: 10918569
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Different splicing defects lead to differential effects downstream of the lipid and protein phosphatase activities of PTEN.
    Agrawal S; Pilarski R; Eng C
    Hum Mol Genet; 2005 Aug; 14(16):2459-68. PubMed ID: 16014636
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Constipation, polyps, or cancer? Let PTEN predict your future.
    Eng C
    Am J Med Genet A; 2003 Nov; 122A(4):315-22. PubMed ID: 14518069
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Germline inactivation of PTEN and dysregulation of the phosphoinositol-3-kinase/Akt pathway cause human Lhermitte-Duclos disease in adults.
    Zhou XP; Marsh DJ; Morrison CD; Chaudhury AR; Maxwell M; Reifenberger G; Eng C
    Am J Hum Genet; 2003 Nov; 73(5):1191-8. PubMed ID: 14566704
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Allelic imbalance, including deletion of PTEN/MMACI, at the Cowden disease locus on 10q22-23, in hamartomas from patients with Cowden syndrome and germline PTEN mutation.
    Marsh DJ; Dahia PL; Coulon V; Zheng Z; Dorion-Bonnet F; Call KM; Little R; Lin AY; Eeles RA; Goldstein AM; Hodgson SV; Richardson AL; Robinson BG; Weber HC; Longy M; Eng C
    Genes Chromosomes Cancer; 1998 Jan; 21(1):61-9. PubMed ID: 9443042
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway.
    Ramaswamy S; Nakamura N; Vazquez F; Batt DB; Perera S; Roberts TM; Sellers WR
    Proc Natl Acad Sci U S A; 1999 Mar; 96(5):2110-5. PubMed ID: 10051603
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Transient ectopic expression of PTEN in thyroid cancer cell lines induces cell cycle arrest and cell type-dependent cell death.
    Weng LP; Gimm O; Kum JB; Smith WM; Zhou XP; Wynford-Thomas D; Leone G; Eng C
    Hum Mol Genet; 2001 Feb; 10(3):251-8. PubMed ID: 11159944
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Germline PTEN mutation in a family with Cowden syndrome and Bannayan-Riley-Ruvalcaba syndrome.
    Zori RT; Marsh DJ; Graham GE; Marliss EB; Eng C
    Am J Med Genet; 1998 Dec; 80(4):399-402. PubMed ID: 9856571
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Bannayan-Riley-Ruvalcaba syndrome: further delineation of the phenotype and management of PTEN mutation-positive cases.
    Hendriks YM; Verhallen JT; van der Smagt JJ; Kant SG; Hilhorst Y; Hoefsloot L; Hansson KB; van der Straaten PJ; Boutkan H; Breuning MH; Vasen HF; Bröcker-Vriends AH
    Fam Cancer; 2003; 2(2):79-85. PubMed ID: 14574156
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Somatic deletions and mutations in the Cowden disease gene, PTEN, in sporadic thyroid tumors.
    Dahia PL; Marsh DJ; Zheng Z; Zedenius J; Komminoth P; Frisk T; Wallin G; Parsons R; Longy M; Larsson C; Eng C
    Cancer Res; 1997 Nov; 57(21):4710-3. PubMed ID: 9354427
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.