BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

246 related articles for article (PubMed ID: 12119297)

  • 1. Peptide substrate specificities and protein cleavage sites of human endometase/matrilysin-2/matrix metalloproteinase-26.
    Park HI; Turk BE; Gerkema FE; Cantley LC; Sang QX
    J Biol Chem; 2002 Sep; 277(38):35168-75. PubMed ID: 12119297
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Active site specificity profiling of the matrix metalloproteinase family: Proteomic identification of 4300 cleavage sites by nine MMPs explored with structural and synthetic peptide cleavage analyses.
    Eckhard U; Huesgen PF; Schilling O; Bellac CL; Butler GS; Cox JH; Dufour A; Goebeler V; Kappelhoff R; Keller UAD; Klein T; Lange PF; Marino G; Morrison CJ; Prudova A; Rodriguez D; Starr AE; Wang Y; Overall CM
    Matrix Biol; 2016 Jan; 49():37-60. PubMed ID: 26407638
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2, a fluorogenic substrate with increased specificity constants for collagenases and tumor necrosis factor converting enzyme.
    Neumann U; Kubota H; Frei K; Ganu V; Leppert D
    Anal Biochem; 2004 May; 328(2):166-73. PubMed ID: 15113693
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comparative sequence specificities of human 72- and 92-kDa gelatinases (type IV collagenases) and PUMP (matrilysin).
    Netzel-Arnett S; Sang QX; Moore WG; Navre M; Birkedal-Hansen H; Van Wart HE
    Biochemistry; 1993 Jun; 32(25):6427-32. PubMed ID: 8390857
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The intermediate S1' pocket of the endometase/matrilysin-2 active site revealed by enzyme inhibition kinetic studies, protein sequence analyses, and homology modeling.
    Park HI; Jin Y; Hurst DR; Monroe CA; Lee S; Schwartz MA; Sang QX
    J Biol Chem; 2003 Dec; 278(51):51646-53. PubMed ID: 14532275
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Kinetic analysis of matrix metalloproteinase activity using fluorogenic triple-helical substrates.
    Lauer-Fields JL; Broder T; Sritharan T; Chung L; Nagase H; Fields GB
    Biochemistry; 2001 May; 40(19):5795-803. PubMed ID: 11341845
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Optimization of quenched fluorescent peptide substrates of SARS-CoV-2 3CL
    Cesar Ramos de Jesus H; Solis N; Machado Y; Pablos I; Bell PA; Kappelhoff R; Grin PM; Sorgi CA; Butler GS; Overall CM
    J Virol; 2024 May; ():e0004924. PubMed ID: 38742901
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Substrate specificity of cucumisin on synthetic peptides.
    Yonezawa H; Kaizuka H; Uchikoba T; Arima K; Kaneda M
    Biosci Biotechnol Biochem; 2000 Oct; 64(10):2104-8. PubMed ID: 11129582
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Substrate specificity of human collagenase 3 assessed using a phage-displayed peptide library.
    Deng SJ; Bickett DM; Mitchell JL; Lambert MH; Blackburn RK; Carter HL; Neugebauer J; Pahel G; Weiner MP; Moss ML
    J Biol Chem; 2000 Oct; 275(40):31422-7. PubMed ID: 10906330
    [TBL] [Abstract][Full Text] [Related]  

  • 10. X-ray structures of human neutrophil collagenase complexed with peptide hydroxamate and peptide thiol inhibitors. Implications for substrate binding and rational drug design.
    Grams F; Reinemer P; Powers JC; Kleine T; Pieper M; Tschesche H; Huber R; Bode W
    Eur J Biochem; 1995 Mar; 228(3):830-41. PubMed ID: 7737183
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design and characterization of a fluorogenic substrate selectively hydrolyzed by stromelysin 1 (matrix metalloproteinase-3).
    Nagase H; Fields CG; Fields GB
    J Biol Chem; 1994 Aug; 269(33):20952-7. PubMed ID: 8063713
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Extended substrate specificity of rat mast cell protease 5, a rodent alpha-chymase with elastase-like primary specificity.
    Karlson U; Pejler G; Tomasini-Johansson B; Hellman L
    J Biol Chem; 2003 Oct; 278(41):39625-31. PubMed ID: 12900423
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification and characterization of human endometase (Matrix metalloproteinase-26) from endometrial tumor.
    Park HI; Ni J; Gerkema FE; Liu D; Belozerov VE; Sang QX
    J Biol Chem; 2000 Jul; 275(27):20540-4. PubMed ID: 10801841
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Importance of the P4' residue in human granzyme B inhibitors and substrates revealed by scanning mutagenesis of the proteinase inhibitor 9 reactive center loop.
    Sun J; Whisstock JC; Harriott P; Walker B; Novak A; Thompson PE; Smith AI; Bird PI
    J Biol Chem; 2001 May; 276(18):15177-84. PubMed ID: 11278311
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Biochemical characterization of the catalytic domain of human matrix metalloproteinase 19. Evidence for a role as a potent basement membrane degrading enzyme.
    Stracke JO; Hutton M; Stewart M; Pendás AM; Smith B; López-Otin C; Murphy G; Knäuper V
    J Biol Chem; 2000 May; 275(20):14809-16. PubMed ID: 10809722
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Substrate specificity of porcine renin: P1', P1, and P3 residues of renin substrates are crucial for activity.
    Wang W; Liang TC
    Biochemistry; 1994 Dec; 33(48):14636-41. PubMed ID: 7981226
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biochemical characterization of human collagenase-3.
    Knäuper V; López-Otin C; Smith B; Knight G; Murphy G
    J Biol Chem; 1996 Jan; 271(3):1544-50. PubMed ID: 8576151
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural determinants of procryptdin recognition and cleavage by matrix metalloproteinase-7.
    Shirafuji Y; Tanabe H; Satchell DP; Henschen-Edman A; Wilson CL; Ouellette AJ
    J Biol Chem; 2003 Mar; 278(10):7910-9. PubMed ID: 12482850
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Understanding the P1' specificity of the matrix metalloproteinases: effect of S1' pocket mutations in matrilysin and stromelysin-1.
    Welch AR; Holman CM; Huber M; Brenner MC; Browner MF; Van Wart HE
    Biochemistry; 1996 Aug; 35(31):10103-9. PubMed ID: 8756473
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of the P2' and P3' specificities of thrombin using fluorescence-quenched substrates and mapping of the subsites by mutagenesis.
    Le Bonniec BF; Myles T; Johnson T; Knight CG; Tapparelli C; Stone SR
    Biochemistry; 1996 Jun; 35(22):7114-22. PubMed ID: 8679538
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.