These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

393 related articles for article (PubMed ID: 12119423)

  • 1. Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice.
    Wyss-Coray T; Yan F; Lin AH; Lambris JD; Alexander JJ; Quigg RJ; Masliah E
    Proc Natl Acad Sci U S A; 2002 Aug; 99(16):10837-42. PubMed ID: 12119423
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Complement C3 deficiency leads to accelerated amyloid beta plaque deposition and neurodegeneration and modulation of the microglia/macrophage phenotype in amyloid precursor protein transgenic mice.
    Maier M; Peng Y; Jiang L; Seabrook TJ; Carroll MC; Lemere CA
    J Neurosci; 2008 Jun; 28(25):6333-41. PubMed ID: 18562603
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Astrocyte-Microglia Cross Talk through Complement Activation Modulates Amyloid Pathology in Mouse Models of Alzheimer's Disease.
    Lian H; Litvinchuk A; Chiang AC; Aithmitti N; Jankowsky JL; Zheng H
    J Neurosci; 2016 Jan; 36(2):577-89. PubMed ID: 26758846
    [TBL] [Abstract][Full Text] [Related]  

  • 4. High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation.
    Mucke L; Masliah E; Yu GQ; Mallory M; Rockenstein EM; Tatsuno G; Hu K; Kholodenko D; Johnson-Wood K; McConlogue L
    J Neurosci; 2000 Jun; 20(11):4050-8. PubMed ID: 10818140
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Complement C3 and C4 expression in C1q sufficient and deficient mouse models of Alzheimer's disease.
    Zhou J; Fonseca MI; Pisalyaput K; Tenner AJ
    J Neurochem; 2008 Sep; 106(5):2080-92. PubMed ID: 18624920
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice.
    Shi Q; Chowdhury S; Ma R; Le KX; Hong S; Caldarone BJ; Stevens B; Lemere CA
    Sci Transl Med; 2017 May; 9(392):. PubMed ID: 28566429
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Elimination of the class A scavenger receptor does not affect amyloid plaque formation or neurodegeneration in transgenic mice expressing human amyloid protein precursors.
    Huang F; Buttini M; Wyss-Coray T; McConlogue L; Kodama T; Pitas RE; Mucke L
    Am J Pathol; 1999 Nov; 155(5):1741-7. PubMed ID: 10550330
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Behavioral and neural network abnormalities in human APP transgenic mice resemble those of App knock-in mice and are modulated by familial Alzheimer's disease mutations but not by inhibition of BACE1.
    Johnson ECB; Ho K; Yu GQ; Das M; Sanchez PE; Djukic B; Lopez I; Yu X; Gill M; Zhang W; Paz JT; Palop JJ; Mucke L
    Mol Neurodegener; 2020 Sep; 15(1):53. PubMed ID: 32921309
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy.
    Wu T; Dejanovic B; Gandham VD; Gogineni A; Edmonds R; Schauer S; Srinivasan K; Huntley MA; Wang Y; Wang TM; Hedehus M; Barck KH; Stark M; Ngu H; Foreman O; Meilandt WJ; Elstrott J; Chang MC; Hansen DV; Carano RAD; Sheng M; Hanson JE
    Cell Rep; 2019 Aug; 28(8):2111-2123.e6. PubMed ID: 31433986
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation of the nuclear receptor PPARδ is neuroprotective in a transgenic mouse model of Alzheimer's disease through inhibition of inflammation.
    Malm T; Mariani M; Donovan LJ; Neilson L; Landreth GE
    J Neuroinflammation; 2015 Jan; 12():7. PubMed ID: 25592770
    [TBL] [Abstract][Full Text] [Related]  

  • 11. TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice.
    Wyss-Coray T; Lin C; Yan F; Yu GQ; Rohde M; McConlogue L; Masliah E; Mucke L
    Nat Med; 2001 May; 7(5):612-8. PubMed ID: 11329064
    [TBL] [Abstract][Full Text] [Related]  

  • 12. IFN-γ Production by amyloid β-specific Th1 cells promotes microglial activation and increases plaque burden in a mouse model of Alzheimer's disease.
    Browne TC; McQuillan K; McManus RM; O'Reilly JA; Mills KH; Lynch MA
    J Immunol; 2013 Mar; 190(5):2241-51. PubMed ID: 23365075
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cathepsin B degrades amyloid-β in mice expressing wild-type human amyloid precursor protein.
    Wang C; Sun B; Zhou Y; Grubb A; Gan L
    J Biol Chem; 2012 Nov; 287(47):39834-41. PubMed ID: 23024364
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation.
    Buttini M; Yu GQ; Shockley K; Huang Y; Jones B; Masliah E; Mallory M; Yeo T; Longo FM; Mucke L
    J Neurosci; 2002 Dec; 22(24):10539-48. PubMed ID: 12486146
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Fyn kinase modulates synaptotoxicity, but not aberrant sprouting, in human amyloid precursor protein transgenic mice.
    Chin J; Palop JJ; Yu GQ; Kojima N; Masliah E; Mucke L
    J Neurosci; 2004 May; 24(19):4692-7. PubMed ID: 15140940
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Defined astrocytic expression of human amyloid precursor protein in Tg2576 mouse brain.
    Heiland T; Zeitschel U; Puchades MA; Kuhn PH; Lichtenthaler SF; Bjaalie JG; Hartlage-Rübsamen M; Roßner S; Höfling C
    Glia; 2019 Feb; 67(2):393-403. PubMed ID: 30485540
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Microglial C5aR (CD88) expression correlates with amyloid-beta deposition in murine models of Alzheimer's disease.
    Ager RR; Fonseca MI; Chu SH; Sanderson SD; Taylor SM; Woodruff TM; Tenner AJ
    J Neurochem; 2010 Apr; 113(2):389-401. PubMed ID: 20132482
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Contribution of complement activation pathways to neuropathology differs among mouse models of Alzheimer's disease.
    Fonseca MI; Chu SH; Berci AM; Benoit ME; Peters DG; Kimura Y; Tenner AJ
    J Neuroinflammation; 2011 Jan; 8(1):4. PubMed ID: 21235806
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Astroglial expression of human alpha(1)-antichymotrypsin enhances alzheimer-like pathology in amyloid protein precursor transgenic mice.
    Mucke L; Yu GQ; McConlogue L; Rockenstein EM; Abraham CR; Masliah E
    Am J Pathol; 2000 Dec; 157(6):2003-10. PubMed ID: 11106573
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Chronic apocynin treatment attenuates beta amyloid plaque size and microglial number in hAPP(751)(SL) mice.
    Lull ME; Levesque S; Surace MJ; Block ML
    PLoS One; 2011; 6(5):e20153. PubMed ID: 21655287
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.