BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

524 related articles for article (PubMed ID: 12120097)

  • 1. Metabonomics: a platform for studying drug toxicity and gene function.
    Nicholson JK; Connelly J; Lindon JC; Holmes E
    Nat Rev Drug Discov; 2002 Feb; 1(2):153-61. PubMed ID: 12120097
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Prediction and classification of drug toxicity using probabilistic modeling of temporal metabolic data: the consortium on metabonomic toxicology screening approach.
    Ebbels TM; Keun HC; Beckonert OP; Bollard ME; Lindon JC; Holmes E; Nicholson JK
    J Proteome Res; 2007 Nov; 6(11):4407-22. PubMed ID: 17915905
    [TBL] [Abstract][Full Text] [Related]  

  • 3. [Development of antituberculous drugs: current status and future prospects].
    Tomioka H; Namba K
    Kekkaku; 2006 Dec; 81(12):753-74. PubMed ID: 17240921
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel genomic methods for drug discovery and mechanism-based toxicological assessment.
    Gant TW; Zhang SD; Taylor EL
    Curr Opin Drug Discov Devel; 2009 Jan; 12(1):72-80. PubMed ID: 19152215
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Testing paradigm for prediction of development-limiting barriers and human drug toxicity.
    Sasseville VG; Lane JH; Kadambi VJ; Bouchard P; Lee FW; Balani SK; Miwa GT; Smith PF; Alden CL
    Chem Biol Interact; 2004 Nov; 150(1):9-25. PubMed ID: 15522258
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Alternative strategies in drug development: clinical pharmacological aspects.
    Kuhlmann J
    Int J Clin Pharmacol Ther; 1999 Dec; 37(12):575-83. PubMed ID: 10599949
    [TBL] [Abstract][Full Text] [Related]  

  • 7. State-of-the-art genomics approaches in toxicology.
    Van Hummelen P; Sasaki J
    Mutat Res; 2010 Dec; 705(3):165-71. PubMed ID: 20466069
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Metabonomics: a useful tool for the future surgeon.
    Goldsmith P; Fenton H; Morris-Stiff G; Ahmad N; Fisher J; Prasad KR
    J Surg Res; 2010 May; 160(1):122-32. PubMed ID: 19592031
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Computational toxicology in drug development.
    Muster W; Breidenbach A; Fischer H; Kirchner S; Müller L; Pähler A
    Drug Discov Today; 2008 Apr; 13(7-8):303-10. PubMed ID: 18405842
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Toxicogenomics in the pharmaceutical industry: hollow promises or real benefit?
    Lühe A; Suter L; Ruepp S; Singer T; Weiser T; Albertini S
    Mutat Res; 2005 Aug; 575(1-2):102-15. PubMed ID: 15924886
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Predictive toxicogenomics in preclinical discovery.
    Barros SA; Martin RB
    Methods Mol Biol; 2008; 460():89-112. PubMed ID: 18449484
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Metabonomics technologies and their applications in physiological monitoring, drug safety assessment and disease diagnosis.
    Lindon JC; Holmes E; Bollard ME; Stanley EG; Nicholson JK
    Biomarkers; 2004; 9(1):1-31. PubMed ID: 15204308
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Use of metabonomics to identify impaired fatty acid metabolism as the mechanism of a drug-induced toxicity.
    Mortishire-Smith RJ; Skiles GL; Lawrence JW; Spence S; Nicholls AW; Johnson BA; Nicholson JK
    Chem Res Toxicol; 2004 Feb; 17(2):165-73. PubMed ID: 14967004
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Transcriptomics in predictive toxicology.
    Storck T; von Brevern MC; Behrens CK; Scheel J; Bach A
    Curr Opin Drug Discov Devel; 2002 Jan; 5(1):90-7. PubMed ID: 11865677
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vivo toxicity screening programs using metabonomics.
    Robosky LC; Robertson DG; Baker JD; Rane S; Reily MD
    Comb Chem High Throughput Screen; 2002 Dec; 5(8):651-62. PubMed ID: 12470262
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Toxicogenomics in biomarker discovery.
    Decristofaro MF; Daniels KK
    Methods Mol Biol; 2008; 460():185-94. PubMed ID: 18449488
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NMR-based metabolic profiling and metabonomic approaches to problems in molecular toxicology.
    Coen M; Holmes E; Lindon JC; Nicholson JK
    Chem Res Toxicol; 2008 Jan; 21(1):9-27. PubMed ID: 18171018
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Towards quantitative biology: integration of biological information to elucidate disease pathways and to guide drug discovery.
    Fischer HP
    Biotechnol Annu Rev; 2005; 11():1-68. PubMed ID: 16216773
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Development of a large-scale chemogenomics database to improve drug candidate selection and to understand mechanisms of chemical toxicity and action.
    Ganter B; Tugendreich S; Pearson CI; Ayanoglu E; Baumhueter S; Bostian KA; Brady L; Browne LJ; Calvin JT; Day GJ; Breckenridge N; Dunlea S; Eynon BP; Furness LM; Ferng J; Fielden MR; Fujimoto SY; Gong L; Hu C; Idury R; Judo MS; Kolaja KL; Lee MD; McSorley C; Minor JM; Nair RV; Natsoulis G; Nguyen P; Nicholson SM; Pham H; Roter AH; Sun D; Tan S; Thode S; Tolley AM; Vladimirova A; Yang J; Zhou Z; Jarnagin K
    J Biotechnol; 2005 Sep; 119(3):219-44. PubMed ID: 16005536
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The application of discovery toxicology and pathology towards the design of safer pharmaceutical lead candidates.
    Kramer JA; Sagartz JE; Morris DL
    Nat Rev Drug Discov; 2007 Aug; 6(8):636-49. PubMed ID: 17643090
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 27.