556 related articles for article (PubMed ID: 12120277)
1. PXR, CAR and drug metabolism.
Willson TM; Kliewer SA
Nat Rev Drug Discov; 2002 Apr; 1(4):259-66. PubMed ID: 12120277
[TBL] [Abstract][Full Text] [Related]
2. Regulation of cyp3a gene transcription by the pregnane x receptor.
Goodwin B; Redinbo MR; Kliewer SA
Annu Rev Pharmacol Toxicol; 2002; 42():1-23. PubMed ID: 11807162
[TBL] [Abstract][Full Text] [Related]
3. Regulation of the human CYP2B6 gene by the nuclear pregnane X receptor.
Goodwin B; Moore LB; Stoltz CM; McKee DD; Kliewer SA
Mol Pharmacol; 2001 Sep; 60(3):427-31. PubMed ID: 11502872
[TBL] [Abstract][Full Text] [Related]
4. The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism.
Kliewer SA; Goodwin B; Willson TM
Endocr Rev; 2002 Oct; 23(5):687-702. PubMed ID: 12372848
[TBL] [Abstract][Full Text] [Related]
5. Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification.
Maglich JM; Stoltz CM; Goodwin B; Hawkins-Brown D; Moore JT; Kliewer SA
Mol Pharmacol; 2002 Sep; 62(3):638-46. PubMed ID: 12181440
[TBL] [Abstract][Full Text] [Related]
6. Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands.
Moore LB; Parks DJ; Jones SA; Bledsoe RK; Consler TG; Stimmel JB; Goodwin B; Liddle C; Blanchard SG; Willson TM; Collins JL; Kliewer SA
J Biol Chem; 2000 May; 275(20):15122-7. PubMed ID: 10748001
[TBL] [Abstract][Full Text] [Related]
7. Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR.
Xie W; Barwick JL; Simon CM; Pierce AM; Safe S; Blumberg B; Guzelian PS; Evans RM
Genes Dev; 2000 Dec; 14(23):3014-23. PubMed ID: 11114890
[TBL] [Abstract][Full Text] [Related]
8. Reduction in cytochrome P-450 enzyme expression is associated with repression of CAR (constitutive androstane receptor) and PXR (pregnane X receptor) in mouse liver during the acute phase response.
Beigneux AP; Moser AH; Shigenaga JK; Grunfeld C; Feingold KR
Biochem Biophys Res Commun; 2002 Apr; 293(1):145-9. PubMed ID: 12054576
[TBL] [Abstract][Full Text] [Related]
9. Role of orphan nuclear receptors in the regulation of drug-metabolising enzymes.
Wang H; LeCluyse EL
Clin Pharmacokinet; 2003; 42(15):1331-57. PubMed ID: 14674787
[TBL] [Abstract][Full Text] [Related]
10. Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor.
Staudinger J; Liu Y; Madan A; Habeebu S; Klaassen CD
Drug Metab Dispos; 2001 Nov; 29(11):1467-72. PubMed ID: 11602523
[TBL] [Abstract][Full Text] [Related]
11. The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution.
Jones SA; Moore LB; Shenk JL; Wisely GB; Hamilton GA; McKee DD; Tomkinson NC; LeCluyse EL; Lambert MH; Willson TM; Kliewer SA; Moore JT
Mol Endocrinol; 2000 Jan; 14(1):27-39. PubMed ID: 10628745
[TBL] [Abstract][Full Text] [Related]
12. Humanized xenobiotic response in mice expressing nuclear receptor SXR.
Xie W; Barwick JL; Downes M; Blumberg B; Simon CM; Nelson MC; Neuschwander-Tetri BA; Brunt EM; Guzelian PS; Evans RM
Nature; 2000 Jul; 406(6794):435-9. PubMed ID: 10935643
[TBL] [Abstract][Full Text] [Related]
13. Transcriptional regulation of cytochrome p450 2B genes by nuclear receptors.
Wang H; Negishi M
Curr Drug Metab; 2003 Dec; 4(6):515-25. PubMed ID: 14683479
[TBL] [Abstract][Full Text] [Related]
14. Pharmaceutical use of mouse models humanized for the xenobiotic receptor.
Xie W; Evans RM
Drug Discov Today; 2002 May; 7(9):509-15. PubMed ID: 11983567
[TBL] [Abstract][Full Text] [Related]
15. CAR/PXR provide directives for Cyp3a41 gene regulation differently from Cyp3a11.
Anakk S; Kalsotra A; Kikuta Y; Huang W; Zhang J; Staudinger JL; Moore DD; Strobel HW
Pharmacogenomics J; 2004; 4(2):91-101. PubMed ID: 14770174
[TBL] [Abstract][Full Text] [Related]
16. Mechanisms of cytochrome P450 induction.
Tompkins LM; Wallace AD
J Biochem Mol Toxicol; 2007; 21(4):176-81. PubMed ID: 17936931
[TBL] [Abstract][Full Text] [Related]
17. The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants.
Zhang J; Kuehl P; Green ED; Touchman JW; Watkins PB; Daly A; Hall SD; Maurel P; Relling M; Brimer C; Yasuda K; Wrighton SA; Hancock M; Kim RB; Strom S; Thummel K; Russell CG; Hudson JR; Schuetz EG; Boguski MS
Pharmacogenetics; 2001 Oct; 11(7):555-72. PubMed ID: 11668216
[TBL] [Abstract][Full Text] [Related]
18. The xenobiotic-sensing nuclear receptors pregnane X receptor, constitutive androstane receptor, and orphan nuclear receptor hepatocyte nuclear factor 4alpha in the regulation of human steroid-/bile acid-sulfotransferase.
Echchgadda I; Song CS; Oh T; Ahmed M; De La Cruz IJ; Chatterjee B
Mol Endocrinol; 2007 Sep; 21(9):2099-111. PubMed ID: 17595319
[TBL] [Abstract][Full Text] [Related]
19. Regulation of drug transporter gene expression by nuclear receptors.
Staudinger JL; Madan A; Carol KM; Parkinson A
Drug Metab Dispos; 2003 May; 31(5):523-7. PubMed ID: 12695338
[TBL] [Abstract][Full Text] [Related]
20. Dual role of orphan nuclear receptor pregnane X receptor in bilirubin detoxification in mice.
Saini SP; Mu Y; Gong H; Toma D; Uppal H; Ren S; Li S; Poloyac SM; Xie W
Hepatology; 2005 Mar; 41(3):497-505. PubMed ID: 15726644
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
