BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

237 related articles for article (PubMed ID: 12121224)

  • 1. Possible mechanism for the alpha subunit of the interleukin-2 receptor (CD25) to influence interleukin-2 receptor signal transduction.
    Ellery JM; Nicholls PJ
    Immunol Cell Biol; 2002 Aug; 80(4):351-7. PubMed ID: 12121224
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits.
    Miyazaki T; Kawahara A; Fujii H; Nakagawa Y; Minami Y; Liu ZJ; Oishi I; Silvennoinen O; Witthuhn BA; Ihle JN
    Science; 1994 Nov; 266(5187):1045-7. PubMed ID: 7973659
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Staphylococcal enterotoxins modulate interleukin 2 receptor expression and ligand-induced tyrosine phosphorylation of the Janus protein-tyrosine kinase 3 (Jak3) and signal transducers and activators of transcription (Stat proteins).
    Nielsen M; Svejgaard A; Röpke C; Nordahl M; Odum N
    Proc Natl Acad Sci U S A; 1995 Nov; 92(24):10995-9. PubMed ID: 7479924
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation of JAK3, but not JAK1, is critical for IL-2-induced proliferation and STAT5 recruitment by a COOH-terminal region of the IL-2 receptor beta-chain.
    Kirken RA; Rui H; Malabarba MG; Howard OM; Kawamura M; O'Shea JJ; Farrar WL
    Cytokine; 1995 Oct; 7(7):689-700. PubMed ID: 8580378
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A membrane-proximal region of the interleukin-2 receptor gamma c chain sufficient for Jak kinase activation and induction of proliferation in T cells.
    Nelson BH; Lord JD; Greenberg PD
    Mol Cell Biol; 1996 Jan; 16(1):309-17. PubMed ID: 8524310
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor beta chain but is not essential for the proliferative signal transmission.
    Fujii H; Nakagawa Y; Schindler U; Kawahara A; Mori H; Gouilleux F; Groner B; Ihle JN; Minami Y; Miyazaki T
    Proc Natl Acad Sci U S A; 1995 Jun; 92(12):5482-6. PubMed ID: 7777534
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Time-Dependent Regulation of IL-2R α-Chain (CD25) Expression by TCR Signal Strength and IL-2-Induced STAT5 Signaling in Activated Human Blood T Lymphocytes.
    Shatrova AN; Mityushova EV; Vassilieva IO; Aksenov ND; Zenin VV; Nikolsky NN; Marakhova II
    PLoS One; 2016; 11(12):e0167215. PubMed ID: 27936140
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Alternate signalling pathways from the interleukin-2 receptor.
    Ellery JM; Nicholls PJ
    Cytokine Growth Factor Rev; 2002 Feb; 13(1):27-40. PubMed ID: 11750878
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Requirement for an initial signal from the membrane-proximal region of the interleukin 2 receptor gamma(c) chain for Janus kinase activation leading to T cell proliferation.
    Nelson BH; McIntosh BC; Rosencrans LL; Greenberg PD
    Proc Natl Acad Sci U S A; 1997 Mar; 94(5):1878-83. PubMed ID: 9050873
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Critical role of the interleukin 2 (IL-2) receptor gamma-chain-associated Jak3 in the IL-2-induced c-fos and c-myc, but not bcl-2, gene induction.
    Kawahara A; Minami Y; Miyazaki T; Ihle JN; Taniguchi T
    Proc Natl Acad Sci U S A; 1995 Sep; 92(19):8724-8. PubMed ID: 7568005
    [TBL] [Abstract][Full Text] [Related]  

  • 11. GPI-microdomains (membrane rafts) and signaling of the multi-chain interleukin-2 receptor in human lymphoma/leukemia T cell lines.
    Matkó J; Bodnár A; Vereb G; Bene L; Vámosi G; Szentesi G; Szöllösi J; Gáspár R; Horejsi V; Waldmann TA; Damjanovich S
    Eur J Biochem; 2002 Feb; 269(4):1199-208. PubMed ID: 11856346
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Critical role of the membrane-proximal, proline-rich motif of the interleukin-2 receptor gammac chain in the Jak3-independent signal transduction.
    Tsujino S; Miyazaki T; Kawahara A; Maeda M; Taniguchi T; Fujii H
    Genes Cells; 1999 Jun; 4(6):363-73. PubMed ID: 10421845
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dispensability of Jak1 tyrosine kinase for interleukin-2-induced cell growth signaling in a human T cell line.
    Higuchi M; Asao H; Tanaka N; Oda K; Takeshita T; Nakamura M; Van Snick J; Sugamura K
    Eur J Immunol; 1996 Jun; 26(6):1322-7. PubMed ID: 8647212
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of the interleukin 2 receptors (IL-2R) expressed on human natural killer cells activated in vivo by IL-2: association of the p64 IL-2R gamma chain with the IL-2R beta chain in functional intermediate-affinity IL-2R.
    Voss SD; Sondel PM; Robb RJ
    J Exp Med; 1992 Aug; 176(2):531-41. PubMed ID: 1500859
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interaction of IL-15 with the shared IL-2 receptor beta and gamma c subunits. The IL-15/beta/gamma c receptor-ligand complex is less stable than the IL-2/beta/gamma c receptor-ligand complex.
    de Jong JL; Farner NL; Widmer MB; Giri JG; Sondel PM
    J Immunol; 1996 Feb; 156(4):1339-48. PubMed ID: 8568232
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Biology of the interleukin-2 receptor.
    Nelson BH; Willerford DM
    Adv Immunol; 1998; 70():1-81. PubMed ID: 9755337
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Efficient internalization of IL-2 depends on the distal portion of the cytoplasmic tail of the IL-2R common gamma-chain and a lymphoid cell environment.
    Yu A; Olosz F; Choi CY; Malek TR
    J Immunol; 2000 Sep; 165(5):2556-62. PubMed ID: 10946282
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of the interleukin 2 receptor: a possible role for tyrosine phosphatases.
    Ellery JM; Kempshall SJ; Nicholls PJ
    Cell Signal; 2000 Jun; 12(6):367-73. PubMed ID: 10889465
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Anti-apoptotic signaling by the interleukin-2 receptor reveals a function for cytoplasmic tyrosine residues within the common gamma (gamma c) receptor subunit.
    Lindemann MJ; Benczik M; Gaffen SL
    J Biol Chem; 2003 Mar; 278(12):10239-49. PubMed ID: 12525482
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interleukin-15 up-regulates interleukin-2 receptor alpha chain but down-regulates its own high-affinity binding sites on human T and B cells.
    Kumaki S; Armitage R; Ahdieh M; Park L; Cosman D
    Eur J Immunol; 1996 Jun; 26(6):1235-9. PubMed ID: 8647198
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.