438 related articles for article (PubMed ID: 12121969)
1. Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro.
MacFarlane M; Merrison W; Bratton SB; Cohen GM
J Biol Chem; 2002 Sep; 277(39):36611-6. PubMed ID: 12121969
[TBL] [Abstract][Full Text] [Related]
2. X-linked inhibitor of apoptosis (XIAP) blocks Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of prostate cancer cells in the presence of mitochondrial activation: sensitization by overexpression of second mitochondria-derived activator of caspase/direct IAP-binding protein with low pl (Smac/DIABLO).
Ng CP; Bonavida B
Mol Cancer Ther; 2002 Oct; 1(12):1051-8. PubMed ID: 12481428
[TBL] [Abstract][Full Text] [Related]
3. Smac3, a novel Smac/DIABLO splicing variant, attenuates the stability and apoptosis-inhibiting activity of X-linked inhibitor of apoptosis protein.
Fu J; Jin Y; Arend LJ
J Biol Chem; 2003 Dec; 278(52):52660-72. PubMed ID: 14523016
[TBL] [Abstract][Full Text] [Related]
4. Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of human melanoma is regulated by smac/DIABLO release from mitochondria.
Zhang XD; Zhang XY; Gray CP; Nguyen T; Hersey P
Cancer Res; 2001 Oct; 61(19):7339-48. PubMed ID: 11585775
[TBL] [Abstract][Full Text] [Related]
5. Bax/Bak-dependent, Drp1-independent Targeting of X-linked Inhibitor of Apoptosis Protein (XIAP) into Inner Mitochondrial Compartments Counteracts Smac/DIABLO-dependent Effector Caspase Activation.
Hamacher-Brady A; Brady NR
J Biol Chem; 2015 Sep; 290(36):22005-18. PubMed ID: 26134559
[TBL] [Abstract][Full Text] [Related]
6. X-linked inhibitor of apoptosis functions as ubiquitin ligase toward mature caspase-9 and cytosolic Smac/DIABLO.
Morizane Y; Honda R; Fukami K; Yasuda H
J Biochem; 2005 Feb; 137(2):125-32. PubMed ID: 15749826
[TBL] [Abstract][Full Text] [Related]
7. Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway.
Srinivasula SM; Datta P; Fan XJ; Fernandes-Alnemri T; Huang Z; Alnemri ES
J Biol Chem; 2000 Nov; 275(46):36152-7. PubMed ID: 10950947
[TBL] [Abstract][Full Text] [Related]
8. Smac/DIABLO selectively reduces the levels of c-IAP1 and c-IAP2 but not that of XIAP and livin in HeLa cells.
Yang QH; Du C
J Biol Chem; 2004 Apr; 279(17):16963-70. PubMed ID: 14960576
[TBL] [Abstract][Full Text] [Related]
9. Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative-(BMS 247550) and Apo-2L/TRAIL-induced apoptosis.
Guo F; Nimmanapalli R; Paranawithana S; Wittman S; Griffin D; Bali P; O'Bryan E; Fumero C; Wang HG; Bhalla K
Blood; 2002 May; 99(9):3419-26. PubMed ID: 11964312
[TBL] [Abstract][Full Text] [Related]
10. X-linked inhibitor regulating TRAIL-induced apoptosis in chemoresistant human primary glioblastoma cells.
Roa WH; Chen H; Fulton D; Gulavita S; Shaw A; Th'ng J; Farr-Jones M; Moore R; Petruk K
Clin Invest Med; 2003 Oct; 26(5):231-42. PubMed ID: 14596484
[TBL] [Abstract][Full Text] [Related]
11. Activation of ERK1/2 protects melanoma cells from TRAIL-induced apoptosis by inhibiting Smac/DIABLO release from mitochondria.
Zhang XD; Borrow JM; Zhang XY; Nguyen T; Hersey P
Oncogene; 2003 May; 22(19):2869-81. PubMed ID: 12771938
[TBL] [Abstract][Full Text] [Related]
12. Direct interaction of Smac with NADE promotes TRAIL-induced apoptosis.
Yoon K; Jang HD; Lee SY
Biochem Biophys Res Commun; 2004 Jun; 319(2):649-54. PubMed ID: 15178455
[TBL] [Abstract][Full Text] [Related]
13. Potent antileukemic interactions between flavopiridol and TRAIL/Apo2L involve flavopiridol-mediated XIAP downregulation.
Rosato RR; Dai Y; Almenara JA; Maggio SC; Grant S
Leukemia; 2004 Nov; 18(11):1780-8. PubMed ID: 15385934
[TBL] [Abstract][Full Text] [Related]
14. Unlike Diablo/smac, Grim promotes global ubiquitination and specific degradation of X chromosome-linked inhibitor of apoptosis (XIAP) and neither cause apoptosis.
Silke J; Kratina T; Ekert PG; Pakusch M; Vaux DL
J Biol Chem; 2004 Feb; 279(6):4313-21. PubMed ID: 14570909
[TBL] [Abstract][Full Text] [Related]
15. A novel ubiquitin fusion system bypasses the mitochondria and generates biologically active Smac/DIABLO.
Hunter AM; Kottachchi D; Lewis J; Duckett CS; Korneluk RG; Liston P
J Biol Chem; 2003 Feb; 278(9):7494-9. PubMed ID: 12511567
[TBL] [Abstract][Full Text] [Related]
16. Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death.
Suzuki Y; Nakabayashi Y; Takahashi R
Proc Natl Acad Sci U S A; 2001 Jul; 98(15):8662-7. PubMed ID: 11447297
[TBL] [Abstract][Full Text] [Related]
17. Intramitochondrial recruitment of endolysosomes mediates Smac degradation and constitutes a novel intrinsic apoptosis antagonizing function of XIAP E3 ligase.
Hamacher-Brady A; Choe SC; Krijnse-Locker J; Brady NR
Cell Death Differ; 2014 Dec; 21(12):1862-76. PubMed ID: 25080938
[TBL] [Abstract][Full Text] [Related]
18. Smac/Diablo antagonizes ubiquitin ligase activity of inhibitor of apoptosis proteins.
Creagh EM; Murphy BM; Duriez PJ; Duckett CS; Martin SJ
J Biol Chem; 2004 Jun; 279(26):26906-14. PubMed ID: 15078891
[TBL] [Abstract][Full Text] [Related]
19. Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis is inhibited by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human colon cancer cells.
Sinicrope FA; Penington RC; Tang XM
Clin Cancer Res; 2004 Dec; 10(24):8284-92. PubMed ID: 15623604
[TBL] [Abstract][Full Text] [Related]
20. Synergy is achieved by complementation with Apo2L/TRAIL and actinomycin D in Apo2L/TRAIL-mediated apoptosis of prostate cancer cells: role of XIAP in resistance.
Ng CP; Zisman A; Bonavida B
Prostate; 2002 Dec; 53(4):286-99. PubMed ID: 12430140
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
