BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 12122119)

  • 1. The MEKK1-JNK pathway plays a protective role in pressure overload but does not mediate cardiac hypertrophy.
    Sadoshima J; Montagne O; Wang Q; Yang G; Warden J; Liu J; Takagi G; Karoor V; Hong C; Johnson GL; Vatner DE; Vatner SF
    J Clin Invest; 2002 Jul; 110(2):271-9. PubMed ID: 12122119
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MEKK1 is essential for cardiac hypertrophy and dysfunction induced by Gq.
    Minamino T; Yujiri T; Terada N; Taffet GE; Michael LH; Johnson GL; Schneider MD
    Proc Natl Acad Sci U S A; 2002 Mar; 99(6):3866-71. PubMed ID: 11891332
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Potentiation of apoptosis by low dose stress stimuli in cells expressing activated MEK kinase 1.
    Widmann C; Johnson NL; Gardner AM; Smith RJ; Johnson GL
    Oncogene; 1997 Nov; 15(20):2439-47. PubMed ID: 9395240
    [TBL] [Abstract][Full Text] [Related]  

  • 4. AMP activated protein kinase-alpha2 deficiency exacerbates pressure-overload-induced left ventricular hypertrophy and dysfunction in mice.
    Zhang P; Hu X; Xu X; Fassett J; Zhu G; Viollet B; Xu W; Wiczer B; Bernlohr DA; Bache RJ; Chen Y
    Hypertension; 2008 Nov; 52(5):918-24. PubMed ID: 18838626
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mitogen-activated protein kinases (p38 and c-Jun NH2-terminal kinase) are differentially regulated during cardiac volume and pressure overload hypertrophy.
    Sopontammarak S; Aliharoob A; Ocampo C; Arcilla RA; Gupta MP; Gupta M
    Cell Biochem Biophys; 2005; 43(1):61-76. PubMed ID: 16043884
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MEKK1-induced apoptosis requires TRAIL death receptor activation and is inhibited by AKT/PKB through inhibition of MEKK1 cleavage.
    Bild AH; Mendoza FJ; Gibson EM; Huang M; Villanueva J; Garrington TP; Jove R; Johnson GL; Gibson SB
    Oncogene; 2002 Sep; 21(43):6649-56. PubMed ID: 12242663
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A role for MEK kinase 1 in TGF-beta/activin-induced epithelium movement and embryonic eyelid closure.
    Zhang L; Wang W; Hayashi Y; Jester JV; Birk DE; Gao M; Liu CY; Kao WW; Karin M; Xia Y
    EMBO J; 2003 Sep; 22(17):4443-54. PubMed ID: 12941696
    [TBL] [Abstract][Full Text] [Related]  

  • 8. MEKK1 induces c-Jun complexes that act as negative regulators for cell survival and proliferation of HCC cells.
    Komoda F; Shino Y; Hirano T; Okutomi Y; Okamoto H; Hayashi Y; Suyama T; Ebara M; Saisho H; Shirasawa H
    Int J Oncol; 2002 Sep; 21(3):553-9. PubMed ID: 12168099
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pressure-mediated hypertrophy and mechanical stretch induces IL-1 release and subsequent IGF-1 generation to maintain compensative hypertrophy by affecting Akt and JNK pathways.
    Honsho S; Nishikawa S; Amano K; Zen K; Adachi Y; Kishita E; Matsui A; Katsume A; Yamaguchi S; Nishikawa K; Isoda K; Riches DW; Matoba S; Okigaki M; Matsubara H
    Circ Res; 2009 Nov; 105(11):1149-58. PubMed ID: 19834007
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cathepsin B deficiency attenuates cardiac remodeling in response to pressure overload via TNF-α/ASK1/JNK pathway.
    Wu QQ; Xu M; Yuan Y; Li FF; Yang Z; Liu Y; Zhou MQ; Bian ZY; Deng W; Gao L; Li H; Tang QZ
    Am J Physiol Heart Circ Physiol; 2015 May; 308(9):H1143-54. PubMed ID: 25713304
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tumor necrosis factor-alpha mediates cardiac remodeling and ventricular dysfunction after pressure overload state.
    Sun M; Chen M; Dawood F; Zurawska U; Li JY; Parker T; Kassiri Z; Kirshenbaum LA; Arnold M; Khokha R; Liu PP
    Circulation; 2007 Mar; 115(11):1398-407. PubMed ID: 17353445
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Src and multiple MAP kinase activation in cardiac hypertrophy and congestive heart failure under chronic pressure-overload: comparison with acute mechanical stretch.
    Takeishi Y; Huang Q; Abe J; Glassman M; Che W; Lee JD; Kawakatsu H; Lawrence EG; Hoit BD; Berk BC; Walsh RA
    J Mol Cell Cardiol; 2001 Sep; 33(9):1637-48. PubMed ID: 11549343
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Induction of mitogen-activated protein kinases is proportional to the amount of pressure overload.
    Esposito G; Perrino C; Schiattarella GG; Belardo L; di Pietro E; Franzone A; Capretti G; Gargiulo G; Pironti G; Cannavo A; Sannino A; Izzo R; Chiariello M
    Hypertension; 2010 Jan; 55(1):137-43. PubMed ID: 19901160
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The antioxidant edaravone attenuates pressure overload-induced left ventricular hypertrophy.
    Tsujimoto I; Hikoso S; Yamaguchi O; Kashiwase K; Nakai A; Takeda T; Watanabe T; Taniike M; Matsumura Y; Nishida K; Hori M; Kogo M; Otsu K
    Hypertension; 2005 May; 45(5):921-6. PubMed ID: 15824197
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Raloxifene prevents cardiac hypertrophy and dysfunction in pressure-overloaded mice.
    Ogita H; Node K; Liao Y; Ishikura F; Beppu S; Asanuma H; Sanada S; Takashima S; Minamino T; Hori M; Kitakaze M
    Hypertension; 2004 Feb; 43(2):237-42. PubMed ID: 14676219
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The c-Jun N-terminal kinase cascade plays a role in stress-induced apoptosis in Jurkat cells by up-regulating Fas ligand expression.
    Faris M; Kokot N; Latinis K; Kasibhatla S; Green DR; Koretzky GA; Nel A
    J Immunol; 1998 Jan; 160(1):134-44. PubMed ID: 9551965
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation.
    Yujiri T; Ware M; Widmann C; Oyer R; Russell D; Chan E; Zaitsu Y; Clarke P; Tyler K; Oka Y; Fanger GR; Henson P; Johnson GL
    Proc Natl Acad Sci U S A; 2000 Jun; 97(13):7272-7. PubMed ID: 10852963
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Raf-1 kinase is required for cardiac hypertrophy and cardiomyocyte survival in response to pressure overload.
    Harris IS; Zhang S; Treskov I; Kovacs A; Weinheimer C; Muslin AJ
    Circulation; 2004 Aug; 110(6):718-23. PubMed ID: 15289381
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Basigin Promotes Cardiac Fibrosis and Failure in Response to Chronic Pressure Overload in Mice.
    Suzuki K; Satoh K; Ikeda S; Sunamura S; Otsuki T; Satoh T; Kikuchi N; Omura J; Kurosawa R; Nogi M; Numano K; Sugimura K; Aoki T; Tatebe S; Miyata S; Mukherjee R; Spinale FG; Kadomatsu K; Shimokawa H
    Arterioscler Thromb Vasc Biol; 2016 Apr; 36(4):636-46. PubMed ID: 26916734
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MK5 haplodeficiency attenuates hypertrophy and preserves diastolic function during remodeling induced by chronic pressure overload in the mouse heart.
    Nawaito SA; Dingar D; Sahadevan P; Hussein B; Sahmi F; Shi Y; Gillis MA; Gaestel M; Tardif JC; Allen BG
    Am J Physiol Heart Circ Physiol; 2017 Jul; 313(1):H46-H58. PubMed ID: 28432058
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.