These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Microsomal monooxygenation of the carcinostatic 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea. Synthesis and identification of cis and trans monohydroxylated products. May HE; Boose R; Reed DJ Biochemistry; 1975 Oct; 14(21):4723-30. PubMed ID: 1182112 [TBL] [Abstract][Full Text] [Related]
3. Stereoselective monooxygenation of carcinostatic 1-(2-chloroethyl)-3-(cyclohexyl)-1-nitrosourea and 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea by purified cytochrome P-450 isozymes. Potter DW; Levin W; Ryan DE; Thomas PE; Reed DJ Biochem Pharmacol; 1984 Feb; 33(4):609-13. PubMed ID: 6704177 [TBL] [Abstract][Full Text] [Related]
4. Synthesis, metabolism, and antitumor activity of deuterated analogues of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea. Farmer PB; Foster AB; Jarman M; Oddy MR; Reed DJ J Med Chem; 1978 Jun; 21(6):514-20. PubMed ID: 671447 [No Abstract] [Full Text] [Related]
5. Comparison of the properties of metabolites of CCNU. Wheeler GP; Johnston TP; Bowdon BJ; McCaleb GS; Hill DL; Montgomery JA Biochem Pharmacol; 1977 Dec; 26(24):2331-6. PubMed ID: 145865 [No Abstract] [Full Text] [Related]
6. Mechanism of uptake of nitrosoureas by L5178Y lymphoblasts in vitro. Begleiter A; Lam HP; Goldenberg GJ Cancer Res; 1977 Apr; 37(4):1022-7. PubMed ID: 557367 [TBL] [Abstract][Full Text] [Related]
7. Alkylation and carbamoylation intermediates from the carcinostatic 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU)-1. Reed DJ; May HE Life Sci; 1975 Apr; 16(8):1263-70. PubMed ID: 1134193 [No Abstract] [Full Text] [Related]
8. Hydroxylation of the carcinostatic 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) by rat liver microsomes. May HE; Boose R; Reed DJ Biochem Biophys Res Commun; 1974 Mar; 57(2):426-33. PubMed ID: 4151402 [No Abstract] [Full Text] [Related]
9. Mechanism of action of the nitrosoureas--IV. Reactions of bis-chloroethyl nitrosourea and chloroethyl cyclohexyl nitrosourea with deoxyribonucleic acid. Gombar CT; Tong WP; Ludlum DB Biochem Pharmacol; 1980 Oct; 29(19):2639-43. PubMed ID: 7191706 [No Abstract] [Full Text] [Related]
10. Denitrosation of carcinostatic nitrosoureas by purified NADPH cytochrome P-450 reductase and rat liver microsomes to yield nitric oxide under anaerobic conditions. Potter DW; Reed DJ Arch Biochem Biophys; 1982 Jun; 216(1):158-69. PubMed ID: 6808923 [No Abstract] [Full Text] [Related]
11. Active site specific inactivation of chymotrypsin by cyclohexyl isocyanate formed during degradation of the carcinostatic 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea. Babson JR; Reed DJ; Sinkey MA Biochemistry; 1977 Apr; 16(8):1584-9. PubMed ID: 856251 [TBL] [Abstract][Full Text] [Related]
12. Synthesis and identification of products derived from the metabolism of the carcinostatic 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea by rat liver microsomes. May HE; Kohlhepp SJ; Boose RB; Reed DJ Cancer Res; 1979 Mar; 39(3):762-72. PubMed ID: 427763 [TBL] [Abstract][Full Text] [Related]
13. Binding of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea to L1210 cell nuclear proteins. Woolley PV; Dion RL; Kohn KW; Bono VH Cancer Res; 1976 Apr; 36(4):1470-4. PubMed ID: 4221 [TBL] [Abstract][Full Text] [Related]
14. Prolonged depression of hepatic microsomal drug metabolism and hemoprotein levels following a single dose of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU). Litterst CL Biochem Pharmacol; 1981 May; 30(9):1014-6. PubMed ID: 7236311 [No Abstract] [Full Text] [Related]
15. Metabolism of 1,3-bis(2-chloroethyl)-1-nitrosourea by rat hepatic microsomes. Lin HS; Weinkam RJ J Med Chem; 1981 Jun; 24(6):761-3. PubMed ID: 7252986 [TBL] [Abstract][Full Text] [Related]
16. The binding of 14C labelled 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) to macromolecules of sensitive and resistant tumours. Connors TA; Hare JR Br J Cancer; 1974 Nov; 30(5):477-80. PubMed ID: 4469198 [No Abstract] [Full Text] [Related]
17. Binding of chlorozotocin and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea to chromatin and nucleosomal fractions of HeLa cells. Tew KD; Sudhakar S; Schein PS; Smulson ME Cancer Res; 1978 Oct; 38(10):3371-8. PubMed ID: 150941 [No Abstract] [Full Text] [Related]
18. Fluorinated analogues of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea: an attempt to control metabolism. Foster AB; Jarman M; Coe PL; Sleigh J; Tatlow JC J Med Chem; 1980 Nov; 23(11):1226-9. PubMed ID: 7452672 [TBL] [Abstract][Full Text] [Related]
19. Pharmacology of the nitrosoureas: an overview. Oliverio VT Cancer Treat Rep; 1976 Jun; 60(6):703-7. PubMed ID: 821608 [No Abstract] [Full Text] [Related]
20. Biodistribution of 14C-lomustine in an animal tumor model. Castronovo FP; Potsaid MS; Kopiwoda SY J Pharm Sci; 1980 Jan; 69(1):87-9. PubMed ID: 7354451 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]