BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

128 related articles for article (PubMed ID: 12127072)

  • 1. Determinants within the C-terminus of the human norepinephrine transporter dictate transporter trafficking, stability, and activity.
    Bauman PA; Blakely RD
    Arch Biochem Biophys; 2002 Aug; 404(1):80-91. PubMed ID: 12127072
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Functional importance of the C-terminus of the human norepinephrine transporter.
    Distelmaier F; Wiedemann P; Brüss M; Bönisch H
    J Neurochem; 2004 Nov; 91(3):537-46. PubMed ID: 15485485
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inability to N-glycosylate the human norepinephrine transporter reduces protein stability, surface trafficking, and transport activity but not ligand recognition.
    Melikian HE; Ramamoorthy S; Tate CG; Blakely RD
    Mol Pharmacol; 1996 Aug; 50(2):266-76. PubMed ID: 8700133
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A mutation in the human norepinephrine transporter gene (SLC6A2) associated with orthostatic intolerance disrupts surface expression of mutant and wild-type transporters.
    Hahn MK; Robertson D; Blakely RD
    J Neurosci; 2003 Jun; 23(11):4470-8. PubMed ID: 12805287
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human norepinephrine transporter. Biosynthetic studies using a site-directed polyclonal antibody.
    Melikian HE; McDonald JK; Gu H; Rudnick G; Moore KR; Blakely RD
    J Biol Chem; 1994 Apr; 269(16):12290-7. PubMed ID: 8163533
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The N-terminus of the norepinephrine transporter regulates the magnitude and selectivity of the transporter-associated leak current.
    Binda F; Lute BJ; Dipace C; Blakely RD; Galli A
    Neuropharmacology; 2006 Mar; 50(3):354-61. PubMed ID: 16289633
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Functional consequences of homo- but not hetero-oligomerization between transporters for the biogenic amine neurotransmitters.
    Kocabas AM; Rudnick G; Kilic F
    J Neurochem; 2003 Jun; 85(6):1513-20. PubMed ID: 12787070
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pharmacological properties of the naturally occurring Ala(457)Pro variant of the human norepinephrine transporter.
    Paczkowski FA; Bönisch H; Bryan-Lluka LJ
    Pharmacogenetics; 2002 Mar; 12(2):165-73. PubMed ID: 11875370
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Amino acids involved in differences in the pharmacological profiles of the rat and human noradrenaline transporters.
    Paczkowski FA; Bryan-Lluka LJ
    Naunyn Schmiedebergs Arch Pharmacol; 2002 Apr; 365(4):312-7. PubMed ID: 11919656
    [TBL] [Abstract][Full Text] [Related]  

  • 10. chi-Conopeptide MrIA partially overlaps desipramine and cocaine binding sites on the human norepinephrine transporter.
    Bryan-Lluka LJ; Bönisch H; Lewis RJ
    J Biol Chem; 2003 Oct; 278(41):40324-9. PubMed ID: 12837768
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Increased MIBG uptake after transfer of the human norepinephrine transporter gene in rat hepatoma.
    Altmann A; Kissel M; Zitzmann S; Kübler W; Mahmut M; Peschke P; Haberkorn U
    J Nucl Med; 2003 Jun; 44(6):973-80. PubMed ID: 12791828
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An E-box motif residing in the exon/intron 1 junction regulates both transcriptional activation and splicing of the human norepinephrine transporter gene.
    Kim CH; Ardayfio P; Kim KS
    J Biol Chem; 2001 Jul; 276(27):24797-805. PubMed ID: 11333263
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Functional characterization of the splicing variants of human norepinephrine transporter.
    Kitayama S; Morita K; Dohi T
    Neurosci Lett; 2001 Oct; 312(2):108-12. PubMed ID: 11595346
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Roles of transmembrane domain 2 and the first intracellular loop in human noradrenaline transporter function: pharmacological and SCAM analysis.
    Sucic S; Bryan-Lluka LJ
    J Neurochem; 2005 Sep; 94(6):1620-30. PubMed ID: 16092934
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pharmacological properties of naturally occurring variants of the human norepinephrine transporter.
    Runkel F; Brüss M; Nöthen MM; Stöber G; Propping P; Bönisch H
    Pharmacogenetics; 2000 Jul; 10(5):397-405. PubMed ID: 10898109
    [TBL] [Abstract][Full Text] [Related]  

  • 16. C-terminal region regulates the functional expression of human noradrenaline transporter splice variants.
    Sogawa C; Kumagai K; Sogawa N; Morita K; Dohi T; Kitayama S
    Biochem J; 2007 Jan; 401(1):185-95. PubMed ID: 16965261
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A previously undescribed intron and extensive 5' upstream sequence, but not Phox2a-mediated transactivation, are necessary for high level cell type-specific expression of the human norepinephrine transporter gene.
    Kim CH; Kim HS; Cubells JF; Kim KS
    J Biol Chem; 1999 Mar; 274(10):6507-18. PubMed ID: 10037744
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A proximal promoter domain containing a homeodomain-binding core motif interacts with multiple transcription factors, including HoxA5 and Phox2 proteins, and critically regulates cell type-specific transcription of the human norepinephrine transporter gene.
    Kim CH; Hwang DY; Park JJ; Kim KS
    J Neurosci; 2002 Apr; 22(7):2579-89. PubMed ID: 11923423
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Amphetamine induces a calcium/calmodulin-dependent protein kinase II-dependent reduction in norepinephrine transporter surface expression linked to changes in syntaxin 1A/transporter complexes.
    Dipace C; Sung U; Binda F; Blakely RD; Galli A
    Mol Pharmacol; 2007 Jan; 71(1):230-9. PubMed ID: 17032905
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Single nucleotide polymorphisms in the human norepinephrine transporter gene affect expression, trafficking, antidepressant interaction, and protein kinase C regulation.
    Hahn MK; Mazei-Robison MS; Blakely RD
    Mol Pharmacol; 2005 Aug; 68(2):457-66. PubMed ID: 15894713
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.