BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

174 related articles for article (PubMed ID: 12130690)

  • 1. Modulation of mouse and human phenobarbital-responsive enhancer module by nuclear receptors.
    Mäkinen J; Frank C; Jyrkkärinne J; Gynther J; Carlberg C; Honkakoski P
    Mol Pharmacol; 2002 Aug; 62(2):366-78. PubMed ID: 12130690
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression.
    Wang H; Faucette S; Sueyoshi T; Moore R; Ferguson S; Negishi M; LeCluyse EL
    J Biol Chem; 2003 Apr; 278(16):14146-52. PubMed ID: 12571232
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene.
    Sueyoshi T; Kawamoto T; Zelko I; Honkakoski P; Negishi M
    J Biol Chem; 1999 Mar; 274(10):6043-6. PubMed ID: 10037683
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor.
    Faucette SR; Sueyoshi T; Smith CM; Negishi M; Lecluyse EL; Wang H
    J Pharmacol Exp Ther; 2006 Jun; 317(3):1200-9. PubMed ID: 16513849
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene.
    Kawamoto T; Sueyoshi T; Zelko I; Moore R; Washburn K; Negishi M
    Mol Cell Biol; 1999 Sep; 19(9):6318-22. PubMed ID: 10454578
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene.
    Honkakoski P; Zelko I; Sueyoshi T; Negishi M
    Mol Cell Biol; 1998 Oct; 18(10):5652-8. PubMed ID: 9742082
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cell Cycle and Apoptosis Regulator 1, CCAR1, Regulates Enhancer-Dependent Nuclear Receptor CAR Transactivation.
    Kanno Y; Zhao S; Yamashita N; Saito N; Ujiie A; Iijima R; Kikawa N; Nemoto K; Inouye Y
    Mol Pharmacol; 2019 Jan; 95(1):120-126. PubMed ID: 30397001
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Glucocorticoid receptor enhancement of pregnane X receptor-mediated CYP2B6 regulation in primary human hepatocytes.
    Wang H; Faucette SR; Gilbert D; Jolley SL; Sueyoshi T; Negishi M; LeCluyse EL
    Drug Metab Dispos; 2003 May; 31(5):620-30. PubMed ID: 12695351
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The induction of human UDP-glucuronosyltransferase 1A1 mediated through a distal enhancer module by flavonoids and xenobiotics.
    Sugatani J; Yamakawa K; Tonda E; Nishitani S; Yoshinari K; Degawa M; Abe I; Noguchi H; Miwa M
    Biochem Pharmacol; 2004 Mar; 67(5):989-1000. PubMed ID: 15104253
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human constitutive androstane receptor mediates induction of CYP2B6 gene expression by phenytoin.
    Wang H; Faucette S; Moore R; Sueyoshi T; Negishi M; LeCluyse E
    J Biol Chem; 2004 Jul; 279(28):29295-301. PubMed ID: 15123723
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dexamethasone enhances constitutive androstane receptor expression in human hepatocytes: consequences on cytochrome P450 gene regulation.
    Pascussi JM; Gerbal-Chaloin S; Fabre JM; Maurel P; Vilarem MJ
    Mol Pharmacol; 2000 Dec; 58(6):1441-50. PubMed ID: 11093784
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel CAR-mediated mechanism for synergistic activation of two distinct elements within the human cytochrome P450 2B6 gene in HepG2 cells.
    Swales K; Kakizaki S; Yamamoto Y; Inoue K; Kobayashi K; Negishi M
    J Biol Chem; 2005 Feb; 280(5):3458-66. PubMed ID: 15563456
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of the human CYP2B6 gene by the nuclear pregnane X receptor.
    Goodwin B; Moore LB; Stoltz CM; McKee DD; Kliewer SA
    Mol Pharmacol; 2001 Sep; 60(3):427-31. PubMed ID: 11502872
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR.
    Xie W; Barwick JL; Simon CM; Pierce AM; Safe S; Blumberg B; Guzelian PS; Evans RM
    Genes Dev; 2000 Dec; 14(23):3014-23. PubMed ID: 11114890
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutational analysis of the CYP2B2 phenobarbital response unit and inhibitory effect of the constitutive androstane receptor on phenobarbital responsiveness.
    Paquet Y; Trottier E; Beaudet MJ; Anderson A
    J Biol Chem; 2000 Dec; 275(49):38427-36. PubMed ID: 10993889
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phenobarbital response elements of cytochrome P450 genes and nuclear receptors.
    Sueyoshi T; Negishi M
    Annu Rev Pharmacol Toxicol; 2001; 41():123-43. PubMed ID: 11264453
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cohesin protein SMC1 represses the nuclear receptor CAR-mediated synergistic activation of a human P450 gene by xenobiotics.
    Inoue K; Borchers CH; Negishi M
    Biochem J; 2006 Aug; 398(1):125-33. PubMed ID: 16623664
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
    Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
    Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transcriptional regulation of cytochrome p450 2B genes by nuclear receptors.
    Wang H; Negishi M
    Curr Drug Metab; 2003 Dec; 4(6):515-25. PubMed ID: 14683479
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers.
    Faucette SR; Zhang TC; Moore R; Sueyoshi T; Omiecinski CJ; LeCluyse EL; Negishi M; Wang H
    J Pharmacol Exp Ther; 2007 Jan; 320(1):72-80. PubMed ID: 17041008
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.