BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

192 related articles for article (PubMed ID: 12134946)

  • 21. Characterization of the regional intestinal kinetics of drug efflux in rat and human intestine and in Caco-2 cells.
    Makhey VD; Guo A; Norris DA; Hu P; Yan J; Sinko PJ
    Pharm Res; 1998 Aug; 15(8):1160-7. PubMed ID: 9706044
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Delineation of human peptide transporter 1 (hPepT1)-mediated uptake and transport of substrates with varying transporter affinities utilizing stably transfected hPepT1/Madin-Darby canine kidney clones and Caco-2 cells.
    Bhardwaj RK; Herrera-Ruiz D; Sinko PJ; Gudmundsson OS; Knipp G
    J Pharmacol Exp Ther; 2005 Sep; 314(3):1093-100. PubMed ID: 15901802
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Peptide transporter substrate identification during permeability screening in drug discovery: comparison of transfected MDCK-hPepT1 cells to Caco-2 cells.
    Balimane PV; Chong S; Patel K; Quan Y; Timoszyk J; Han YH; Wang B; Vig B; Faria TN
    Arch Pharm Res; 2007 Apr; 30(4):507-18. PubMed ID: 17489369
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Effects of grapefruit juice and orange juice components on P-glycoprotein- and MRP2-mediated drug efflux.
    Honda Y; Ushigome F; Koyabu N; Morimoto S; Shoyama Y; Uchiumi T; Kuwano M; Ohtani H; Sawada Y
    Br J Pharmacol; 2004 Dec; 143(7):856-64. PubMed ID: 15504753
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Evaluation of P-glycoprotein-mediated renal drug interactions in an MDR1-MDCK model.
    Karyekar CS; Eddington ND; Garimella TS; Gubbins PO; Dowling TC
    Pharmacotherapy; 2003 Apr; 23(4):436-42. PubMed ID: 12680473
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Comparison of furosemide and vinblastine secretion from cell lines overexpressing multidrug resistance protein (P-glycoprotein) and multidrug resistance-associated proteins (MRP1 and MRP2).
    Flanagan SD; Cummins CL; Susanto M; Liu X; Takahashi LH; Benet LZ
    Pharmacology; 2002; 64(3):126-34. PubMed ID: 11834888
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Vectorial transport of the plant alkaloid berberine by double-transfected cells expressing the human organic cation transporter 1 (OCT1, SLC22A1) and the efflux pump MDR1 P-glycoprotein (ABCB1).
    Nies AT; Herrmann E; Brom M; Keppler D
    Naunyn Schmiedebergs Arch Pharmacol; 2008 Feb; 376(6):449-61. PubMed ID: 18157518
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Bidirectional transport of rhodamine 123 and Hoechst 33342, fluorescence probes of the binding sites on P-glycoprotein, across MDCK-MDR1 cell monolayers.
    Tang F; Ouyang H; Yang JZ; Borchardt RT
    J Pharm Sci; 2004 May; 93(5):1185-94. PubMed ID: 15067695
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Both P-gp and MRP2 mediate transport of Lopinavir, a protease inhibitor.
    Agarwal S; Pal D; Mitra AK
    Int J Pharm; 2007 Jul; 339(1-2):139-47. PubMed ID: 17451894
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Breast cancer resistance protein (Bcrp1/Abcg2) limits net intestinal uptake of quercetin in rats by facilitating apical efflux of glucuronides.
    Sesink AL; Arts IC; de Boer VC; Breedveld P; Schellens JH; Hollman PC; Russel FG
    Mol Pharmacol; 2005 Jun; 67(6):1999-2006. PubMed ID: 15749994
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Mechanisms and interaction of vinblastine and reduced glutathione transport in membrane vesicles by the rabbit multidrug resistance protein Mrp2 expressed in insect cells.
    Van Aubel RA; Koenderink JB; Peters JG; Van Os CH; Russel FG
    Mol Pharmacol; 1999 Oct; 56(4):714-9. PubMed ID: 10496953
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Characterizing the expression of CYP3A4 and efflux transporters (P-gp, MRP1, and MRP2) in CYP3A4-transfected Caco-2 cells after induction with sodium butyrate and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate.
    Cummins CL; Mangravite LM; Benet LZ
    Pharm Res; 2001 Aug; 18(8):1102-9. PubMed ID: 11587480
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Ezrin regulates the expression of Mrp2/Abcc2 and Mdr1/Abcb1 along the rat small intestinal tract.
    Nakano T; Sekine S; Ito K; Horie T
    Am J Physiol Gastrointest Liver Physiol; 2013 Dec; 305(11):G807-17. PubMed ID: 24091598
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Functional characterization of sodium-dependent multivitamin transporter in MDCK-MDR1 cells and its utilization as a target for drug delivery.
    Luo S; Kansara VS; Zhu X; Mandava NK; Pal D; Mitra AK
    Mol Pharm; 2006; 3(3):329-39. PubMed ID: 16749865
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Evidence for a non-MDR1 component in digoxin secretion by human intestinal Caco-2 epithelial layers.
    Lowes S; Cavet ME; Simmons NL
    Eur J Pharmacol; 2003 Jan; 458(1-2):49-56. PubMed ID: 12498906
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Avermectin transepithelial transport in MDR1- and MRP-transfected canine kidney monolayers.
    Brayden DJ; Griffin J
    Vet Res Commun; 2008 Jan; 32(1):93-106. PubMed ID: 17578674
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Multiple pathways for fluoroquinolone secretion by human intestinal epithelial (Caco-2) cells.
    Lowes S; Simmons NL
    Br J Pharmacol; 2002 Mar; 135(5):1263-75. PubMed ID: 11877335
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Correlation of gene expression of ten drug efflux proteins of the ATP-binding cassette transporter family in normal human jejunum and in human intestinal epithelial Caco-2 cell monolayers.
    Taipalensuu J; Törnblom H; Lindberg G; Einarsson C; Sjöqvist F; Melhus H; Garberg P; Sjöström B; Lundgren B; Artursson P
    J Pharmacol Exp Ther; 2001 Oct; 299(1):164-70. PubMed ID: 11561076
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Retroviral transfection of Madin-Darby canine kidney cells with human MDR1 results in a major increase in globotriaosylceramide and 10(5)- to 10(6)-fold increased cell sensitivity to verocytotoxin. Role of p-glycoprotein in glycolipid synthesis.
    Lala P; Ito S; Lingwood CA
    J Biol Chem; 2000 Mar; 275(9):6246-51. PubMed ID: 10692420
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Upregulation of the expression of endogenous Mdr1 P-glycoprotein enhances lipid translocation in MDCK cells transfected with human MRP2.
    Raggers RJ; Vogels I; van Meer G
    Histochem Cell Biol; 2002 Feb; 117(2):181-5. PubMed ID: 11935294
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.