319 related articles for article (PubMed ID: 12140282)
1. Expression of human telomerase (hTERT) does not prevent stress-induced senescence in normal human fibroblasts but protects the cells from stress-induced apoptosis and necrosis.
Gorbunova V; Seluanov A; Pereira-Smith OM
J Biol Chem; 2002 Oct; 277(41):38540-9. PubMed ID: 12140282
[TBL] [Abstract][Full Text] [Related]
2. Stress-induced premature senescence in BJ and hTERT-BJ1 human foreskin fibroblasts.
de Magalhães JP; Chainiaux F; Remacle J; Toussaint O
FEBS Lett; 2002 Jul; 523(1-3):157-62. PubMed ID: 12123824
[TBL] [Abstract][Full Text] [Related]
3. Stress-induced premature senescence in hTERT-expressing ataxia telangiectasia fibroblasts.
Naka K; Tachibana A; Ikeda K; Motoyama N
J Biol Chem; 2004 Jan; 279(3):2030-7. PubMed ID: 14570874
[TBL] [Abstract][Full Text] [Related]
4. Gene expression and regulation in H2O2-induced premature senescence of human foreskin fibroblasts expressing or not telomerase.
de Magalhães JP; Chainiaux F; de Longueville F; Mainfroid V; Migeot V; Marcq L; Remacle J; Salmon M; Toussaint O
Exp Gerontol; 2004 Sep; 39(9):1379-89. PubMed ID: 15489061
[TBL] [Abstract][Full Text] [Related]
5. Normal human fibroblasts are resistant to RAS-induced senescence.
Benanti JA; Galloway DA
Mol Cell Biol; 2004 Apr; 24(7):2842-52. PubMed ID: 15024073
[TBL] [Abstract][Full Text] [Related]
6. Telomerase prevents accelerated senescence in glucose-6-phosphate dehydrogenase (G6PD)-deficient human fibroblasts.
Wu YH; Cheng ML; Ho HY; Chiu DT; Wang TC
J Biomed Sci; 2009 Feb; 16(1):18. PubMed ID: 19272180
[TBL] [Abstract][Full Text] [Related]
7. Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1.
Itahana K; Zou Y; Itahana Y; Martinez JL; Beausejour C; Jacobs JJ; Van Lohuizen M; Band V; Campisi J; Dimri GP
Mol Cell Biol; 2003 Jan; 23(1):389-401. PubMed ID: 12482990
[TBL] [Abstract][Full Text] [Related]
8. Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics.
Dickson MA; Hahn WC; Ino Y; Ronfard V; Wu JY; Weinberg RA; Louis DN; Li FP; Rheinwald JG
Mol Cell Biol; 2000 Feb; 20(4):1436-47. PubMed ID: 10648628
[TBL] [Abstract][Full Text] [Related]
9. Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes.
Toussaint O; Medrano EE; von Zglinicki T
Exp Gerontol; 2000 Oct; 35(8):927-45. PubMed ID: 11121681
[TBL] [Abstract][Full Text] [Related]
10. p53-Dependent accelerated senescence induced by ionizing radiation in breast tumour cells.
Jones KR; Elmore LW; Jackson-Cook C; Demasters G; Povirk LF; Holt SE; Gewirtz DA
Int J Radiat Biol; 2005 Jun; 81(6):445-58. PubMed ID: 16308915
[TBL] [Abstract][Full Text] [Related]
11. Irreversible cellular senescence induced by prolonged exposure to H2O2 involves DNA-damage-and-repair genes and telomere shortening.
Duan J; Duan J; Zhang Z; Tong T
Int J Biochem Cell Biol; 2005 Jul; 37(7):1407-20. PubMed ID: 15833273
[TBL] [Abstract][Full Text] [Related]
12. Inactivation of p16INK4a, with retention of pRB and p53/p21cip1 function, in human MRC5 fibroblasts that overcome a telomere-independent crisis during immortalization.
Taylor LM; James A; Schuller CE; Brce J; Lock RB; Mackenzie KL
J Biol Chem; 2004 Oct; 279(42):43634-45. PubMed ID: 15308640
[TBL] [Abstract][Full Text] [Related]
13. Evidence that high telomerase activity may induce a senescent-like growth arrest in human fibroblasts.
Gorbunova V; Seluanov A; Pereira-Smith OM
J Biol Chem; 2003 Feb; 278(9):7692-8. PubMed ID: 12496279
[TBL] [Abstract][Full Text] [Related]
14. Measurements of hydrogen peroxide induced premature senescence: senescence-associated beta-galactosidase and DNA synthesis index in human diploid fibroblasts with down-regulated p53 or Rb.
Chen QM; Tu VC; Liu J
Biogerontology; 2000; 1(4):335-9. PubMed ID: 11708215
[TBL] [Abstract][Full Text] [Related]
15. Absence of cancer-associated changes in human fibroblasts immortalized with telomerase.
Morales CP; Holt SE; Ouellette M; Kaur KJ; Yan Y; Wilson KS; White MA; Wright WE; Shay JW
Nat Genet; 1999 Jan; 21(1):115-8. PubMed ID: 9916803
[TBL] [Abstract][Full Text] [Related]
16. Telomere-based proliferative lifespan barriers in Werner-syndrome fibroblasts involve both p53-dependent and p53-independent mechanisms.
Davis T; Singhrao SK; Wyllie FS; Haughton MF; Smith PJ; Wiltshire M; Wynford-Thomas D; Jones CJ; Faragher RG; Kipling D
J Cell Sci; 2003 Apr; 116(Pt 7):1349-57. PubMed ID: 12615976
[TBL] [Abstract][Full Text] [Related]
17. A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status.
Rheinwald JG; Hahn WC; Ramsey MR; Wu JY; Guo Z; Tsao H; De Luca M; Catricalà C; O'Toole KM
Mol Cell Biol; 2002 Jul; 22(14):5157-72. PubMed ID: 12077343
[TBL] [Abstract][Full Text] [Related]
18. Knocking down p53 with siRNA does not affect the overexpression of p21WAF-1 after exposure of IMR-90 hTERT fibroblasts to a sublethal concentration of H2O2 leading to premature senescence.
Zdanov S; Debacq-Chainiaux F; Toussaint O
Ann N Y Acad Sci; 2007 Apr; 1100():316-22. PubMed ID: 17460194
[TBL] [Abstract][Full Text] [Related]
19. A human TERT C-terminal polypeptide sensitizes HeLa cells to H2O2-induced senescence without affecting telomerase enzymatic activity.
Huang J; Bai YX; Han SW; Ng SS; Jing DD; Wong BC; Huang CF; Kung HF; Lin MC
Biochem Biophys Res Commun; 2003 Feb; 301(3):627-32. PubMed ID: 12565825
[TBL] [Abstract][Full Text] [Related]
20. Homocysteine accelerates senescence of endothelial cells via DNA hypomethylation of human telomerase reverse transcriptase.
Zhang D; Sun X; Liu J; Xie X; Cui W; Zhu Y
Arterioscler Thromb Vasc Biol; 2015 Jan; 35(1):71-8. PubMed ID: 25359865
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
