BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 12142565)

  • 1. Involvement of superoxide in excitotoxicity and DNA fragmentation in striatal vulnerability in mice after treatment with the mitochondrial toxin, 3-nitropropionic acid.
    Kim GW; Chan PH
    J Cereb Blood Flow Metab; 2002 Jul; 22(7):798-809. PubMed ID: 12142565
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP.
    Andreassen OA; Ferrante RJ; Dedeoglu A; Albers DW; Klivenyi P; Carlson EJ; Epstein CJ; Beal MF
    Exp Neurol; 2001 Jan; 167(1):189-95. PubMed ID: 11161607
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Excitotoxicity is required for induction of oxidative stress and apoptosis in mouse striatum by the mitochondrial toxin, 3-nitropropionic acid.
    Kim GW; Copin JC; Kawase M; Chen SF; Sato S; Gobbel GT; Chan PH
    J Cereb Blood Flow Metab; 2000 Jan; 20(1):119-29. PubMed ID: 10616800
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Oxidative stress and neuronal DNA fragmentation mediate age-dependent vulnerability to the mitochondrial toxin, 3-nitropropionic acid, in the mouse striatum.
    Kim GW; Chan PH
    Neurobiol Dis; 2001 Feb; 8(1):114-26. PubMed ID: 11162245
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Striatal dopamine level contributes to hydroxyl radical generation and subsequent neurodegeneration in the striatum in 3-nitropropionic acid-induced Huntington's disease in rats.
    Pandey M; Borah A; Varghese M; Barman PK; Mohanakumar KP; Usha R
    Neurochem Int; 2009 Nov; 55(6):431-7. PubMed ID: 19410615
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metabolic compromise with systemic 3-nitropropionic acid produces striatal apoptosis in Sprague-Dawley rats but not in BALB/c ByJ mice.
    Alexi T; Hughes PE; Knüsel B; Tobin AJ
    Exp Neurol; 1998 Sep; 153(1):74-93. PubMed ID: 9743569
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging.
    Van Remmen H; Ikeno Y; Hamilton M; Pahlavani M; Wolf N; Thorpe SR; Alderson NL; Baynes JW; Epstein CJ; Huang TT; Nelson J; Strong R; Richardson A
    Physiol Genomics; 2003 Dec; 16(1):29-37. PubMed ID: 14679299
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oxidative cellular damage and the reduction of APE/Ref-1 expression after experimental traumatic brain injury.
    Lewén A; Sugawara T; Gasche Y; Fujimura M; Chan PH
    Neurobiol Dis; 2001 Jun; 8(3):380-90. PubMed ID: 11447995
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Protective role of sertraline against 3-nitropropionic acid-induced cognitive dysfunction and redox ratio in striatum, cortex and hippocampus of rat brain.
    Kumar P; Kumar A
    Indian J Exp Biol; 2009 Sep; 47(9):715-22. PubMed ID: 19957883
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Paradoxical increase in 3-nitropropionic acid neurotoxicity by alpha-phenyl-tert-butyl-nitrone, a spin-trapping agent.
    Lan MY; Chang YY; Chen SS; Wu HS; Chen WH; Liu JS
    Chang Gung Med J; 2005 Feb; 28(2):77-84. PubMed ID: 15880982
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Excitotoxic brain damage involves early peroxynitrite formation in a model of Huntington's disease in rats: protective role of iron porphyrinate 5,10,15,20-tetrakis (4-sulfonatophenyl)porphyrinate iron (III).
    Pérez-De La Cruz V; González-Cortés C; Galván-Arzate S; Medina-Campos ON; Pérez-Severiano F; Ali SF; Pedraza-Chaverrí J; Santamaría A
    Neuroscience; 2005; 135(2):463-74. PubMed ID: 16111817
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Neuroprotective effect of taurine in 3-nitropropionic acid-induced experimental animal model of Huntington's disease phenotype.
    Tadros MG; Khalifa AE; Abdel-Naim AB; Arafa HM
    Pharmacol Biochem Behav; 2005 Nov; 82(3):574-82. PubMed ID: 16337998
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Neuropathological and behavioral changes induced by various treatment paradigms with MPTP and 3-nitropropionic acid in mice: towards a model of striatonigral degeneration (multiple system atrophy).
    Stefanova N; Puschban Z; Fernagut PO; Brouillet E; Tison F; Reindl M; Jellinger KA; Poewe W; Wenning GK
    Acta Neuropathol; 2003 Aug; 106(2):157-66. PubMed ID: 12764627
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Conditional knockout of Mn superoxide dismutase in postnatal motor neurons reveals resistance to mitochondrial generated superoxide radicals.
    Misawa H; Nakata K; Matsuura J; Moriwaki Y; Kawashima K; Shimizu T; Shirasawa T; Takahashi R
    Neurobiol Dis; 2006 Jul; 23(1):169-77. PubMed ID: 16677818
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutant SOD1G93A in bone marrow-derived cells exacerbates 3-nitropropionic acid induced striatal damage in mice.
    Huang QY; Yu L; Ferrante RJ; Chen JF
    Neurosci Lett; 2007 May; 418(2):175-80. PubMed ID: 17418947
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cytochrome c oxidase isoform IV-2 is involved in 3-nitropropionic acid-induced toxicity in striatal astrocytes.
    Singh S; Misiak M; Beyer C; Arnold S
    Glia; 2009 Nov; 57(14):1480-91. PubMed ID: 19306371
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Creatine protects against 3-nitropropionic acid-induced cell death in murine corticostriatal slice cultures.
    Vis JC; de Boer-Van Huizen RT; Verbeek MM; de Waal RM; ten Donkelaar HJ; Kremer B
    Brain Res; 2004 Oct; 1024(1-2):16-24. PubMed ID: 15451363
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Superoxide-mediated cytotoxicity in superoxide dismutase-deficient fetal fibroblasts.
    Huang TT; Yasunami M; Carlson EJ; Gillespie AM; Reaume AG; Hoffman EK; Chan PH; Scott RW; Epstein CJ
    Arch Biochem Biophys; 1997 Aug; 344(2):424-32. PubMed ID: 9264557
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Whole body hyperthermia reduces oxidative stress in the striatum of rats in an animal model of mitochondrial toxicity with 3-nitropropionic acid.
    Medina-Navarro R; Guerrero-Linares I
    Int J Hyperthermia; 2009 Jun; 25(4):280-8. PubMed ID: 19440936
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Alterations in mitochondrial function, hydrogen peroxide release and oxidative damage in mouse hind-limb skeletal muscle during aging.
    Mansouri A; Muller FL; Liu Y; Ng R; Faulkner J; Hamilton M; Richardson A; Huang TT; Epstein CJ; Van Remmen H
    Mech Ageing Dev; 2006 Mar; 127(3):298-306. PubMed ID: 16405961
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.