BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

234 related articles for article (PubMed ID: 12145149)

  • 1. Association of SH2-containing inositol phosphatase 2 with the insulin resistance of diabetic db/db mice.
    Hori H; Sasaoka T; Ishihara H; Wada T; Murakami S; Ishiki M; Kobayashi M
    Diabetes; 2002 Aug; 51(8):2387-94. PubMed ID: 12145149
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Decreased Akt kinase activity and insulin resistance in C57BL/KsJ-Leprdb/db mice.
    Shao J; Yamashita H; Qiao L; Friedman JE
    J Endocrinol; 2000 Oct; 167(1):107-15. PubMed ID: 11018758
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5'-phosphatase catalytic activity.
    Wada T; Sasaoka T; Funaki M; Hori H; Murakami S; Ishiki M; Haruta T; Asano T; Ogawa W; Ishihara H; Kobayashi M
    Mol Cell Biol; 2001 Mar; 21(5):1633-46. PubMed ID: 11238900
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation of protein kinase C-zeta by insulin and phosphatidylinositol-3,4,5-(PO4)3 is defective in muscle in type 2 diabetes and impaired glucose tolerance: amelioration by rosiglitazone and exercise.
    Beeson M; Sajan MP; Dizon M; Grebenev D; Gomez-Daspet J; Miura A; Kanoh Y; Powe J; Bandyopadhyay G; Standaert ML; Farese RV
    Diabetes; 2003 Aug; 52(8):1926-34. PubMed ID: 12882907
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rosiglitazone, insulin treatment, and fasting correct defective activation of protein kinase C-zeta/lambda by insulin in vastus lateralis muscles and adipocytes of diabetic rats.
    Kanoh Y; Bandyopadhyay G; Sajan MP; Standaert ML; Farese RV
    Endocrinology; 2001 Apr; 142(4):1595-605. PubMed ID: 11250941
    [TBL] [Abstract][Full Text] [Related]  

  • 6. SH2-containing inositol phosphatase 2 negatively regulates insulin-induced glycogen synthesis in L6 myotubes.
    Sasaoka T; Hori H; Wada T; Ishiki M; Haruta T; Ishihara H; Kobayashi M
    Diabetologia; 2001 Oct; 44(10):1258-67. PubMed ID: 11692174
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Defective insulin-induced GLUT4 translocation in skeletal muscle of high fat-fed rats is associated with alterations in both Akt/protein kinase B and atypical protein kinase C (zeta/lambda) activities.
    Tremblay F; Lavigne C; Jacques H; Marette A
    Diabetes; 2001 Aug; 50(8):1901-10. PubMed ID: 11473054
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Insulin-stimulated plasma membrane association and activation of Akt2, aPKC zeta and aPKC lambda in high fat fed rodent skeletal muscle.
    Herr HJ; Bernard JR; Reeder DW; Rivas DA; Limon JJ; Yaspelkis BB
    J Physiol; 2005 Jun; 565(Pt 2):627-36. PubMed ID: 15802290
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Increased p85/55/50 expression and decreased phosphotidylinositol 3-kinase activity in insulin-resistant human skeletal muscle.
    Bandyopadhyay GK; Yu JG; Ofrecio J; Olefsky JM
    Diabetes; 2005 Aug; 54(8):2351-9. PubMed ID: 16046301
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Skeletal muscle insulin resistance in obesity-associated type 2 diabetes in monkeys is linked to a defect in insulin activation of protein kinase C-zeta/lambda/iota.
    Standaert ML; Ortmeyer HK; Sajan MP; Kanoh Y; Bandyopadhyay G; Hansen BC; Farese RV
    Diabetes; 2002 Oct; 51(10):2936-43. PubMed ID: 12351430
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lipid phosphatases as a possible therapeutic target in cases of type 2 diabetes and obesity.
    Sasaoka T; Wada T; Tsuneki H
    Pharmacol Ther; 2006 Dec; 112(3):799-809. PubMed ID: 16842857
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evidence that SHIP-1 contributes to phosphatidylinositol 3,4,5-trisphosphate metabolism in T lymphocytes and can regulate novel phosphoinositide 3-kinase effectors.
    Freeburn RW; Wright KL; Burgess SJ; Astoul E; Cantrell DA; Ward SG
    J Immunol; 2002 Nov; 169(10):5441-50. PubMed ID: 12421919
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphatidylinositol (3,4,5)P3 is essential but not sufficient for protein kinase B (PKB) activation; phosphatidylinositol (3,4)P2 is required for PKB phosphorylation at Ser-473: studies using cells from SH2-containing inositol-5-phosphatase knockout mice.
    Scheid MP; Huber M; Damen JE; Hughes M; Kang V; Neilsen P; Prestwich GD; Krystal G; Duronio V
    J Biol Chem; 2002 Mar; 277(11):9027-35. PubMed ID: 11781306
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Impact of transgenic overexpression of SH2-containing inositol 5'-phosphatase 2 on glucose metabolism and insulin signaling in mice.
    Kagawa S; Soeda Y; Ishihara H; Oya T; Sasahara M; Yaguchi S; Oshita R; Wada T; Tsuneki H; Sasaoka T
    Endocrinology; 2008 Feb; 149(2):642-50. PubMed ID: 18039790
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reversal of denervation-induced insulin resistance by SHIP2 protein synthesis blockade.
    Bertelli DF; Ueno M; Amaral ME; Toyama MH; Carneiro EM; Marangoni S; Carvalho CR; Saad MJ; Velloso LA; Boschero AC
    Am J Physiol Endocrinol Metab; 2003 Apr; 284(4):E679-87. PubMed ID: 12453826
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dual role of SRC homology domain 2-containing inositol phosphatase 2 in the regulation of platelet-derived growth factor and insulin-like growth factor I signaling in rat vascular smooth muscle cells.
    Sasaoka T; Kikuchi K; Wada T; Sato A; Hori H; Murakami S; Fukui K; Ishihara H; Aota R; Kimura I; Kobayashi M
    Endocrinology; 2003 Sep; 144(9):4204-14. PubMed ID: 12933696
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Insulin-induced activation of atypical protein kinase C, but not protein kinase B, is maintained in diabetic (ob/ob and Goto-Kakazaki) liver. Contrasting insulin signaling patterns in liver versus muscle define phenotypes of type 2 diabetic and high fat-induced insulin-resistant states.
    Standaert ML; Sajan MP; Miura A; Kanoh Y; Chen HC; Farese RV; Farese RV
    J Biol Chem; 2004 Jun; 279(24):24929-34. PubMed ID: 15069067
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Impact of the liver-specific expression of SHIP2 (SH2-containing inositol 5'-phosphatase 2) on insulin signaling and glucose metabolism in mice.
    Fukui K; Wada T; Kagawa S; Nagira K; Ikubo M; Ishihara H; Kobayashi M; Sasaoka T
    Diabetes; 2005 Jul; 54(7):1958-67. PubMed ID: 15983195
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Defective activation of atypical protein kinase C zeta and lambda by insulin and phosphatidylinositol-3,4,5-(PO4)(3) in skeletal muscle of rats following high-fat feeding and streptozotocin-induced diabetes.
    Kanoh Y; Sajan MP; Bandyopadhyay G; Miura A; Standaert ML; Farese RV
    Endocrinology; 2003 Mar; 144(3):947-54. PubMed ID: 12586772
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Impact of Src homology 2-containing inositol 5'-phosphatase 2 on the regulation of insulin signaling leading to protein synthesis in 3T3-L1 adipocytes cultured with excess amino acids.
    Murakami S; Sasaoka T; Wada T; Fukui K; Nagira K; Ishihara H; Usui I; Kobayashi M
    Endocrinology; 2004 Jul; 145(7):3215-23. PubMed ID: 15044364
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.