BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

285 related articles for article (PubMed ID: 12145277)

  • 21. Interleukin-6 inhibits transforming growth factor-beta-induced apoptosis through the phosphatidylinositol 3-kinase/Akt and signal transducers and activators of transcription 3 pathways.
    Chen RH; Chang MC; Su YH; Tsai YT; Kuo ML
    J Biol Chem; 1999 Aug; 274(33):23013-9. PubMed ID: 10438468
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Blocking of c-FLIP(L)--independent cycloheximide-induced apoptosis or Fas-mediated apoptosis by the CC chemokine receptor 9/TECK interaction.
    Youn BS; Kim YJ; Mantel C; Yu KY; Broxmeyer HE
    Blood; 2001 Aug; 98(4):925-33. PubMed ID: 11493434
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Increased O-glycosylation of insulin signaling proteins results in their impaired activation and enhanced susceptibility to apoptosis in pancreatic beta-cells.
    D'Alessandris C; Andreozzi F; Federici M; Cardellini M; Brunetti A; Ranalli M; Del Guerra S; Lauro D; Del Prato S; Marchetti P; Lauro R; Sesti G
    FASEB J; 2004 Jun; 18(9):959-61. PubMed ID: 15059979
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC.
    Haas-Kogan D; Shalev N; Wong M; Mills G; Yount G; Stokoe D
    Curr Biol; 1998 Oct; 8(21):1195-8. PubMed ID: 9799739
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Estradiol abrogates apoptosis in breast cancer cells through inactivation of BAD: Ras-dependent nongenomic pathways requiring signaling through ERK and Akt.
    Fernando RI; Wimalasena J
    Mol Biol Cell; 2004 Jul; 15(7):3266-84. PubMed ID: 15121878
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Adenovirus-mediated transfer of the PTEN gene inhibits human colorectal cancer growth in vitro and in vivo.
    Saito Y; Swanson X; Mhashilkar AM; Oida Y; Schrock R; Branch CD; Chada S; Zumstein L; Ramesh R
    Gene Ther; 2003 Nov; 10(23):1961-9. PubMed ID: 14528320
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics.
    Zhong H; Chiles K; Feldser D; Laughner E; Hanrahan C; Georgescu MM; Simons JW; Semenza GL
    Cancer Res; 2000 Mar; 60(6):1541-5. PubMed ID: 10749120
    [TBL] [Abstract][Full Text] [Related]  

  • 28. PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway.
    Tamura M; Gu J; Danen EH; Takino T; Miyamoto S; Yamada KM
    J Biol Chem; 1999 Jul; 274(29):20693-703. PubMed ID: 10400703
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Abnormal PTEN expression in portal hypertensive gastric mucosa: a key to impaired PI 3-kinase/Akt activation and delayed injury healing?
    Tsugawa K; Jones MK; Akahoshi T; Moon WS; Maehara Y; Hashizume M; Sarfeh IJ; Tarnawski AS
    FASEB J; 2003 Dec; 17(15):2316-8. PubMed ID: 14525948
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Activation of Akt (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression.
    Hutchinson J; Jin J; Cardiff RD; Woodgett JR; Muller WJ
    Mol Cell Biol; 2001 Mar; 21(6):2203-12. PubMed ID: 11238953
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The PI 3-kinase/Akt signaling pathway is activated due to aberrant Pten expression and targets transcription factors NF-kappaB and c-Myc in pancreatic cancer cells.
    Asano T; Yao Y; Zhu J; Li D; Abbruzzese JL; Reddy SA
    Oncogene; 2004 Nov; 23(53):8571-80. PubMed ID: 15467756
    [TBL] [Abstract][Full Text] [Related]  

  • 32. PTEN and TNF-alpha regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-kappaB-dependent pathway.
    Kim S; Domon-Dell C; Wang Q; Chung DH; Di Cristofano A; Pandolfi PP; Freund JN; Evers BM
    Gastroenterology; 2002 Oct; 123(4):1163-78. PubMed ID: 12360479
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Suppression of Akt signaling induces Fas ligand expression: involvement of caspase and Jun kinase activation in Akt-mediated Fas ligand regulation.
    Suhara T; Kim HS; Kirshenbaum LA; Walsh K
    Mol Cell Biol; 2002 Jan; 22(2):680-91. PubMed ID: 11756562
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Akt regulates COX-2 mRNA and protein expression in mutated-PTEN human endometrial cancer cells.
    St-Germain ME; Gagnon V; Mathieu I; Parent S; Asselin E
    Int J Oncol; 2004 May; 24(5):1311-24. PubMed ID: 15067356
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Role of the phosphatidylinositol 3'-kinase/PTEN/Akt kinase pathway in tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in non-small cell lung cancer cells.
    Kandasamy K; Srivastava RK
    Cancer Res; 2002 Sep; 62(17):4929-37. PubMed ID: 12208743
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Inactivation of the Akt survival pathway during photoreceptor apoptosis in the retinal degeneration mouse.
    Jomary C; Cullen J; Jones SE
    Invest Ophthalmol Vis Sci; 2006 Apr; 47(4):1620-9. PubMed ID: 16565401
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Hyaluronan constitutively regulates activation of COX-2-mediated cell survival activity in intestinal epithelial and colon carcinoma cells.
    Misra S; Obeid LM; Hannun YA; Minamisawa S; Berger FG; Markwald RR; Toole BP; Ghatak S
    J Biol Chem; 2008 May; 283(21):14335-44. PubMed ID: 18326857
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The PI3-kinase-Akt pathway promotes mesangial cell survival and inhibits apoptosis in vitro via NF-kappa B and Bad.
    Shimamura H; Terada Y; Okado T; Tanaka H; Inoshita S; Sasaki S
    J Am Soc Nephrol; 2003 Jun; 14(6):1427-34. PubMed ID: 12761242
    [TBL] [Abstract][Full Text] [Related]  

  • 39. HGF protects corneal epithelial cells from apoptosis by the PI-3K/Akt-1/Bad- but not the ERK1/2-mediated signaling pathway.
    Kakazu A; Chandrasekher G; Bazan HE
    Invest Ophthalmol Vis Sci; 2004 Oct; 45(10):3485-92. PubMed ID: 15452053
    [TBL] [Abstract][Full Text] [Related]  

  • 40. The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway.
    Arico S; Petiot A; Bauvy C; Dubbelhuis PF; Meijer AJ; Codogno P; Ogier-Denis E
    J Biol Chem; 2001 Sep; 276(38):35243-6. PubMed ID: 11477064
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.