BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

519 related articles for article (PubMed ID: 12145326)

  • 1. Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects.
    Zhu X; Zhou A; Dey A; Norrbom C; Carroll R; Zhang C; Laurent V; Lindberg I; Ugleholdt R; Holst JJ; Steiner DF
    Proc Natl Acad Sci U S A; 2002 Aug; 99(16):10293-8. PubMed ID: 12145326
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Impaired intestinal proglucagon processing in mice lacking prohormone convertase 1.
    Ugleholdt R; Zhu X; Deacon CF; Ørskov C; Steiner DF; Holst JJ
    Endocrinology; 2004 Mar; 145(3):1349-55. PubMed ID: 14630721
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differential processing of proglucagon by the subtilisin-like prohormone convertases PC2 and PC3 to generate either glucagon or glucagon-like peptide.
    Rouillé Y; Martin S; Steiner DF
    J Biol Chem; 1995 Nov; 270(44):26488-96. PubMed ID: 7592866
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Incomplete processing of proinsulin to insulin accompanied by elevation of Des-31,32 proinsulin intermediates in islets of mice lacking active PC2.
    Furuta M; Carroll R; Martin S; Swift HH; Ravazzola M; Orci L; Steiner DF
    J Biol Chem; 1998 Feb; 273(6):3431-7. PubMed ID: 9452465
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Proglucagon processing in an islet cell line: effects of PC1 overexpression and PC2 depletion.
    Dhanvantari S; Brubaker PL
    Endocrinology; 1998 Apr; 139(4):1630-7. PubMed ID: 9528943
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Severe block in processing of proinsulin to insulin accompanied by elevation of des-64,65 proinsulin intermediates in islets of mice lacking prohormone convertase 1/3.
    Zhu X; Orci L; Carroll R; Norrbom C; Ravazzola M; Steiner DF
    Proc Natl Acad Sci U S A; 2002 Aug; 99(16):10299-304. PubMed ID: 12136131
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Severe defect in proglucagon processing in islet A-cells of prohormone convertase 2 null mice.
    Furuta M; Zhou A; Webb G; Carroll R; Ravazzola M; Orci L; Steiner DF
    J Biol Chem; 2001 Jul; 276(29):27197-202. PubMed ID: 11356850
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regulation of pancreatic PC1 and PC2 associated with increased glucagon-like peptide 1 in diabetic rats.
    Nie Y; Nakashima M; Brubaker PL; Li QL; Perfetti R; Jansen E; Zambre Y; Pipeleers D; Friedman TC
    J Clin Invest; 2000 Apr; 105(7):955-65. PubMed ID: 10749575
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Furin and prohormone convertase 1/3 are major convertases in the processing of mouse pro-growth hormone-releasing hormone.
    Dey A; Norrbom C; Zhu X; Stein J; Zhang C; Ueda K; Steiner DF
    Endocrinology; 2004 Apr; 145(4):1961-71. PubMed ID: 14684599
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Impaired prohormone convertases in Cpe(fat)/Cpe(fat) mice.
    Berman Y; Mzhavia N; Polonskaia A; Devi LA
    J Biol Chem; 2001 Jan; 276(2):1466-73. PubMed ID: 11038363
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In vitro processing of proopiomelanocortin by recombinant PC1 (SPC3).
    Friedman TC; Loh YP; Birch NP
    Endocrinology; 1994 Sep; 135(3):854-62. PubMed ID: 8070378
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The role of prohormone convertases PC1 (PC3) and PC2 in the cell-specific processing of proglucagon.
    Mineo I; Matsumura T; Shingu R; Namba M; Kuwajima M; Matsuzawa Y
    Biochem Biophys Res Commun; 1995 Feb; 207(2):646-51. PubMed ID: 7864855
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Processing of mouse proglucagon by recombinant prohormone convertase 1 and immunopurified prohormone convertase 2 in vitro.
    Rothenberg ME; Eilertson CD; Klein K; Zhou Y; Lindberg I; McDonald JK; Mackin RB; Noe BD
    J Biol Chem; 1995 Apr; 270(17):10136-46. PubMed ID: 7730317
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Coregulation of glucagon-like peptide-1 synthesis with proglucagon and prohormone convertase 1 gene expression in enteroendocrine GLUTag cells.
    Dhanvantari S; Izzo A; Jansen E; Brubaker PL
    Endocrinology; 2001 Jan; 142(1):37-42. PubMed ID: 11145564
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of prohormone convertases in pro-neuropeptide Y processing: coexpression and in vitro kinetic investigations.
    Brakch N; Rist B; Beck-Sickinger AG; Goenaga J; Wittek R; Bürger E; Brunner HR; Grouzmann E
    Biochemistry; 1997 Dec; 36(51):16309-20. PubMed ID: 9405066
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Biological processing of the cocaine and amphetamine-regulated transcript precursors by prohormone convertases, PC2 and PC1/3.
    Dey A; Xhu X; Carroll R; Turck CW; Stein J; Steiner DF
    J Biol Chem; 2003 Apr; 278(17):15007-14. PubMed ID: 12584191
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Proglucagon processing profile in canine L cells expressing endogenous prohormone convertase 1/3 and prohormone convertase 2.
    Damholt AB; Buchan AM; Holst JJ; Kofod H
    Endocrinology; 1999 Oct; 140(10):4800-8. PubMed ID: 10499540
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PC1/3 and PC2 gene expression and post-translational endoproteolytic pro-opiomelanocortin processing is regulated by photoperiod in the seasonal Siberian hamster (Phodopus sungorus).
    Helwig M; Khorooshi RM; Tups A; Barrett P; Archer ZA; Exner C; Rozman J; Braulke LJ; Mercer JG; Klingenspor M
    J Neuroendocrinol; 2006 Jun; 18(6):413-25. PubMed ID: 16684131
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Post-translational processing of proopiomelanocortin (POMC) in mouse pituitary melanotroph tumors induced by a POMC-simian virus 40 large T antigen transgene.
    Low MJ; Liu B; Hammer GD; Rubinstein M; Allen RG
    J Biol Chem; 1993 Nov; 268(33):24967-75. PubMed ID: 8227058
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Maintained PC1 and PC2 expression in the AtT-20 variant cell line 6T3 lacking regulated secretion and POMC: restored POMC expression and regulated secretion after cAMP treatment.
    Day R; Benjannet S; Matsuuchi L; Kelly RB; Marcinkiewicz M; Chrétien M; Seidah NG
    DNA Cell Biol; 1995 Feb; 14(2):175-88. PubMed ID: 7865135
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.