351 related articles for article (PubMed ID: 12145346)
1. Insulin receptor substrate-1 and phosphoinositide-dependent kinase-1 are required for insulin-stimulated production of nitric oxide in endothelial cells.
Montagnani M; Ravichandran LV; Chen H; Esposito DL; Quon MJ
Mol Endocrinol; 2002 Aug; 16(8):1931-42. PubMed ID: 12145346
[TBL] [Abstract][Full Text] [Related]
2. Angiotensin II impairs the insulin signaling pathway promoting production of nitric oxide by inducing phosphorylation of insulin receptor substrate-1 on Ser312 and Ser616 in human umbilical vein endothelial cells.
Andreozzi F; Laratta E; Sciacqua A; Perticone F; Sesti G
Circ Res; 2004 May; 94(9):1211-8. PubMed ID: 15044323
[TBL] [Abstract][Full Text] [Related]
3. G972R IRS-1 variant impairs insulin regulation of endothelial nitric oxide synthase in cultured human endothelial cells.
Federici M; Pandolfi A; De Filippis EA; Pellegrini G; Menghini R; Lauro D; Cardellini M; Romano M; Sesti G; Lauro R; Consoli A
Circulation; 2004 Jan; 109(3):399-405. PubMed ID: 14707024
[TBL] [Abstract][Full Text] [Related]
4. Insulin-stimulated activation of eNOS is independent of Ca2+ but requires phosphorylation by Akt at Ser(1179).
Montagnani M; Chen H; Barr VA; Quon MJ
J Biol Chem; 2001 Aug; 276(32):30392-8. PubMed ID: 11402048
[TBL] [Abstract][Full Text] [Related]
5. Adiponectin stimulates production of nitric oxide in vascular endothelial cells.
Chen H; Montagnani M; Funahashi T; Shimomura I; Quon MJ
J Biol Chem; 2003 Nov; 278(45):45021-6. PubMed ID: 12944390
[TBL] [Abstract][Full Text] [Related]
6. Interleukin-6 impairs the insulin signaling pathway, promoting production of nitric oxide in human umbilical vein endothelial cells.
Andreozzi F; Laratta E; Procopio C; Hribal ML; Sciacqua A; Perticone M; Miele C; Perticone F; Sesti G
Mol Cell Biol; 2007 Mar; 27(6):2372-83. PubMed ID: 17242212
[TBL] [Abstract][Full Text] [Related]
7. Free fatty acid impairment of nitric oxide production in endothelial cells is mediated by IKKbeta.
Kim F; Tysseling KA; Rice J; Pham M; Haji L; Gallis BM; Baas AS; Paramsothy P; Giachelli CM; Corson MA; Raines EW
Arterioscler Thromb Vasc Biol; 2005 May; 25(5):989-94. PubMed ID: 15731493
[TBL] [Abstract][Full Text] [Related]
8. High glucose inhibits insulin-stimulated nitric oxide production without reducing endothelial nitric-oxide synthase Ser1177 phosphorylation in human aortic endothelial cells.
Salt IP; Morrow VA; Brandie FM; Connell JM; Petrie JR
J Biol Chem; 2003 May; 278(21):18791-7. PubMed ID: 12644458
[TBL] [Abstract][Full Text] [Related]
9. A novel T608R missense mutation in insulin receptor substrate-1 identified in a subject with type 2 diabetes impairs metabolic insulin signaling.
Esposito DL; Li Y; Vanni C; Mammarella S; Veschi S; Della Loggia F; Mariani-Costantini R; Battista P; Quon MJ; Cama A
J Clin Endocrinol Metab; 2003 Apr; 88(4):1468-75. PubMed ID: 12679424
[TBL] [Abstract][Full Text] [Related]
10. Dehydroepiandrosterone mimics acute actions of insulin to stimulate production of both nitric oxide and endothelin 1 via distinct phosphatidylinositol 3-kinase- and mitogen-activated protein kinase-dependent pathways in vascular endothelium.
Formoso G; Chen H; Kim JA; Montagnani M; Consoli A; Quon MJ
Mol Endocrinol; 2006 May; 20(5):1153-63. PubMed ID: 16373398
[TBL] [Abstract][Full Text] [Related]
11. Losartan improves aortic endothelium-dependent relaxation via proline-rich tyrosine kinase 2/Src/Akt pathway in type 2 diabetic Goto-Kakizaki rats.
Nemoto S; Kobayashi T; Taguchi K; Matsumoto T; Kamata K
Am J Physiol Heart Circ Physiol; 2011 Dec; 301(6):H2383-94. PubMed ID: 21926342
[TBL] [Abstract][Full Text] [Related]
12. Ghrelin has novel vascular actions that mimic PI 3-kinase-dependent actions of insulin to stimulate production of NO from endothelial cells.
Iantorno M; Chen H; Kim JA; Tesauro M; Lauro D; Cardillo C; Quon MJ
Am J Physiol Endocrinol Metab; 2007 Mar; 292(3):E756-64. PubMed ID: 17106060
[TBL] [Abstract][Full Text] [Related]
13. Tyrosine phosphorylation of phosphoinositide-dependent kinase 1 by the insulin receptor is necessary for insulin metabolic signaling.
Fiory F; Alberobello AT; Miele C; Oriente F; Esposito I; Corbo V; Ruvo M; Tizzano B; Rasmussen TE; Gammeltoft S; Formisano P; Beguinot F
Mol Cell Biol; 2005 Dec; 25(24):10803-14. PubMed ID: 16314505
[TBL] [Abstract][Full Text] [Related]
14. Mechanism of hyperhomocysteinemia-induced vascular endothelium dysfunction - possible dysregulation of phosphatidylinositol-3-kinase and its downstream phosphoinositide dependent kinase and protein kinase B.
Sharma S; Singh M; Sharma PL
Eur J Pharmacol; 2013 Dec; 721(1-3):365-72. PubMed ID: 24021535
[TBL] [Abstract][Full Text] [Related]
15. Activation of the PDK-1/Akt/eNOS pathway involved in aortic endothelial function differs between hyperinsulinemic and insulin-deficient diabetic rats.
Kobayashi T; Taguchi K; Nemoto S; Nogami T; Matsumoto T; Kamata K
Am J Physiol Heart Circ Physiol; 2009 Nov; 297(5):H1767-75. PubMed ID: 19717727
[TBL] [Abstract][Full Text] [Related]
16. C-reactive protein suppresses insulin signaling in endothelial cells: role of spleen tyrosine kinase.
Xu JW; Morita I; Ikeda K; Miki T; Yamori Y
Mol Endocrinol; 2007 Feb; 21(2):564-73. PubMed ID: 17095576
[TBL] [Abstract][Full Text] [Related]
17. Estrogen receptor activation of phosphoinositide-3 kinase, akt, and nitric oxide signaling in cerebral blood vessels: rapid and long-term effects.
Stirone C; Boroujerdi A; Duckles SP; Krause DN
Mol Pharmacol; 2005 Jan; 67(1):105-13. PubMed ID: 15496504
[TBL] [Abstract][Full Text] [Related]
18. Tumor necrosis factor-alpha induces insulin resistance in endothelial cells via a p38 mitogen-activated protein kinase-dependent pathway.
Li G; Barrett EJ; Barrett MO; Cao W; Liu Z
Endocrinology; 2007 Jul; 148(7):3356-63. PubMed ID: 17446186
[TBL] [Abstract][Full Text] [Related]
19. Diosgenin ameliorates palmitate-induced endothelial dysfunction and insulin resistance via blocking IKKβ and IRS-1 pathways.
Liu K; Zhao W; Gao X; Huang F; Kou J; Liu B
Atherosclerosis; 2012 Aug; 223(2):350-8. PubMed ID: 22766331
[TBL] [Abstract][Full Text] [Related]
20. TNF-alpha inhibits flow and insulin signaling leading to NO production in aortic endothelial cells.
Kim F; Gallis B; Corson MA
Am J Physiol Cell Physiol; 2001 May; 280(5):C1057-65. PubMed ID: 11287317
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
