BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

173 related articles for article (PubMed ID: 12148910)

  • 1. Treatment of refractory acute leukemia with timed sequential chemotherapy using topotecan followed by etoposide + mitoxantrone (T-EM) and correlation with topoisomerase II levels.
    Mainwaring MG; Rimsza LM; Chen SF; Gomez SP; Weeks FW; Reddy V; Lynch J; May WS; Kahn S; Moreb J; Leather H; Braylan R; Rowe TC; Fieniewicz KJ; Wingard JR
    Leuk Lymphoma; 2002 May; 43(5):989-99. PubMed ID: 12148910
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phase I trial of sequential topotecan followed by etoposide in adults with myeloid leukemia: a National Cancer Institute of Canada Clinical Trials Group Study.
    Crump M; Lipton J; Hedley D; Sutton D; Shepherd F; Minden M; Stewart K; Beare S; Eisenhauer E
    Leukemia; 1999 Mar; 13(3):343-7. PubMed ID: 10086724
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Topotecan-induced topoisomerase IIalpha expression increases the sensitivity of the CML cell line K562 to subsequent etoposide plus mitoxantrone treatment.
    Chen S; Gomez SP; McCarley D; Mainwaring MG
    Cancer Chemother Pharmacol; 2002 May; 49(5):347-55. PubMed ID: 11976828
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A phase I and translational study of sequential administration of the topoisomerase I and II inhibitors topotecan and etoposide.
    Hammond LA; Eckardt JR; Ganapathi R; Burris HA; Rodriguez GA; Eckhardt SG; Rothenberg ML; Weiss GR; Kuhn JG; Hodges S; Von Hoff DD; Rowinsky EK
    Clin Cancer Res; 1998 Jun; 4(6):1459-67. PubMed ID: 9626463
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evaluation of topotecan and etoposide for non-Hodgkin lymphoma: correlation of topoisomerase-DNA complex formation with clinical response.
    Kancherla RR; Nair JS; Ahmed T; Durrani H; Seiter K; Mannancheril A; Tse-Dinh YC
    Cancer; 2001 Feb; 91(3):463-71. PubMed ID: 11169927
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A phase I and pharmacodynamic study of sequential topotecan and etoposide in patients with relapsed or refractory acute myelogenous and lymphoblastic leukemia.
    Cooper BW; Donaher E; Lazarus HM; Green SB; Gosky DM; Rosenthal NS; Berger SJ; Li X; Ingalls ST; Hoppel CL; Gerson SL
    Leuk Res; 2003 Jan; 27(1):35-44. PubMed ID: 12479850
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phase II and pharmacokinetic/pharmacodynamic trial of sequential topoisomerase I and II inhibition with topotecan and etoposide in advanced non-small-cell lung cancer.
    Dowlati A; Levitan N; Gordon NH; Hoppel CL; Gosky DM; Remick SC; Ingalls ST; Berger SJ; Berger NA
    Cancer Chemother Pharmacol; 2001; 47(2):141-8. PubMed ID: 11269740
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phase I and pharmacologic study of sequential topotecan-carboplatin-etoposide in patients with extensive stage small cell lung cancer.
    Miller AA; Al Omari A; Murry DJ; Case D
    Lung Cancer; 2006 Dec; 54(3):379-85. PubMed ID: 17049403
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sequential topoisomerase targeting and analysis of mechanisms of resistance to topotecan in patients with acute myelogenous leukemia.
    Saraiya B; Gounder M; Dutta J; Saleem A; Collazo C; Zimmerman L; Nazar A; Gharibo M; Schaar D; Lin Y; Shih W; Aisner J; Strair RK; Rubin EH
    Anticancer Drugs; 2008 Apr; 19(4):411-20. PubMed ID: 18454051
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Topotecan increases topoisomerase IIalpha levels and sensitivity to treatment with etoposide in schedule-dependent process.
    Whitacre CM; Zborowska E; Gordon NH; Mackay W; Berger NA
    Cancer Res; 1997 Apr; 57(8):1425-8. PubMed ID: 9108439
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dose-escalation study of single dose mitoxantrone in combination with timed sequential chemotherapy in patients with refractory or relapsing acute myelogenous leukemia.
    Thomas X; Cambier N; Taksin AL; Reman O; Vekhoff A; Pautas C; Leblond V; Soler-Michel P; Ecstein-Fraïssé E; Archimbaud E
    Leuk Res; 2000 Nov; 24(11):957-63. PubMed ID: 11086179
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phase II study of sequential topotecan and etoposide in patients with intermediate grade non-Hodgkin's lymphoma: a National Cancer Institute of Canada Clinical Trials Group study.
    Crump M; Couban S; Meyer R; Rudinskas L; Zanke B; Gluck S; Maksymiuk A; Hoskins P; Matthews S; Eisenhauer E
    Leuk Lymphoma; 2002 Aug; 43(8):1581-7. PubMed ID: 12400600
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Time sequential chemotherapy for primary refractory or relapsed adult acute myeloid leukemia: results of the phase II Gemia protocol.
    Martino R; Guardia R; Altés A; Sureda A; Brunet S; Sierra J
    Haematologica; 1999 Mar; 84(3):226-30. PubMed ID: 10189387
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A phase I and pharmacological study of topotecan infused over 30 minutes for five days in patients with refractory acute leukemia.
    Rowinsky EK; Kaufmann SH; Baker SD; Miller CB; Sartorius SE; Bowling MK; Chen TL; Donehower RC; Gore SD
    Clin Cancer Res; 1996 Dec; 2(12):1921-30. PubMed ID: 9816150
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phase I and pharmacodynamic study of the topoisomerase I-inhibitor topotecan in patients with refractory acute leukemia.
    Rowinsky EK; Adjei A; Donehower RC; Gore SD; Jones RJ; Burke PJ; Cheng YC; Grochow LB; Kaufmann SH
    J Clin Oncol; 1994 Oct; 12(10):2193-203. PubMed ID: 7931489
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A Phase I-II study of sequential administration of topotecan and oral etoposide (toposiomerase I and II inhibitors) in the treatment of patients with small cell lung carcinoma.
    Mok TS; Wong H; Zee B; Yu KH; Leung TW; Lee TW; Yim A; Chan AT; Yeo W; Chak K; Johnson P
    Cancer; 2002 Oct; 95(7):1511-9. PubMed ID: 12237920
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phase I and pharmacologic study of infusional topotecan and Carboplatin in relapsed and refractory acute leukemia.
    Kaufmann SH; Karp JE; Letendre L; Kottke TJ; Safgren S; Greer J; Gojo I; Atherton P; Svingen PA; Loegering DA; Litzow MR; Sloan JA; Reid JM; Ames MM; Adjei AA; Erlichman C
    Clin Cancer Res; 2005 Sep; 11(18):6641-9. PubMed ID: 16166443
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A phase I study of sequential intravenous topotecan and etoposide in lung cancer patients.
    Huisman C; Postmus PE; Giaccone G; Smit EF
    Ann Oncol; 2001 Nov; 12(11):1567-73. PubMed ID: 11822756
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Action of topoisomerase targeting drugs on non-Hodgkin's lymphoma and leukemia. Correlation of clinical and cell culture studies.
    Nair JS; Kancherla R; Seiter K; Traganos F; Tse-Dinh YC
    Ann N Y Acad Sci; 2000; 922():326-9. PubMed ID: 11193914
    [No Abstract]   [Full Text] [Related]  

  • 20. Topoisomerase IIalpha and other drug resistance markers in advanced non-small cell lung cancer.
    Dingemans AC; van Ark-Otte J; Span S; Scagliotti GV; van der Valk P; Postmus PE; Giaccone G
    Lung Cancer; 2001 May; 32(2):117-28. PubMed ID: 11325482
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.