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6. Wild type Huntingtin reduces the cellular toxicity of mutant Huntingtin in mammalian cell models of Huntington's disease. Ho LW; Brown R; Maxwell M; Wyttenbach A; Rubinsztein DC J Med Genet; 2001 Jul; 38(7):450-2. PubMed ID: 11432963 [TBL] [Abstract][Full Text] [Related]
8. Mutant protein in Huntington disease is resistant to proteolysis in affected brain. Dyer RB; McMurray CT Nat Genet; 2001 Nov; 29(3):270-8. PubMed ID: 11600884 [TBL] [Abstract][Full Text] [Related]
9. Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release. Choo YS; Johnson GV; MacDonald M; Detloff PJ; Lesort M Hum Mol Genet; 2004 Jul; 13(14):1407-20. PubMed ID: 15163634 [TBL] [Abstract][Full Text] [Related]
10. Age-dependent changes in the calcium sensitivity of striatal mitochondria in mouse models of Huntington's Disease. Brustovetsky N; LaFrance R; Purl KJ; Brustovetsky T; Keene CD; Low WC; Dubinsky JM J Neurochem; 2005 Jun; 93(6):1361-70. PubMed ID: 15935052 [TBL] [Abstract][Full Text] [Related]
11. In vitro effects of polyglutamine tracts on Ca2+-dependent depolarization of rat and human mitochondria: relevance to Huntington's disease. Panov AV; Burke JR; Strittmatter WJ; Greenamyre JT Arch Biochem Biophys; 2003 Feb; 410(1):1-6. PubMed ID: 12559971 [TBL] [Abstract][Full Text] [Related]
12. Phosphorylation of huntingtin by cyclin-dependent kinase 5 is induced by DNA damage and regulates wild-type and mutant huntingtin toxicity in neurons. Anne SL; Saudou F; Humbert S J Neurosci; 2007 Jul; 27(27):7318-28. PubMed ID: 17611284 [TBL] [Abstract][Full Text] [Related]
13. Normal and mutant huntingtin: partners in crime. Di Prospero NA; Tagle DA Nat Med; 2000 Nov; 6(11):1208-9. PubMed ID: 11062523 [No Abstract] [Full Text] [Related]
14. Paradoxical aggregation versus oligomerisation properties of mutant and wild-type huntingtin fragments. Rubinsztein DC; Huntington JA Exp Neurol; 2006 Jun; 199(2):243-4. PubMed ID: 16631742 [No Abstract] [Full Text] [Related]
16. Association between BDNF Val66Met polymorphism and age at onset in Huntington disease. Alberch J; López M; Badenas C; Carrasco JL; Milà M; Muñoz E; Canals JM Neurology; 2005 Sep; 65(6):964-5. PubMed ID: 16186551 [No Abstract] [Full Text] [Related]
17. Differential vulnerability of neurons in Huntington's disease: the role of cell type-specific features. Han I; You Y; Kordower JH; Brady ST; Morfini GA J Neurochem; 2010 Jun; 113(5):1073-91. PubMed ID: 20236390 [TBL] [Abstract][Full Text] [Related]
18. Environmental enrichment rescues protein deficits in a mouse model of Huntington's disease, indicating a possible disease mechanism. Spires TL; Grote HE; Varshney NK; Cordery PM; van Dellen A; Blakemore C; Hannan AJ J Neurosci; 2004 Mar; 24(9):2270-6. PubMed ID: 14999077 [TBL] [Abstract][Full Text] [Related]
19. Microtubule destabilization and nuclear entry are sequential steps leading to toxicity in Huntington's disease. Trushina E; Heldebrant MP; Perez-Terzic CM; Bortolon R; Kovtun IV; Badger JD; Terzic A; Estévez A; Windebank AJ; Dyer RB; Yao J; McMurray CT Proc Natl Acad Sci U S A; 2003 Oct; 100(21):12171-6. PubMed ID: 14527999 [TBL] [Abstract][Full Text] [Related]