These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1134 related articles for article (PubMed ID: 12149650)

  • 21. PTEN augments staurosporine-induced apoptosis in PTEN-null Ishikawa cells by downregulating PI3K/Akt signaling pathway.
    Wan X; Yokoyama Y; Shinohara A; Takahashi Y; Tamaya T
    Cell Death Differ; 2002 Apr; 9(4):414-20. PubMed ID: 11965494
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway.
    Ramaswamy S; Nakamura N; Vazquez F; Batt DB; Perera S; Roberts TM; Sellers WR
    Proc Natl Acad Sci U S A; 1999 Mar; 96(5):2110-5. PubMed ID: 10051603
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The inositol 5'-phosphatase SHIP-1 and the Src kinase Lyn negatively regulate macrophage colony-stimulating factor-induced Akt activity.
    Baran CP; Tridandapani S; Helgason CD; Humphries RK; Krystal G; Marsh CB
    J Biol Chem; 2003 Oct; 278(40):38628-36. PubMed ID: 12882960
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Enhanced sensitivity of multiple myeloma cells containing PTEN mutations to CCI-779.
    Shi Y; Gera J; Hu L; Hsu JH; Bookstein R; Li W; Lichtenstein A
    Cancer Res; 2002 Sep; 62(17):5027-34. PubMed ID: 12208757
    [TBL] [Abstract][Full Text] [Related]  

  • 25. SH2-containing inositol phosphatase 2 predominantly regulates Akt2, and not Akt1, phosphorylation at the plasma membrane in response to insulin in 3T3-L1 adipocytes.
    Sasaoka T; Wada T; Fukui K; Murakami S; Ishihara H; Suzuki R; Tobe K; Kadowaki T; Kobayashi M
    J Biol Chem; 2004 Apr; 279(15):14835-43. PubMed ID: 14744864
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Impact of PTEN on the expression of insulin-like growth factors (IGFs) and IGF-binding proteins in human gastric adenocarcinoma cells.
    Yi HK; Kim SY; Hwang PH; Kim CY; Yang DH; Oh Y; Lee DY
    Biochem Biophys Res Commun; 2005 May; 330(3):760-7. PubMed ID: 15809062
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Akt regulates COX-2 mRNA and protein expression in mutated-PTEN human endometrial cancer cells.
    St-Germain ME; Gagnon V; Mathieu I; Parent S; Asselin E
    Int J Oncol; 2004 May; 24(5):1311-24. PubMed ID: 15067356
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Loss of tumor suppressor p53 decreases PTEN expression and enhances signaling pathways leading to activation of activator protein 1 and nuclear factor kappaB induced by UV radiation.
    Wang J; Ouyang W; Li J; Wei L; Ma Q; Zhang Z; Tong Q; He J; Huang C
    Cancer Res; 2005 Aug; 65(15):6601-11. PubMed ID: 16061640
    [TBL] [Abstract][Full Text] [Related]  

  • 29. SHP-2 regulates the phosphatidylinositide 3'-kinase/Akt pathway and suppresses caspase 3-mediated apoptosis.
    Ivins Zito C; Kontaridis MI; Fornaro M; Feng GS; Bennett AM
    J Cell Physiol; 2004 May; 199(2):227-36. PubMed ID: 15040005
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Resistance to gefitinib in PTEN-null HER-overexpressing tumor cells can be overcome through restoration of PTEN function or pharmacologic modulation of constitutive phosphatidylinositol 3'-kinase/Akt pathway signaling.
    She QB; Solit D; Basso A; Moasser MM
    Clin Cancer Res; 2003 Oct; 9(12):4340-6. PubMed ID: 14555504
    [TBL] [Abstract][Full Text] [Related]  

  • 31. SHIP2 is recruited to the cell membrane upon macrophage colony-stimulating factor (M-CSF) stimulation and regulates M-CSF-induced signaling.
    Wang Y; Keogh RJ; Hunter MG; Mitchell CA; Frey RS; Javaid K; Malik AB; Schurmans S; Tridandapani S; Marsh CB
    J Immunol; 2004 Dec; 173(11):6820-30. PubMed ID: 15557176
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Regulation of sensitivity to TRAIL by the PTEN tumor suppressor.
    Whang YE; Yuan XJ; Liu Y; Majumder S; Lewis TD
    Vitam Horm; 2004; 67():409-26. PubMed ID: 15110188
    [TBL] [Abstract][Full Text] [Related]  

  • 33. The phosphatidylinositol 3-kinase/AKT kinase pathway in multiple myeloma plasma cells: roles in cytokine-dependent survival and proliferative responses.
    Tu Y; Gardner A; Lichtenstein A
    Cancer Res; 2000 Dec; 60(23):6763-70. PubMed ID: 11118064
    [TBL] [Abstract][Full Text] [Related]  

  • 34. [Inhibitory effect of lentiviral vector-mediated SHIP gene transfection on proliferation of leukemia K562 cells and PI3K/Akt pathway regulation].
    Yang L; Luo JM; Liu XJ; Wen SP; Du XY; Yao L
    Ai Zheng; 2009 Apr; 28(4):366-72. PubMed ID: 19622295
    [TBL] [Abstract][Full Text] [Related]  

  • 35. PTEN/MMAC1 overexpression decreases insulin-like growth factor-I-mediated protection from apoptosis in neuroblastoma cells.
    van Golen CM; Schwab TS; Ignatoski KM; Ethier SP; Feldman EL
    Cell Growth Differ; 2001 Jul; 12(7):371-8. PubMed ID: 11457734
    [TBL] [Abstract][Full Text] [Related]  

  • 36. A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells.
    Martelli AM; Tazzari PL; Tabellini G; Bortul R; Billi AM; Manzoli L; Ruggeri A; Conte R; Cocco L
    Leukemia; 2003 Sep; 17(9):1794-805. PubMed ID: 12970779
    [TBL] [Abstract][Full Text] [Related]  

  • 37. AKT activation up-regulates insulin-like growth factor I receptor expression and promotes invasiveness of human pancreatic cancer cells.
    Tanno S; Tanno S; Mitsuuchi Y; Altomare DA; Xiao GH; Testa JR
    Cancer Res; 2001 Jan; 61(2):589-93. PubMed ID: 11212254
    [TBL] [Abstract][Full Text] [Related]  

  • 38. [The mechanism for SHIP gene to induce the apoptosis of human leukemia cell line K562.].
    Yang L; Luo JM; Liu XJ; Wen SP; Du XY; Yao L; Yang JC
    Sheng Li Xue Bao; 2009 Apr; 61(2):146-54. PubMed ID: 19377826
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Her-2/neu overexpression induces NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN.
    Pianetti S; Arsura M; Romieu-Mourez R; Coffey RJ; Sonenshein GE
    Oncogene; 2001 Mar; 20(11):1287-99. PubMed ID: 11313873
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Serum withdrawal-induced accumulation of phosphoinositide 3-kinase lipids in differentiating 3T3-L6 myoblasts: distinct roles for Ship2 and PTEN.
    Mandl A; Sarkes D; Carricaburu V; Jung V; Rameh L
    Mol Cell Biol; 2007 Dec; 27(23):8098-112. PubMed ID: 17893321
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 57.