242 related articles for article (PubMed ID: 12160905)
1. Genotoxic activation of benzophenone and its two metabolites by human cytochrome P450s in SOS/umu assay.
Takemoto K; Yamazaki H; Nakajima M; Yokoi T
Mutat Res; 2002 Aug; 519(1-2):199-204. PubMed ID: 12160905
[TBL] [Abstract][Full Text] [Related]
2. Metabolic activation of carcinogenic 1-nitropyrene by human cytochrome P450 1B1 in Salmonella typhimurium strain expressing an O-acetyltransferase in SOS/umu assay.
Hatanaka N; Yamazaki H; Oda Y; Guengerich FP; Nakajima M; Yokoi T
Mutat Res; 2001 Oct; 497(1-2):223-33. PubMed ID: 11525925
[TBL] [Abstract][Full Text] [Related]
3. Bioactivation of diesel exhaust particle extracts and their major nitrated polycyclic aromatic hydrocarbon components, 1-nitropyrene and dinitropyrenes, by human cytochromes P450 1A1, 1A2, and 1B1.
Yamazaki H; Hatanaka N; Kizu R; Hayakawa K; Shimada N; Guengerich FP; Nakajima M; Yokoi T
Mutat Res; 2000 Dec; 472(1-2):129-38. PubMed ID: 11113705
[TBL] [Abstract][Full Text] [Related]
4. Metabolic activation of heterocyclic amines and other procarcinogens in Salmonella typhimurium umu tester strains expressing human cytochrome P4501A1, 1A2, 1B1, 2C9, 2D6, 2E1, and 3A4 and human NADPH-P450 reductase and bacterial O-acetyltransferase.
Oda Y; Aryal P; Terashita T; Gillam EM; Guengerich FP; Shimada T
Mutat Res; 2001 May; 492(1-2):81-90. PubMed ID: 11377247
[TBL] [Abstract][Full Text] [Related]
5. Escherichia coli MTC, a human NADPH P450 reductase competent mutagenicity tester strain for the expression of human cytochrome P450 isoforms 1A1, 1A2, 2A6, 3A4, or 3A5: catalytic activities and mutagenicity studies.
Kranendonk M; Carreira F; Theisen P; Laires A; Fisher CW; Rueff J; Estabrook RW; Vermeulen NP
Mutat Res; 1999 Apr; 441(1):73-83. PubMed ID: 10224324
[TBL] [Abstract][Full Text] [Related]
6. Use of genetically engineered Salmonella typhimurium OY1002/1A2 strain coexpressing human cytochrome P450 1A2 and NADPH-cytochrome P450 reductase and bacterial O-acetyltransferase in SOS/umu assay.
Aryal P; Terashita T; Guengerich FP; Shimada T; Oda Y
Environ Mol Mutagen; 2000; 36(2):121-6. PubMed ID: 11013410
[TBL] [Abstract][Full Text] [Related]
7. Role of human cytochrome P450 (CYP) in the metabolic activation of N-alkylnitrosamines: application of genetically engineered Salmonella typhimurium YG7108 expressing each form of CYP together with human NADPH-cytochrome P450 reductase.
Fujita K; Kamataki T
Mutat Res; 2001 Nov; 483(1-2):35-41. PubMed ID: 11600130
[TBL] [Abstract][Full Text] [Related]
8. Development of a Salmonella tester strain sensitive to promutagenic N-nitrosamines: expression of recombinant CYP2A6 and human NADPH-cytochrome P450 reductase in S. typhimurium YG7108.
Kushida H; Fujita K; Suzuki A; Yamada M; Nohmi T; Kamataki T
Mutat Res; 2000 Nov; 471(1-2):135-43. PubMed ID: 11080669
[TBL] [Abstract][Full Text] [Related]
9. Metabolism of benzo[a]pyrene to trans-7,8-dihydroxy-7, 8-dihydrobenzo[a]pyrene by recombinant human cytochrome P450 1B1 and purified liver epoxide hydrolase.
Shimada T; Gillam EM; Oda Y; Tsumura F; Sutter TR; Guengerich FP; Inoue K
Chem Res Toxicol; 1999 Jul; 12(7):623-9. PubMed ID: 10409402
[TBL] [Abstract][Full Text] [Related]
10. Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1.
Shimada T; Hayes CL; Yamazaki H; Amin S; Hecht SS; Guengerich FP; Sutter TR
Cancer Res; 1996 Jul; 56(13):2979-84. PubMed ID: 8674051
[TBL] [Abstract][Full Text] [Related]
11. Roles of different forms of cytochrome P450 in the activation of the promutagen 6-aminochrysene to genotoxic metabolites in human liver microsomes.
Yamazaki H; Mimura M; Oda Y; Inui Y; Shiraga T; Iwasaki K; Guengerich FP; Shimada T
Carcinogenesis; 1993 Jul; 14(7):1271-8. PubMed ID: 8330339
[TBL] [Abstract][Full Text] [Related]
12. Development of a high-throughput genotoxicity assay using Umu test strains expressing human cytochrome P450s and NADPH-P450 reductase and bacterial O-acetyltransferase.
Hori H; Hirata D; Fujii W; Oda Y
Environ Mol Mutagen; 2017 May; 58(4):209-216. PubMed ID: 28436560
[TBL] [Abstract][Full Text] [Related]
13. Mechanism-based inactivation of human liver cytochrome P450 2A6 by 8-methoxypsoralen.
Koenigs LL; Peter RM; Thompson SJ; Rettie AE; Trager WF
Drug Metab Dispos; 1997 Dec; 25(12):1407-15. PubMed ID: 9394031
[TBL] [Abstract][Full Text] [Related]
14. Induction of cytochrome P450 1B1 in lung, liver and kidney of rats exposed to diesel exhaust.
Hatanaka N; Yamazaki H; Kizu R; Hayakawa K; Aoki Y; Iwanari M; Nakajima M; Yokoi T
Carcinogenesis; 2001 Dec; 22(12):2033-8. PubMed ID: 11751436
[TBL] [Abstract][Full Text] [Related]
15. Construction of Salmonella typhimurium YG7108 strains, each coexpressing a form of human cytochrome P450 with NADPH-cytochrome P450 reductase.
Fujita K; Nakayama K; Yamazaki Y; Tsuruma K; Yamada M; Nohmi T; Kamataki T
Environ Mol Mutagen; 2001; 38(4):329-38. PubMed ID: 11774365
[TBL] [Abstract][Full Text] [Related]
16. The stimulatory role of human cytochrome b5 in the bioactivation activities of human CYP1A2, 2A6 and 2E1: a new cell expression system to study cytochrome P450 mediated biotransformation.
Duarte MP; Palma BB; Gilep AA; Laires A; Oliveira JS; Usanov SA; Rueff J; Kranendonk M
Mutagenesis; 2005 Mar; 20(2):93-100. PubMed ID: 15728263
[TBL] [Abstract][Full Text] [Related]
17. Oxidation of indole by cytochrome P450 enzymes.
Gillam EM; Notley LM; Cai H; De Voss JJ; Guengerich FP
Biochemistry; 2000 Nov; 39(45):13817-24. PubMed ID: 11076521
[TBL] [Abstract][Full Text] [Related]
18. Genotoxic activation of 2-phenylbenzotriazole-type compounds by human cytochrome P4501A1 and N-acetyltransferase expressed in Salmonella typhimurium umu strains.
Oda Y; Watanabe T; Terao Y; Nukaya H; Wakabayashi K
Mutat Res; 2008 Jun; 654(1):52-7. PubMed ID: 18562244
[TBL] [Abstract][Full Text] [Related]
19. Biotransformation of (-)-camphor by Salmonella typhimurium OY1002/2A6 expressing human CYP2A6 and NADPH-P450 reductase.
Nakahashi H; Miyazawa M
J Oleo Sci; 2011; 60(10):545-8. PubMed ID: 21937854
[TBL] [Abstract][Full Text] [Related]
20. Activation of procarcinogens by human cytochrome P450 enzymes expressed in Escherichia coli. Simplified bacterial systems for genotoxicity assays.
Shimada T; Gillam EM; Sandhu P; Guo Z; Tukey RH; Guengerich FP
Carcinogenesis; 1994 Nov; 15(11):2523-9. PubMed ID: 7955101
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
