These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

192 related articles for article (PubMed ID: 12164375)

  • 1. Predicting blood-brain barrier permeability of drugs: evaluation of different in vitro assays.
    Lohmann C; Hüwel S; Galla HJ
    J Drug Target; 2002 Jun; 10(4):263-76. PubMed ID: 12164375
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Prediction of drug transport through the blood-brain barrier in vivo: a comparison between two in vitro cell models.
    Lundquist S; Renftel M; Brillault J; Fenart L; Cecchelli R; Dehouck MP
    Pharm Res; 2002 Jul; 19(7):976-81. PubMed ID: 12180550
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evaluation of various PAMPA models to identify the most discriminating method for the prediction of BBB permeability.
    Mensch J; Melis A; Mackie C; Verreck G; Brewster ME; Augustijns P
    Eur J Pharm Biopharm; 2010 Mar; 74(3):495-502. PubMed ID: 20067834
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Relationship between permeability status of the blood-brain barrier and in vitro permeability coefficient of a drug.
    Gaillard PJ; de Boer AG
    Eur J Pharm Sci; 2000 Dec; 12(2):95-102. PubMed ID: 11102736
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Validation of in vitro cell-based human blood-brain barrier model using clinical positron emission tomography radioligands to predict in vivo human brain penetration.
    Mabondzo A; Bottlaender M; Guyot AC; Tsaouin K; Deverre JR; Balimane PV
    Mol Pharm; 2010 Oct; 7(5):1805-15. PubMed ID: 20795735
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Physicochemical selectivity of the BBB microenvironment governing passive diffusion--matching with a porcine brain lipid extract artificial membrane permeability model.
    Tsinman O; Tsinman K; Sun N; Avdeef A
    Pharm Res; 2011 Feb; 28(2):337-63. PubMed ID: 20945153
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Comparison of brain capillary endothelial cell-based and epithelial (MDCK-MDR1, Caco-2, and VB-Caco-2) cell-based surrogate blood-brain barrier penetration models.
    Hellinger E; Veszelka S; Tóth AE; Walter F; Kittel A; Bakk ML; Tihanyi K; Háda V; Nakagawa S; Duy TD; Niwa M; Deli MA; Vastag M
    Eur J Pharm Biopharm; 2012 Oct; 82(2):340-51. PubMed ID: 22906709
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mimicking brain tissue binding in an in vitro model of the blood-brain barrier illustrates differences between in vitro and in vivo methods for assessing the rate of brain penetration.
    Heymans M; Sevin E; Gosselet F; Lundquist S; Culot M
    Eur J Pharm Biopharm; 2018 Jun; 127():453-461. PubMed ID: 29602020
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Evaluation of drug penetration into the brain: a double study by in vivo imaging with positron emission tomography and using an in vitro model of the human blood-brain barrier.
    Josserand V; Pélerin H; de Bruin B; Jego B; Kuhnast B; Hinnen F; Ducongé F; Boisgard R; Beuvon F; Chassoux F; Daumas-Duport C; Ezan E; Dollé F; Mabondzo A; Tavitian B
    J Pharmacol Exp Ther; 2006 Jan; 316(1):79-86. PubMed ID: 16210395
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rat brain endothelial cell lines for the study of blood-brain barrier permeability and transport functions.
    Roux F; Couraud PO
    Cell Mol Neurobiol; 2005 Feb; 25(1):41-58. PubMed ID: 15962508
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Similar molecular descriptors determine the in vitro drug permeability in endothelial and epithelial cells.
    Hakkarainen JJ; Pajander J; Laitinen R; Suhonen M; Forsberg MM
    Int J Pharm; 2012 Oct; 436(1-2):426-43. PubMed ID: 22750947
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Drug permeability across a phospholipid vesicle based barrier: a novel approach for studying passive diffusion.
    Flaten GE; Dhanikula AB; Luthman K; Brandl M
    Eur J Pharm Sci; 2006 Jan; 27(1):80-90. PubMed ID: 16246536
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Porcine brain microvessel endothelial cells as an in vitro model to predict in vivo blood-brain barrier permeability.
    Zhang Y; Li CS; Ye Y; Johnson K; Poe J; Johnson S; Bobrowski W; Garrido R; Madhu C
    Drug Metab Dispos; 2006 Nov; 34(11):1935-43. PubMed ID: 16896068
    [TBL] [Abstract][Full Text] [Related]  

  • 14. High throughput artificial membrane permeability assay for blood-brain barrier.
    Di L; Kerns EH; Fan K; McConnell OJ; Carter GT
    Eur J Med Chem; 2003 Mar; 38(3):223-32. PubMed ID: 12667689
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vitro models of the blood-brain barrier to polar permeants: comparison of transmonolayer flux measurements and cell uptake kinetics using cultured cerebral capillary endothelial cells.
    Johnson MD; Anderson BD
    J Pharm Sci; 1999 Jun; 88(6):620-5. PubMed ID: 10350498
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evaluation of the MDR-MDCK cell line as a permeability screen for the blood-brain barrier.
    Wang Q; Rager JD; Weinstein K; Kardos PS; Dobson GL; Li J; Hidalgo IJ
    Int J Pharm; 2005 Jan; 288(2):349-59. PubMed ID: 15620875
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Validation of cell culture models for the intestine and the blood-brain barrier and comparison of drug permeation.
    Bock U; Flötotto T; Haltner E
    ALTEX; 2004; 21 Suppl 3():57-64. PubMed ID: 15057409
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A new PAMPA model using an in-house brain lipid extract for screening the blood-brain barrier permeability of drug candidates.
    Bicker J; Alves G; Fortuna A; Soares-da-Silva P; Falcão A
    Int J Pharm; 2016 Mar; 501(1-2):102-11. PubMed ID: 26836708
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Caco-2 permeability of weakly basic drugs predicted with the double-sink PAMPA pKa(flux) method.
    Avdeef A; Artursson P; Neuhoff S; Lazorova L; Gråsjö J; Tavelin S
    Eur J Pharm Sci; 2005 Mar; 24(4):333-49. PubMed ID: 15734300
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novel application of capillary electrophoresis with a liposome coated capillary for prediction of blood-brain barrier permeability.
    Godyń J; Gucwa D; Kobrlova T; Novak M; Soukup O; Malawska B; Bajda M
    Talanta; 2020 Sep; 217():121023. PubMed ID: 32498842
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.