183 related articles for article (PubMed ID: 12165567)
1. Differential gene expression in a cell culture model of SOD1-related familial motor neurone disease.
Kirby J; Menzies FM; Cookson MR; Bushby K; Shaw PJ
Hum Mol Genet; 2002 Aug; 11(17):2061-75. PubMed ID: 12165567
[TBL] [Abstract][Full Text] [Related]
2. Cu/Zn superoxide dismutase (SOD1) mutations associated with familial amyotrophic lateral sclerosis (ALS) affect cellular free radical release in the presence of oxidative stress.
Cookson MR; Menzies FM; Manning P; Eggett CJ; Figlewicz DA; McNeil CJ; Shaw PJ
Amyotroph Lateral Scler Other Motor Neuron Disord; 2002 Jun; 3(2):75-85. PubMed ID: 12215229
[TBL] [Abstract][Full Text] [Related]
3. Mitochondrial dysfunction in a cell culture model of familial amyotrophic lateral sclerosis.
Menzies FM; Cookson MR; Taylor RW; Turnbull DM; Chrzanowska-Lightowlers ZM; Dong L; Figlewicz DA; Shaw PJ
Brain; 2002 Jul; 125(Pt 7):1522-33. PubMed ID: 12077002
[TBL] [Abstract][Full Text] [Related]
4. Mutant SOD1 alters the motor neuronal transcriptome: implications for familial ALS.
Kirby J; Halligan E; Baptista MJ; Allen S; Heath PR; Holden H; Barber SC; Loynes CA; Wood-Allum CA; Lunec J; Shaw PJ
Brain; 2005 Jul; 128(Pt 7):1686-706. PubMed ID: 15872021
[TBL] [Abstract][Full Text] [Related]
5. Cultured glial cells are resistant to the effects of motor neurone disease-associated SOD1 mutations.
Williams RE; Cookson MR; Fray AE; Manning PM; Menzies FM; Figlewicz DA; Shaw PJ
Neurosci Lett; 2001 Apr; 302(2-3):146-50. PubMed ID: 11290408
[TBL] [Abstract][Full Text] [Related]
6. Analysis of the cytosolic proteome in a cell culture model of familial amyotrophic lateral sclerosis reveals alterations to the proteasome, antioxidant defenses, and nitric oxide synthetic pathways.
Allen S; Heath PR; Kirby J; Wharton SB; Cookson MR; Menzies FM; Banks RE; Shaw PJ
J Biol Chem; 2003 Feb; 278(8):6371-83. PubMed ID: 12475980
[TBL] [Abstract][Full Text] [Related]
7. Mutant SOD1 linked to familial amyotrophic lateral sclerosis, but not wild-type SOD1, induces ER stress in COS7 cells and transgenic mice.
Tobisawa S; Hozumi Y; Arawaka S; Koyama S; Wada M; Nagai M; Aoki M; Itoyama Y; Goto K; Kato T
Biochem Biophys Res Commun; 2003 Apr; 303(2):496-503. PubMed ID: 12659845
[TBL] [Abstract][Full Text] [Related]
8. Cell death in amyotrophic lateral sclerosis: interplay between neuronal and glial cells.
Ferri A; Nencini M; Casciati A; Cozzolino M; Angelini DF; Longone P; Spalloni A; Rotilio G; Carrì MT
FASEB J; 2004 Aug; 18(11):1261-3. PubMed ID: 15208263
[TBL] [Abstract][Full Text] [Related]
9. Mouse motor neuron disease caused by truncated SOD1 with or without C-terminal modification.
Watanabe Y; Yasui K; Nakano T; Doi K; Fukada Y; Kitayama M; Ishimoto M; Kurihara S; Kawashima M; Fukuda H; Adachi Y; Inoue T; Nakashima K
Brain Res Mol Brain Res; 2005 Apr; 135(1-2):12-20. PubMed ID: 15857664
[TBL] [Abstract][Full Text] [Related]
10. Characterization of the caspase cascade in a cell culture model of SOD1-related familial amyotrophic lateral sclerosis: expression, activation and therapeutic effects of inhibition.
Sathasivam S; Grierson AJ; Shaw PJ
Neuropathol Appl Neurobiol; 2005 Oct; 31(5):467-85. PubMed ID: 16150118
[TBL] [Abstract][Full Text] [Related]
11. Selective loss of neurofilament expression in Cu/Zn superoxide dismutase (SOD1) linked amyotrophic lateral sclerosis.
Menzies FM; Grierson AJ; Cookson MR; Heath PR; Tomkins J; Figlewicz DA; Ince PG; Shaw PJ
J Neurochem; 2002 Sep; 82(5):1118-28. PubMed ID: 12358759
[TBL] [Abstract][Full Text] [Related]
12. Oxidative stress and motor neurone disease.
Cookson MR; Shaw PJ
Brain Pathol; 1999 Jan; 9(1):165-86. PubMed ID: 9989458
[TBL] [Abstract][Full Text] [Related]
13. HoxB2 binds mutant SOD1 and is altered in transgenic model of ALS.
Zhai J; Lin H; Canete-Soler R; Schlaepfer WW
Hum Mol Genet; 2005 Sep; 14(18):2629-40. PubMed ID: 16079151
[TBL] [Abstract][Full Text] [Related]
14. Effect of overexpression of wild-type and mutant Cu/Zn-superoxide dismutases on oxidative stress and cell death induced by hydrogen peroxide, 4-hydroxynonenal or serum deprivation: potentiation of injury by ALS-related mutant superoxide dismutases and protection by Bcl-2.
Lee M; Hyun DH; Halliwell B; Jenner P
J Neurochem; 2001 Jul; 78(2):209-20. PubMed ID: 11461956
[TBL] [Abstract][Full Text] [Related]
15. Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA.
Wang J; Xu G; Slunt HH; Gonzales V; Coonfield M; Fromholt D; Copeland NG; Jenkins NA; Borchelt DR
Neurobiol Dis; 2005 Dec; 20(3):943-52. PubMed ID: 16046140
[TBL] [Abstract][Full Text] [Related]
16. Mutant Cu, Zn superoxide dismutase that causes motoneuron degeneration is present in mitochondria in the CNS.
Higgins CM; Jung C; Ding H; Xu Z
J Neurosci; 2002 Mar; 22(6):RC215. PubMed ID: 11886899
[TBL] [Abstract][Full Text] [Related]
17. Mutant SOD1-induced neuronal toxicity is mediated by increased mitochondrial superoxide levels.
Zimmerman MC; Oberley LW; Flanagan SW
J Neurochem; 2007 Aug; 102(3):609-18. PubMed ID: 17394531
[TBL] [Abstract][Full Text] [Related]
18. Mutant SOD1 causes motor neuron disease independent of copper chaperone-mediated copper loading.
Subramaniam JR; Lyons WE; Liu J; Bartnikas TB; Rothstein J; Price DL; Cleveland DW; Gitlin JD; Wong PC
Nat Neurosci; 2002 Apr; 5(4):301-7. PubMed ID: 11889469
[TBL] [Abstract][Full Text] [Related]
19. Impairment of mitochondrial anti-oxidant defence in SOD1-related motor neuron injury and amelioration by ebselen.
Wood-Allum CA; Barber SC; Kirby J; Heath P; Holden H; Mead R; Higginbottom A; Allen S; Beaujeux T; Alexson SE; Ince PG; Shaw PJ
Brain; 2006 Jul; 129(Pt 7):1693-709. PubMed ID: 16702190
[TBL] [Abstract][Full Text] [Related]
20. Detection method of the adjacent motor neuronal death in an in vitro co-culture model of familial ALS-associated Cu/Zn superoxide dismutase.
Park KS; Kim HJ; Choi WJ; Kim M; Lee KW
Biotechnol Lett; 2004 Aug; 26(15):1201-5. PubMed ID: 15289674
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
