161 related articles for article (PubMed ID: 12171558)
1. Hydroxamic acids as pharmacological agents.
Muri EM; Nieto MJ; Sindelar RD; Williamson JS
Curr Med Chem; 2002 Sep; 9(17):1631-53. PubMed ID: 12171558
[TBL] [Abstract][Full Text] [Related]
2. Molecular diversity of hydroxamic acids: part II. Potential therapeutic applications.
Lou B; Yang K
Mini Rev Med Chem; 2003 Sep; 3(6):609-20. PubMed ID: 12871163
[TBL] [Abstract][Full Text] [Related]
3. Asymmetric synthesis of BB-3497--a potent peptide deformylase inhibitor.
Pratt LM; Beckett RP; Davies SJ; Launchbury SB; Miller A; Spavold ZM; Todd RS; Whittaker M
Bioorg Med Chem Lett; 2001 Oct; 11(19):2585-8. PubMed ID: 11551755
[TBL] [Abstract][Full Text] [Related]
4. Identification of novel potent hydroxamic acid inhibitors of peptidyl deformylase and the importance of the hydroxamic acid functionality on inhibition.
Thorarensen A; Deibel MR; Rohrer DC; Vosters AF; Yem AW; Marshall VD; Lynn JC; Bohanon MJ; Tomich PK; Zurenko GE; Sweeney MT; Jensen RM; Nielsen JW; Seest EP; Dolak LA
Bioorg Med Chem Lett; 2001 Jun; 11(11):1355-8. PubMed ID: 11378353
[TBL] [Abstract][Full Text] [Related]
5. Hydroxamic acid derivatives as potent peptide deformylase inhibitors and antibacterial agents.
Apfel C; Banner DW; Bur D; Dietz M; Hirata T; Hubschwerlen C; Locher H; Page MG; Pirson W; Rossé G; Specklin JL
J Med Chem; 2000 Jun; 43(12):2324-31. PubMed ID: 10882358
[TBL] [Abstract][Full Text] [Related]
6. Alzheimer's amyloid precursor protein alpha-secretase is inhibited by hydroxamic acid-based zinc metalloprotease inhibitors: similarities to the angiotensin converting enzyme secretase.
Parvathy S; Hussain I; Karran EH; Turner AJ; Hooper NM
Biochemistry; 1998 Feb; 37(6):1680-5. PubMed ID: 9484239
[TBL] [Abstract][Full Text] [Related]
7. Structure-activity relationships of the peptide deformylase inhibitor BB-3497: modification of the metal binding group.
Smith HK; Beckett RP; Clements JM; Doel S; East SP; Launchbury SB; Pratt LM; Spavold ZM; Thomas W; Todd RS; Whittaker M
Bioorg Med Chem Lett; 2002 Dec; 12(24):3595-9. PubMed ID: 12443784
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and SAR of bicyclic heteroaryl hydroxamic acid MMP and TACE inhibitors.
Zask A; Gu Y; Albright JD; Du X; Hogan M; Levin JI; Chen JM; Killar LM; Sung A; DiJoseph JF; Sharr MA; Roth CE; Skala S; Jin G; Cowling R; Mohler KM; Barone D; Black R; March C; Skotnicki JS
Bioorg Med Chem Lett; 2003 Apr; 13(8):1487-90. PubMed ID: 12668018
[TBL] [Abstract][Full Text] [Related]
9. Inhibition and structure-activity studies of methionine hydroxamic acid derivatives with bacterial peptide deformylase.
Grant SK; Green BG; Kozarich JW
Bioorg Chem; 2001 Aug; 29(4):211-22. PubMed ID: 16256693
[TBL] [Abstract][Full Text] [Related]
10. Sulfonamide-based hydroxamic acids as potent inhibitors of mouse macrophage metalloelastase.
Jeng AY; Chou M; Parker DT
Bioorg Med Chem Lett; 1998 Apr; 8(8):897-902. PubMed ID: 9871508
[TBL] [Abstract][Full Text] [Related]
11. 2D-QSAR in hydroxamic acid derivatives as peptide deformylase inhibitors and antibacterial agents.
Gupta MK; Mishra P; Prathipati P; Saxena AK
Bioorg Med Chem; 2002 Dec; 10(12):3713-6. PubMed ID: 12413827
[TBL] [Abstract][Full Text] [Related]
12. Amino hydroxamic acids as potent inhibitors of leukotriene A4 hydrolase.
Hogg JH; Ollmann IR; Haeggström JZ; Wetterholm A; Samuelsson B; Wong CH
Bioorg Med Chem; 1995 Oct; 3(10):1405-15. PubMed ID: 8564408
[TBL] [Abstract][Full Text] [Related]
13. Design and synthesis of Leukotriene A4 hydrolase inhibitors to alleviate idiopathic pulmonary fibrosis and acute lung injury.
Li X; Xie M; Lu C; Mao J; Cao Y; Yang Y; Wei Y; Liu X; Cao S; Song Y; Peng J; Zhou Y; Jiang Q; Lin G; Qin S; Qi M; Hou M; Liu X; Zhou H; Yang G; Yang C
Eur J Med Chem; 2020 Oct; 203():112614. PubMed ID: 32679453
[TBL] [Abstract][Full Text] [Related]
14. Actinonin, a naturally occurring antibacterial agent, is a potent deformylase inhibitor.
Chen DZ; Patel DV; Hackbarth CJ; Wang W; Dreyer G; Young DC; Margolis PS; Wu C; Ni ZJ; Trias J; White RJ; Yuan Z
Biochemistry; 2000 Feb; 39(6):1256-62. PubMed ID: 10684604
[TBL] [Abstract][Full Text] [Related]
15. Hydroxamic acids as potent inhibitors of Fe(II) and Mn(II) E. coli methionine aminopeptidase: biological activities and X-ray structures of oxazole hydroxamate-EcMetAP-Mn complexes.
Huguet F; Melet A; Alves de Sousa R; Lieutaud A; Chevalier J; Maigre L; Deschamps P; Tomas A; Leulliot N; Pages JM; Artaud I
ChemMedChem; 2012 Jun; 7(6):1020-30. PubMed ID: 22489069
[TBL] [Abstract][Full Text] [Related]
16. Solid-phase synthesis of di- and tripeptidic hydroxamic acids as inhibitors of procollagen C-proteinase.
Dankwardt SM; Billedeau RJ; Lawley LK; Abbot SC; Martin RL; Chan CS; Van Wart HE; Walker KA
Bioorg Med Chem Lett; 2000 Nov; 10(22):2513-6. PubMed ID: 11086718
[TBL] [Abstract][Full Text] [Related]
17. Indole amide hydroxamic acids as potent inhibitors of histone deacetylases.
Dai Y; Guo Y; Guo J; Pease LJ; Li J; Marcotte PA; Glaser KB; Tapang P; Albert DH; Richardson PL; Davidsen SK; Michaelides MR
Bioorg Med Chem Lett; 2003 Jun; 13(11):1897-901. PubMed ID: 12749893
[TBL] [Abstract][Full Text] [Related]
18. Structural requirements of HDAC inhibitors: SAHA analogs functionalized adjacent to the hydroxamic acid.
Bieliauskas AV; Weerasinghe SV; Pflum MK
Bioorg Med Chem Lett; 2007 Apr; 17(8):2216-9. PubMed ID: 17307359
[TBL] [Abstract][Full Text] [Related]
19. N-alkyl urea hydroxamic acids as a new class of peptide deformylase inhibitors with antibacterial activity.
Hackbarth CJ; Chen DZ; Lewis JG; Clark K; Mangold JB; Cramer JA; Margolis PS; Wang W; Koehn J; Wu C; Lopez S; Withers G; Gu H; Dunn E; Kulathila R; Pan SH; Porter WL; Jacobs J; Trias J; Patel DV; Weidmann B; White RJ; Yuan Z
Antimicrob Agents Chemother; 2002 Sep; 46(9):2752-64. PubMed ID: 12183225
[TBL] [Abstract][Full Text] [Related]
20. Isoxazole-3-hydroxamic acid derivatives as peptide deformylase inhibitors and potential antibacterial agents.
Calí P; Naerum L; Mukhija S; Hjelmencrantz A
Bioorg Med Chem Lett; 2004 Dec; 14(24):5997-6000. PubMed ID: 15546716
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
