BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

384 related articles for article (PubMed ID: 12171941)

  • 1. The N-terminal SH2 domains of Syk and ZAP-70 mediate phosphotyrosine-independent binding to integrin beta cytoplasmic domains.
    Woodside DG; Obergfell A; Talapatra A; Calderwood DA; Shattil SJ; Ginsberg MH
    J Biol Chem; 2002 Oct; 277(42):39401-8. PubMed ID: 12171941
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of Syk protein tyrosine kinase through interaction with integrin beta cytoplasmic domains.
    Woodside DG; Obergfell A; Leng L; Wilsbacher JL; Miranti CK; Brugge JS; Shattil SJ; Ginsberg MH
    Curr Biol; 2001 Nov; 11(22):1799-804. PubMed ID: 11719224
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Solution structure of the C-terminal SH2 domain of the human tyrosine kinase Syk complexed with a phosphotyrosine pentapeptide.
    Narula SS; Yuan RW; Adams SE; Green OM; Green J; Philips TB; Zydowsky LD; Botfield MC; Hatada M; Laird ER
    Structure; 1995 Oct; 3(10):1061-73. PubMed ID: 8590001
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Analysis of the interaction of ZAP-70 and syk protein-tyrosine kinases with the T-cell antigen receptor by plasmon resonance.
    Bu JY; Shaw AS; Chan AC
    Proc Natl Acad Sci U S A; 1995 May; 92(11):5106-10. PubMed ID: 7761456
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ZAP-70 binding specificity to T cell receptor tyrosine-based activation motifs: the tandem SH2 domains of ZAP-70 bind distinct tyrosine-based activation motifs with varying affinity.
    Isakov N; Wange RL; Burgess WH; Watts JD; Aebersold R; Samelson LE
    J Exp Med; 1995 Jan; 181(1):375-80. PubMed ID: 7528772
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Src homology 2 domains of Syk and Lyn bind to tyrosine-phosphorylated subunits of the high affinity IgE receptor.
    Kihara H; Siraganian RP
    J Biol Chem; 1994 Sep; 269(35):22427-32. PubMed ID: 8071371
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Src kinase activation by direct interaction with the integrin beta cytoplasmic domain.
    Arias-Salgado EG; Lizano S; Sarkar S; Brugge JS; Ginsberg MH; Shattil SJ
    Proc Natl Acad Sci U S A; 2003 Nov; 100(23):13298-302. PubMed ID: 14593208
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular basis for a direct interaction between the Syk protein-tyrosine kinase and phosphoinositide 3-kinase.
    Moon KD; Post CB; Durden DL; Zhou Q; De P; Harrison ML; Geahlen RL
    J Biol Chem; 2005 Jan; 280(2):1543-51. PubMed ID: 15536084
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interaction of p72syk with the gamma and beta subunits of the high-affinity receptor for immunoglobulin E, Fc epsilon RI.
    Shiue L; Green J; Green OM; Karas JL; Morgenstern JP; Ram MK; Taylor MK; Zoller MJ; Zydowsky LD; Bolen JB
    Mol Cell Biol; 1995 Jan; 15(1):272-81. PubMed ID: 7528327
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of the pp72syk protein tyrosine kinase by platelet integrin alpha IIb beta 3.
    Gao J; Zoller KE; Ginsberg MH; Brugge JS; Shattil SJ
    EMBO J; 1997 Nov; 16(21):6414-25. PubMed ID: 9351824
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of the roles of SH2 domain-containing proteins in T-lymphocyte activation by using dominant negative SH2 domains.
    Northrop JP; Pustelnik MJ; Lu AT; Grove JR
    Mol Cell Biol; 1996 May; 16(5):2255-63. PubMed ID: 8628292
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Interaction of phosphorylated FcepsilonRIgamma immunoglobulin receptor tyrosine activation motif-based peptides with dual and single SH2 domains of p72syk. Assessment of binding parameters and real time binding kinetics.
    Chen T; Repetto B; Chizzonite R; Pullar C; Burghardt C; Dharm E; Zhao Z; Carroll R; Nunes P; Basu M; Danho W; Visnick M; Kochan J; Waugh D; Gilfillan AM
    J Biol Chem; 1996 Oct; 271(41):25308-15. PubMed ID: 8810294
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of electrostatic interactions in SH2 domain recognition: salt-dependence of tyrosyl-phosphorylated peptide binding to the tandem SH2 domain of the Syk kinase and the single SH2 domain of the Src kinase.
    Grucza RA; Bradshaw JM; Mitaxov V; Waksman G
    Biochemistry; 2000 Aug; 39(33):10072-81. PubMed ID: 10955995
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Modification by covalent reaction or oxidation of cysteine residues in the tandem-SH2 domains of ZAP-70 and Syk can block phosphopeptide binding.
    Visperas PR; Winger JA; Horton TM; Shah NH; Aum DJ; Tao A; Barros T; Yan Q; Wilson CG; Arkin MR; Weiss A; Kuriyan J
    Biochem J; 2015 Jan; 465(1):149-61. PubMed ID: 25287889
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling.
    Calderwood DA; Fujioka Y; de Pereda JM; García-Alvarez B; Nakamoto T; Margolis B; McGlade CJ; Liddington RC; Ginsberg MH
    Proc Natl Acad Sci U S A; 2003 Mar; 100(5):2272-7. PubMed ID: 12606711
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of the site in the Syk protein tyrosine kinase that binds the SH2 domain of Lck.
    Couture C; Deckert M; Williams S; Russo FO; Altman A; Mustelin T
    J Biol Chem; 1996 Sep; 271(39):24294-9. PubMed ID: 8798676
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Syk protein-tyrosine kinase is regulated by tyrosine-phosphorylated Ig alpha/Ig beta immunoreceptor tyrosine activation motif binding and autophosphorylation.
    Rowley RB; Burkhardt AL; Chao HG; Matsueda GR; Bolen JB
    J Biol Chem; 1995 May; 270(19):11590-4. PubMed ID: 7538118
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Syk and ZAP-70 mediate recruitment of p56lck/CD4 to the activated T cell receptor/CD3/zeta complex.
    Thome M; Duplay P; Guttinger M; Acuto O
    J Exp Med; 1995 Jun; 181(6):1997-2006. PubMed ID: 7539035
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural basis for Syk tyrosine kinase ubiquity in signal transduction pathways revealed by the crystal structure of its regulatory SH2 domains bound to a dually phosphorylated ITAM peptide.
    Fütterer K; Wong J; Grucza RA; Chan AC; Waksman G
    J Mol Biol; 1998 Aug; 281(3):523-37. PubMed ID: 9698567
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Protein tyrosine kinases Syk and ZAP-70 display distinct requirements for Src family kinases in immune response receptor signal transduction.
    Zoller KE; MacNeil IA; Brugge JS
    J Immunol; 1997 Feb; 158(4):1650-9. PubMed ID: 9029101
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.