235 related articles for article (PubMed ID: 12173932)
1. Human cystathionine beta-synthase is a heme sensor protein. Evidence that the redox sensor is heme and not the vicinal cysteines in the CXXC motif seen in the crystal structure of the truncated enzyme.
Taoka S; Lepore BW; Kabil O; Ojha S; Ringe D; Banerjee R
Biochemistry; 2002 Aug; 41(33):10454-61. PubMed ID: 12173932
[TBL] [Abstract][Full Text] [Related]
2. Redox regulation and reaction mechanism of human cystathionine-beta-synthase: a PLP-dependent hemesensor protein.
Banerjee R; Zou CG
Arch Biochem Biophys; 2005 Jan; 433(1):144-56. PubMed ID: 15581573
[TBL] [Abstract][Full Text] [Related]
3. Structure of human cystathionine beta-synthase: a unique pyridoxal 5'-phosphate-dependent heme protein.
Meier M; Janosik M; Kery V; Kraus JP; Burkhard P
EMBO J; 2001 Aug; 20(15):3910-6. PubMed ID: 11483494
[TBL] [Abstract][Full Text] [Related]
4. Characterization of the heme and pyridoxal phosphate cofactors of human cystathionine beta-synthase reveals nonequivalent active sites.
Taoka S; West M; Banerjee R
Biochemistry; 1999 Mar; 38(9):2738-44. PubMed ID: 10052944
[TBL] [Abstract][Full Text] [Related]
5. Visualization of PLP-bound intermediates in hemeless variants of human cystathionine beta-synthase: evidence that lysine 119 is a general base.
Evande R; Ojha S; Banerjee R
Arch Biochem Biophys; 2004 Jul; 427(2):188-96. PubMed ID: 15196993
[TBL] [Abstract][Full Text] [Related]
6. Assignment of enzymatic functions to specific regions of the PLP-dependent heme protein cystathionine beta-synthase.
Taoka S; Widjaja L; Banerjee R
Biochemistry; 1999 Oct; 38(40):13155-61. PubMed ID: 10529187
[TBL] [Abstract][Full Text] [Related]
7. Effect of the disease-causing R266K mutation on the heme and PLP environments of human cystathionine β-synthase.
Smith AT; Su Y; Stevens DJ; Majtan T; Kraus JP; Burstyn JN
Biochemistry; 2012 Aug; 51(32):6360-70. PubMed ID: 22738154
[TBL] [Abstract][Full Text] [Related]
8. Alleviation of intrasteric inhibition by the pathogenic activation domain mutation, D444N, in human cystathionine beta-synthase.
Evande R; Blom H; Boers GH; Banerjee R
Biochemistry; 2002 Oct; 41(39):11832-7. PubMed ID: 12269827
[TBL] [Abstract][Full Text] [Related]
9. Deletion of the regulatory domain in the pyridoxal phosphate-dependent heme protein cystathionine beta-synthase alleviates the defect observed in a catalytic site mutant.
Kabil O; Banerjee R
J Biol Chem; 1999 Oct; 274(44):31256-60. PubMed ID: 10531322
[TBL] [Abstract][Full Text] [Related]
10. Reaction mechanism and regulation of cystathionine beta-synthase.
Banerjee R; Evande R; Kabil O; Ojha S; Taoka S
Biochim Biophys Acta; 2003 Apr; 1647(1-2):30-5. PubMed ID: 12686104
[TBL] [Abstract][Full Text] [Related]
11. Modulation of cystathionine beta-synthase activity by the Arg-51 and Arg-224 mutations.
Ozaki S; Inada A; Sada K
Biosci Biotechnol Biochem; 2008 Sep; 72(9):2318-23. PubMed ID: 18776696
[TBL] [Abstract][Full Text] [Related]
12. Allosteric communication between the pyridoxal 5'-phosphate (PLP) and heme sites in the H2S generator human cystathionine β-synthase.
Yadav PK; Xie P; Banerjee R
J Biol Chem; 2012 Nov; 287(45):37611-20. PubMed ID: 22977242
[TBL] [Abstract][Full Text] [Related]
13. Binding of pyridoxal 5'-phosphate to the heme protein human cystathionine beta-synthase.
Kery V; Poneleit L; Meyer JD; Manning MC; Kraus JP
Biochemistry; 1999 Mar; 38(9):2716-24. PubMed ID: 10052942
[TBL] [Abstract][Full Text] [Related]
14. Pyridoxal phosphate binding sites are similar in human heme-dependent and yeast heme-independent cystathionine beta-synthases. Evidence from 31P NMR and pulsed EPR spectroscopy that heme and PLP cofactors are not proximal in the human enzyme.
Kabil O; Toaka S; LoBrutto R; Shoemaker R; Banerjee R
J Biol Chem; 2001 Jun; 276(22):19350-5. PubMed ID: 11278994
[TBL] [Abstract][Full Text] [Related]
15. Allosteric control of human cystathionine β-synthase activity by a redox active disulfide bond.
Niu W; Wang J; Qian J; Wang M; Wu P; Chen F; Yan S
J Biol Chem; 2018 Feb; 293(7):2523-2533. PubMed ID: 29298893
[TBL] [Abstract][Full Text] [Related]
16. Resonance Raman characterization of the heme cofactor in cystathionine beta-synthase. Identification of the Fe-S(Cys) vibration in the six-coordinate low-spin heme.
Green EL; Taoka S; Banerjee R; Loehr TM
Biochemistry; 2001 Jan; 40(2):459-63. PubMed ID: 11148040
[TBL] [Abstract][Full Text] [Related]
17. Mutagenesis studies of human cystathionine beta-synthase: residues important for heme binding and substrate interactions.
Ozaki S; Sakaguchi C; Nakahara A; Yoshiya M
Protein Pept Lett; 2010 Mar; 17(3):351-5. PubMed ID: 19594435
[TBL] [Abstract][Full Text] [Related]
18. Functional properties of the active core of human cystathionine beta-synthase crystals.
Bruno S; Schiaretti F; Burkhard P; Kraus JP; Janosik M; Mozzarelli A
J Biol Chem; 2001 Jan; 276(1):16-9. PubMed ID: 11042162
[TBL] [Abstract][Full Text] [Related]
19. Crystal Structures of Cystathionine β-Synthase from Saccharomyces cerevisiae: One Enzymatic Step at a Time.
Tu Y; Kreinbring CA; Hill M; Liu C; Petsko GA; McCune CD; Berkowitz DB; Liu D; Ringe D
Biochemistry; 2018 Jun; 57(22):3134-3145. PubMed ID: 29630349
[TBL] [Abstract][Full Text] [Related]
20. Structural insights into mutations of cystathionine beta-synthase.
Meier M; Oliveriusova J; Kraus JP; Burkhard P
Biochim Biophys Acta; 2003 Apr; 1647(1-2):206-13. PubMed ID: 12686134
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
