BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

321 related articles for article (PubMed ID: 12176806)

  • 1. Lifelong voluntary joint loading increases osteoarthritis in mice housing a deletion mutation in type II procollagen gene, and slightly also in non-transgenic mice.
    Lapveteläinen T; Hyttinen MM; Säämänen AM; Långsjö T; Sahlman J; Felszeghy S; Vuorio E; Helminen HJ
    Ann Rheum Dis; 2002 Sep; 61(9):810-7. PubMed ID: 12176806
    [TBL] [Abstract][Full Text] [Related]  

  • 2. More knee joint osteoarthritis (OA) in mice after inactivation of one allele of type II procollagen gene but less OA after lifelong voluntary wheel running exercise.
    Lapveteläinen T; Hyttinen M; Lindblom J; Långsjö TK; Sironen R; Li SW; Arita M; Prockop DJ; Puustjärvi K; Helminen HJ
    Osteoarthritis Cartilage; 2001 Feb; 9(2):152-60. PubMed ID: 11237662
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expression of Sox9 and type IIA procollagen during attempted repair of articular cartilage damage in a transgenic mouse model of osteoarthritis.
    Salminen H; Vuorio E; Säämänen AM
    Arthritis Rheum; 2001 Apr; 44(4):947-55. PubMed ID: 11315934
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Analysis of arthritic lesions in the Del1 mouse: a model for osteoarthritis.
    Säämänen AM; Hyttinen M; Vuorio E
    Methods Mol Med; 2007; 136():283-302. PubMed ID: 17983156
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Up-regulation of cartilage oligomeric matrix protein at the onset of articular cartilage degeneration in a transgenic mouse model of osteoarthritis.
    Salminen H; Perälä M; Lorenzo P; Saxne T; Heinegård D; Säämänen AM; Vuorio E
    Arthritis Rheum; 2000 Aug; 43(8):1742-8. PubMed ID: 10943864
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Osteoarthritis-like lesions in transgenic mice harboring a small deletion mutation in type II collagen gene.
    Säämänen AK; Salminen HJ; Dean PB; De Crombrugghe B; Vuorio EI; Metsäranta MP
    Osteoarthritis Cartilage; 2000 Jul; 8(4):248-57. PubMed ID: 10903878
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Abnormal response to physical activity in femurs after heterozygous inactivation of one allele of the Col2a1 gene for type II collagen in mice.
    Nieminen J; Sahlman J; Hirvonen T; Jämsä T; Tuukkanen J; Kovanen V; Kröger H; Jurvelin J; Arita M; Li SW; Prockop DJ; Hyttinen MM; Helminen HJ; Lapveteläinen T; Puustjärvi K
    Calcif Tissue Int; 2005 Aug; 77(2):104-12. PubMed ID: 15920676
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Minor influence of lifelong voluntary exercise on composition, structure, and incidence of osteoarthritis in tibial articular cartilage of mice compared with major effects caused by growth, maturation, and aging.
    Närhi T; Siitonen U; Lehto LJ; Hyttinen MM; Arokoski JP; Brama PA; Jurvelin JS; Helminen HJ; Julkunen P
    Connect Tissue Res; 2011 Oct; 52(5):380-92. PubMed ID: 21405978
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lifelong moderate running training increases the incidence and severity of osteoarthritis in the knee joint of C57BL mice.
    Lapveteläinen T; Nevalainen T; Parkkinen JJ; Arokoski J; Kiraly K; Hyttinen M; Halonen P; Helminen HJ
    Anat Rec; 1995 Jun; 242(2):159-65. PubMed ID: 7668400
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Articular cartilage superficial zone collagen birefringence reduced and cartilage thickness increased before surface fibrillation in experimental osteoarthritis.
    Panula HE; Hyttinen MM; Arokoski JP; Långsjö TK; Pelttari A; Kiviranta I; Helminen HJ
    Ann Rheum Dis; 1998 Apr; 57(4):237-45. PubMed ID: 9709181
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Up regulation of cathepsin K expression in articular chondrocytes in a transgenic mouse model for osteoarthritis.
    Morko JP; Söderström M; Säämänen AM; Salminen HJ; Vuorio EI
    Ann Rheum Dis; 2004 Jun; 63(6):649-55. PubMed ID: 15140771
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Early post-traumatic osteoarthritis-like changes in human articular cartilage following rupture of the anterior cruciate ligament.
    Nelson F; Billinghurst RC; Pidoux I; Reiner A; Langworthy M; McDermott M; Malogne T; Sitler DF; Kilambi NR; Lenczner E; Poole AR
    Osteoarthritis Cartilage; 2006 Feb; 14(2):114-9. PubMed ID: 16242972
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Age matters: collagen birefringence of superficial articular cartilage is increased in young guinea-pigs but decreased in older animals after identical physiological type of joint loading.
    Hyttinen MM; Arokoski JP; Parkkinen JJ; Lammi MJ; Lapveteläinen T; Mauranen K; Király K; Tammi MI; Helminen HJ
    Osteoarthritis Cartilage; 2001 Nov; 9(8):694-701. PubMed ID: 11795988
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The beneficial effects of exercise on cartilage are lost in mice with reduced levels of ECSOD in tissues.
    Pate KM; Sherk VD; Carpenter RD; Weaver M; Crapo S; Gally F; Chatham LS; Goldstrohm DA; Crapo JD; Kohrt WM; Bowler RP; Oberley-Deegan RE; Regan EA
    J Appl Physiol (1985); 2015 Mar; 118(6):760-7. PubMed ID: 25593283
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regional differences of tibial and femoral cartilage in the chondrocyte gene expression, immunhistochemistry and composite in different stages of osteoarthritis.
    Lahm A; Dabravolski D; Spank H; Merk H; Esser J; Kasch R
    Tissue Cell; 2017 Apr; 49(2 Pt B):249-256. PubMed ID: 28302318
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Correlation network analysis shows divergent effects of a long-term, high-fat diet and exercise on early stage osteoarthritis phenotypes in mice.
    Griffin TM; Batushansky A; Hudson J; Lopes EBP
    J Sport Health Sci; 2020 Mar; 9(2):119-131. PubMed ID: 32099720
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inactivation of one allele of the type II collagen gene alters the collagen network in murine articular cartilage and makes cartilage softer.
    Hyttinen MM; Töyräs J; Lapveteläinen T; Lindblom J; Prockop DJ; Li SW; Arita M; Jurvelin JS; Helminen HJ
    Ann Rheum Dis; 2001 Mar; 60(3):262-8. PubMed ID: 11171689
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential expression patterns of matrix metalloproteinases and their inhibitors during development of osteoarthritis in a transgenic mouse model.
    Salminen HJ; Säämänen AM; Vankemmelbeke MN; Auho PK; Perälä MP; Vuorio EI
    Ann Rheum Dis; 2002 Jul; 61(7):591-7. PubMed ID: 12079898
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Type II collagen synthesis in the articular cartilage of a rabbit model of osteoarthritis: expression of type II collagen C-propeptide and mRNA especially during early-stage osteoarthritis.
    Hotta H; Yamada H; Takaishi H; Abe T; Morioka H; Kikuchi T; Fujikawa K; Toyama Y
    J Orthop Sci; 2005 Nov; 10(6):595-607. PubMed ID: 16307185
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hsp90 inhibition protects against biomechanically induced osteoarthritis in rats.
    Siebelt M; Jahr H; Groen HC; Sandker M; Waarsing JH; Kops N; Müller C; van Eden W; de Jong M; Weinans H
    Arthritis Rheum; 2013 Aug; 65(8):2102-12. PubMed ID: 23666904
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.