BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

921 related articles for article (PubMed ID: 12181440)

  • 1. Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification.
    Maglich JM; Stoltz CM; Goodwin B; Hawkins-Brown D; Moore JT; Kliewer SA
    Mol Pharmacol; 2002 Sep; 62(3):638-46. PubMed ID: 12181440
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response.
    Wei P; Zhang J; Dowhan DH; Han Y; Moore DD
    Pharmacogenomics J; 2002; 2(2):117-26. PubMed ID: 12049174
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PXR, CAR and drug metabolism.
    Willson TM; Kliewer SA
    Nat Rev Drug Discov; 2002 Apr; 1(4):259-66. PubMed ID: 12120277
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR.
    Xie W; Barwick JL; Simon CM; Pierce AM; Safe S; Blumberg B; Guzelian PS; Evans RM
    Genes Dev; 2000 Dec; 14(23):3014-23. PubMed ID: 11114890
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of drug transporter gene expression by nuclear receptors.
    Staudinger JL; Madan A; Carol KM; Parkinson A
    Drug Metab Dispos; 2003 May; 31(5):523-7. PubMed ID: 12695338
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The role of hepatocyte RXR alpha in xenobiotic-sensing nuclear receptor-mediated pathways.
    Cai Y; Konishi T; Han G; Campwala KH; French SW; Wan YJ
    Eur J Pharm Sci; 2002 Feb; 15(1):89-96. PubMed ID: 11803135
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Genomewide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR and PPARα in primary human hepatocytes.
    Kandel BA; Thomas M; Winter S; Damm G; Seehofer D; Burk O; Schwab M; Zanger UM
    Biochim Biophys Acta; 2016 Sep; 1859(9):1218-1227. PubMed ID: 26994748
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Xenobiotic-induced hepatocyte proliferation associated with constitutive active/androstane receptor (CAR) or peroxisome proliferator-activated receptor α (PPARα) is enhanced by pregnane X receptor (PXR) activation in mice.
    Shizu R; Benoki S; Numakura Y; Kodama S; Miyata M; Yamazoe Y; Yoshinari K
    PLoS One; 2013; 8(4):e61802. PubMed ID: 23626729
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity.
    Zhang J; Huang W; Qatanani M; Evans RM; Moore DD
    J Biol Chem; 2004 Nov; 279(47):49517-22. PubMed ID: 15358766
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Coordinated roles of pregnane X receptor and constitutive androstane receptor in autoinduction of voriconazole metabolism in mice.
    Ohbuchi M; Yoshinari K; Kaneko H; Matsumoto S; Inoue A; Kawamura A; Usui T; Yamazoe Y
    Antimicrob Agents Chemother; 2013 Mar; 57(3):1332-8. PubMed ID: 23274663
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The xenobiotic-sensing nuclear receptors pregnane X receptor, constitutive androstane receptor, and orphan nuclear receptor hepatocyte nuclear factor 4alpha in the regulation of human steroid-/bile acid-sulfotransferase.
    Echchgadda I; Song CS; Oh T; Ahmed M; De La Cruz IJ; Chatterjee B
    Mol Endocrinol; 2007 Sep; 21(9):2099-111. PubMed ID: 17595319
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The ratio of constitutive androstane receptor to pregnane X receptor determines the activity of guggulsterone against the Cyp2b10 promoter.
    Ding X; Staudinger JL
    J Pharmacol Exp Ther; 2005 Jul; 314(1):120-7. PubMed ID: 15833898
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression.
    Wang H; Faucette S; Sueyoshi T; Moore R; Ferguson S; Negishi M; LeCluyse EL
    J Biol Chem; 2003 Apr; 278(16):14146-52. PubMed ID: 12571232
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR.
    Tolson AH; Wang H
    Adv Drug Deliv Rev; 2010 Oct; 62(13):1238-49. PubMed ID: 20727377
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands.
    Moore LB; Parks DJ; Jones SA; Bledsoe RK; Consler TG; Stimmel JB; Goodwin B; Liddle C; Blanchard SG; Willson TM; Collins JL; Kliewer SA
    J Biol Chem; 2000 May; 275(20):15122-7. PubMed ID: 10748001
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor.
    Staudinger J; Liu Y; Madan A; Habeebu S; Klaassen CD
    Drug Metab Dispos; 2001 Nov; 29(11):1467-72. PubMed ID: 11602523
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human CYP2C8 is transcriptionally regulated by the nuclear receptors constitutive androstane receptor, pregnane X receptor, glucocorticoid receptor, and hepatic nuclear factor 4alpha.
    Ferguson SS; Chen Y; LeCluyse EL; Negishi M; Goldstein JA
    Mol Pharmacol; 2005 Sep; 68(3):747-57. PubMed ID: 15933212
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of xenobiotic and bile acid metabolism by the nuclear pregnane X receptor.
    Kliewer SA; Willson TM
    J Lipid Res; 2002 Mar; 43(3):359-64. PubMed ID: 11893771
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transcriptional activation of PPARalpha by phenobarbital in the absence of CAR and PXR.
    Tamasi V; Juvan P; Beer M; Rozman D; Meyer UA
    Mol Pharm; 2009; 6(5):1573-81. PubMed ID: 19708687
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity.
    Guo GL; Lambert G; Negishi M; Ward JM; Brewer HB; Kliewer SA; Gonzalez FJ; Sinal CJ
    J Biol Chem; 2003 Nov; 278(46):45062-71. PubMed ID: 12923173
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 47.